product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-SAPK/JNK (Thr183/Tyr185) (81E11) Rabbit mAb (Sepharose Bead Conjugate)
catalog :
4306
clonality :
monoclonal
host :
rabbit
conjugate :
Bead
antigen modification :
phosphorylated
clone name :
81E11
reactivity :
human, mouse, rat
application :
immunoprecipitation
citations: 19
Published Application/Species/Sample/DilutionReference
  • immunoprecipitation; human; 1:20; loading ...; fig 7e
Salvucci O, Ohnuki H, Maric D, Hou X, Li X, Yoon S, et al. EphrinB2 controls vessel pruning through STAT1-JNK3 signalling. Nat Commun. 2015;6:6576 pubmed publisher
Li C, Lun W, Zhao X, Lei S, Guo Y, Ma J, et al. Allicin alleviates inflammation of trinitrobenzenesulfonic acid-induced rats and suppresses P38 and JNK pathways in Caco-2 cells. Mediators Inflamm. 2015;2015:434692 pubmed publisher
Yu G, Lee Y, Cheng C, Wu C, Song J, Gallick G, et al. RSK promotes prostate cancer progression in bone through ING3, CKAP2, and PTK6-mediated cell survival. Mol Cancer Res. 2015;13:348-57 pubmed publisher
Liu J, Lin X, Yang X, Zhou L, He S, Zhuang S, et al. A novel AP-1/miR-101 regulatory feedback loop and its implication in the migration and invasion of hepatoma cells. Nucleic Acids Res. 2014;42:12041-51 pubmed publisher
Kimura T, Kobayashi S, Hanihara Tatsuzawa F, Sayama A, Maruyama T, Muta T. Responses of macrophages to the danger signals released from necrotic cells. Int Immunol. 2014;26:697-704 pubmed publisher
Zhou H, Guo W, Zhao Y, Wang Y, Zha R, Ding J, et al. MicroRNA-135a acts as a putative tumor suppressor by directly targeting very low density lipoprotein receptor in human gallbladder cancer. Cancer Sci. 2014;105:956-65 pubmed publisher
Kutsukake M, Matsutani T, Tamura K, Matsuda A, Kobayashi M, Tachikawa E, et al. Pioglitazone attenuates lung injury by modulating adipose inflammation. J Surg Res. 2014;189:295-303 pubmed publisher
Ting C, Huang H, Huang T, Wu C, Chen J. The mechanisms by which pardaxin, a natural cationic antimicrobial peptide, targets the endoplasmic reticulum and induces c-FOS. Biomaterials. 2014;35:3627-40 pubmed publisher
Leventaki V, Drakos E, Karanikou M, Psatha K, Lin P, Schlette E, et al. c-JUN N-terminal kinase (JNK) is activated and contributes to tumor cell proliferation in classical Hodgkin lymphoma. Hum Pathol. 2014;45:565-72 pubmed publisher
El Gazzar A, Cai X, Reeves R, Dai Z, Caballero Benítez A, McDonald D, et al. Effects on tumor development and metastatic dissemination by the NKG2D lymphocyte receptor expressed on cancer cells. Oncogene. 2014;33:4932-40 pubmed publisher
Nomura J, Busso N, Ives A, Tsujimoto S, Tamura M, So A, et al. Febuxostat, an inhibitor of xanthine oxidase, suppresses lipopolysaccharide-induced MCP-1 production via MAPK phosphatase-1-mediated inactivation of JNK. PLoS ONE. 2013;8:e75527 pubmed publisher
Cao Y, Xia D, Qi S, Du J, Ma P, Wang S, et al. Epiregulin can promote proliferation of stem cells from the dental apical papilla via MEK/Erk and JNK signalling pathways. Cell Prolif. 2013;46:447-56 pubmed publisher
Chen D, Wang W, Qin J, Wang M, Murugesan S, Nadkarni D, et al. Identification of the ZAK-MKK4-JNK-TGF? signaling pathway as a molecular target for novel synthetic iminoquinone anticancer compound BA-TPQ. Curr Cancer Drug Targets. 2013;13:651-60 pubmed
Yoshikawa N, Shimizu N, Maruyama T, Sano M, Matsuhashi T, Fukuda K, et al. Cardiomyocyte-specific overexpression of HEXIM1 prevents right ventricular hypertrophy in hypoxia-induced pulmonary hypertension in mice. PLoS ONE. 2012;7:e52522 pubmed publisher
Moreno Garcia M, Sommer K, Rincón Arano H, Brault M, Ninomiya Tsuji J, Matesic L, et al. Kinase-independent feedback of the TAK1/TAB1 complex on BCL10 turnover and NF-?B activation. Mol Cell Biol. 2013;33:1149-63 pubmed publisher
Mufson E, He B, Nadeem M, Perez S, Counts S, Leurgans S, et al. Hippocampal proNGF signaling pathways and ?-amyloid levels in mild cognitive impairment and Alzheimer disease. J Neuropathol Exp Neurol. 2012;71:1018-29 pubmed publisher
Lu N, Liu J, Liu J, Zhang C, Jiang F, Wu H, et al. Antagonist effect of triptolide on AKT activation by truncated retinoid X receptor-alpha. PLoS ONE. 2012;7:e35722 pubmed publisher
Wang L, Kou M, Weng C, Hu L, Wang Y, Wu M. Arsenic modulates heme oxygenase-1, interleukin-6, and vascular endothelial growth factor expression in endothelial cells: roles of ROS, NF-?B, and MAPK pathways. Arch Toxicol. 2012;86:879-96 pubmed publisher
Su J, Yen J, Li S, Weng C, Lin M, Ho C, et al. 3',4'-didemethylnobiletin induces phase II detoxification gene expression and modulates PI3K/Akt signaling in PC12 cells. Free Radic Biol Med. 2012;52:126-41 pubmed publisher
product information
SKU :
4306S
Product-Name :
Phospho-SAPK/JNK (Thr183/Tyr185) (81E11) Rabbit mAb (Sepharose Bead Conjugate)
Size :
400 ul
Price-(USD) :
291 USD
Species-x-Reactivity :
H, M, R, Dm, Sc
Applications :
Immunoprecipitation
Product-Category :
MAP Kinase Signaling
Shipping-Temp :
COLD
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
46, 54
Host :
Rabbit
Target :
SAPK/JNK1 (Thr183/Tyr185) phosphate
Primary-Protein :
JNK1
Alt-Names :
JNK,JNK-46,JNK1,JNK1 alpha protein kinase,JNK1 beta protein kinase,JNK1A2,JNK21B1/2,JUN N-terminal kinase,MAP kinase 8,MAPK 8,MAPK8,MK08,Mitogen-activated protein kinase 8,PRKM8,SAPK1,Stress-activated protein kinase 1,Stress-activated protein kinase JNK1,c-Jun N-terminal kinase 1,mitogen-activated protein kinase 8 isoform JNK1 alpha1,mitogen-activated protein kinase 8 isoform JNK1 beta2,protein kinase JNK1
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.