product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
HER2/ErbB2 (D8F12) XP® Rabbit mAb
catalog :
4290P
quantity :
40 ul
price :
135 USD
clonality :
monoclonal
host :
rabbit
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section
more info or order :
Cell Signaling Technology product webpage
citations: 6
Published Application/Species/DilutionReference
  • immunohistochemistry - paraffin section; mouse; fig 6
Mancini M, Lien E, Toker A. Oncogenic AKT1(E17K) mutation induces mammary hyperplasia but prevents HER2-driven tumorigenesis. Oncotarget. 2016;7:17301-13 pubmed publisher
  • western blot; human
Kugel C, Hartsough E, Davies M, Setiady Y, Aplin A. Function-blocking ERBB3 antibody inhibits the adaptive response to RAF inhibitor. Cancer Res. 2014;74:4122-32 pubmed publisher
Liu X, Kano M, Araki T, Cooper O, Fukuoka H, Tone Y, et al. ErbB receptor-driven prolactinomas respond to targeted lapatinib treatment in female transgenic mice. Endocrinology. 2015;156:71-9 pubmed publisher
Zhang X, Deng H, Wang Z. Estrogen activation of the mitogen-activated protein kinase is mediated by ER-α36 in ER-positive breast cancer cells. J Steroid Biochem Mol Biol. 2014;143:434-43 pubmed publisher
Huang W, Ye M, Zhang L, Wu Q, Zhang M, Xu J, et al. FW-04-806 inhibits proliferation and induces apoptosis in human breast cancer cells by binding to N-terminus of Hsp90 and disrupting Hsp90-Cdc37 complex formation. Mol Cancer. 2014;13:150 pubmed publisher
Yin L, Zhang X, Bian X, Guo Y, Wang Z. Disruption of the ER-α36-EGFR/HER2 positive regulatory loops restores tamoxifen sensitivity in tamoxifen resistance breast cancer cells. PLoS ONE. 2014;9:e107369 pubmed publisher
product information
SKU :
4290P
Product-Name :
HER2/ErbB2 (D8F12) XP® Rabbit mAb
Size :
40 ul
Price-(USD) :
135 USD
Species-x-Reactivity :
H, (M, R)
Applications :
Immunohistochemistry (Paraffin)
Product-Category :
RTK
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
185
Host :
Rabbit
Target :
HER2/ErbB2
Primary-Protein :
HER2
Alt-Names :
CD340,ERBB2,HER-2,HER-2/neu,HER2,MLN 19,MLN19,Metastatic lymph node gene 19 protein,NEU,NGL,Proto-oncogene Neu,Proto-oncogene c-ErbB-2,Receptor tyrosine-protein kinase erbB-2,TKR1,Tyrosine kinase-type cell surface receptor HER2,c-erb B2/neu protein,erbB-2,herstatin,neuroblastoma/glioblastoma derived oncogene homolog,p185erbB2,v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (neuro/glioblastoma derived oncogene homolog),v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.