product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Cytochrome c (136F3) Rabbit mAb
catalog :
4280
clonality :
monoclonal
host :
rabbit
conjugate :
nonconjugated
clone name :
136F3
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section
citations: 26
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:1000; loading ...; fig 4c
Lee C, Hanna A, Wang H, Dagnino Acosta A, Joshi A, Knoblauch M, et al. A chemical chaperone improves muscle function in mice with a RyR1 mutation. Nat Commun. 2017;8:14659 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 4e
Patil M, Sharma B, Elattar S, Chang J, Kapil S, Yuan J, et al. Id1 Promotes Obesity by Suppressing Brown Adipose Thermogenesis and White Adipose Browning. Diabetes. 2017;66:1611-1625 pubmed publisher
  • western blot; human; loading ...; fig 5a
Møller A, Kampmann U, Hedegaard J, Thorsen K, Nordentoft I, Vendelbo M, et al. Altered gene expression and repressed markers of autophagy in skeletal muscle of insulin resistant patients with type 2 diabetes. Sci Rep. 2017;7:43775 pubmed publisher
  • western blot; rat; loading ...; fig 3b
Kim T, Terentyeva R, Roder K, Li W, Liu M, Greener I, et al. SK channel enhancers attenuate Ca2+-dependent arrhythmia in hypertrophic hearts by regulating mito-ROS-dependent oxidation and activity of RyR. Cardiovasc Res. 2017;113:343-353 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 2e
Zou T, Chen D, Yang Q, Wang B, Zhu M, Nathanielsz P, et al. Resveratrol supplementation of high-fat diet-fed pregnant mice promotes brown and beige adipocyte development and prevents obesity in male offspring. J Physiol. 2017;595:1547-1562 pubmed publisher
  • western blot; human; 1:500; loading ...; fig 6c
Cao R, Meng Z, Liu T, Wang G, Qian G, Cao T, et al. Decreased TRPM7 inhibits activities and induces apoptosis of bladder cancer cells via ERK1/2 pathway. Oncotarget. 2016;7:72941-72960 pubmed publisher
  • western blot; human; 1:1000; fig 2
Geng J, Li J, Huang T, Zhao K, Chen Q, Guo W, et al. A novel manganese complex selectively induces malignant glioma cell death by targeting mitochondria. Mol Med Rep. 2016;14:1970-8 pubmed publisher
  • western blot; human; loading ...; fig 4d
Qi J, Li T, Bian H, Li F, Ju Y, Gao S, et al. SNAI1 promotes the development of HCC through the enhancement of proliferation and inhibition of apoptosis. FEBS Open Bio. 2016;6:326-37 pubmed publisher
  • western blot; mouse; 1:1000; fig 4
Zhao Y, Xu L, Qiao Z, Gao L, Ding S, Ying X, et al. YiXin-Shu, a ShengMai-San-based traditional Chinese medicine formula, attenuates myocardial ischemia/reperfusion injury by suppressing mitochondrial mediated apoptosis and upregulating liver-X-receptor α. Sci Rep. 2016;6:23025 pubmed publisher
  • western blot; mouse; 1:100; tbl 1
Bertoldo M, Guibert E, Faure M, Guillou F, Ramé C, Nadal Desbarats L, et al. Specific deletion of AMP-activated protein kinase (α1AMPK) in mouse Sertoli cells modifies germ cell quality. Mol Cell Endocrinol. 2016;423:96-112 pubmed publisher
  • western blot; mouse; 1:1000; fig s2
Geng J, Sun X, Wang P, Zhang S, Wang X, Wu H, et al. Kinases Mst1 and Mst2 positively regulate phagocytic induction of reactive oxygen species and bactericidal activity. Nat Immunol. 2015;16:1142-52 pubmed publisher
  • western blot; human; loading ...; fig 4D
Ma H, Yue X, Gao L, Liang X, Yan W, Zhang Z, et al. ZHX2 enhances the cytotoxicity of chemotherapeutic drugs in liver tumor cells by repressing MDR1 via interfering with NF-YA. Oncotarget. 2015;6:1049-63 pubmed
  • western blot; mouse
Sun R, Wang X, Liu Y, Xia M. Dietary supplementation with fish oil alters the expression levels of proteins governing mitochondrial dynamics and prevents high-fat diet-induced endothelial dysfunction. Br J Nutr. 2014;112:145-53 pubmed publisher
  • western blot; human; fig s5
Wang W, Wang Y, Chen H, Xing Y, Li F, Zhang Q, et al. Orphan nuclear receptor TR3 acts in autophagic cell death via mitochondrial signaling pathway. Nat Chem Biol. 2014;10:133-40 pubmed publisher
Du Y, Shang B, Sheng W, Zhang S, Li Y, Miao Q, et al. A recombinantly tailored β-defensin that displays intensive macropinocytosis-mediated uptake exerting potent efficacy against K-Ras mutant pancreatic cancer. Oncotarget. 2016;7:58418-58434 pubmed publisher
Wang S, Liang X, Yang Q, Fu X, Rogers C, Zhu M, et al. Resveratrol induces brown-like adipocyte formation in white fat through activation of AMP-activated protein kinase (AMPK) α1. Int J Obes (Lond). 2015;39:967-76 pubmed publisher
Haddock C, Blomenkamp K, Gautam M, James J, Mielcarska J, Gogol E, et al. PiZ mouse liver accumulates polyubiquitin conjugates that associate with catalytically active 26S proteasomes. PLoS ONE. 2014;9:e106371 pubmed publisher
Gu D, Wang S, Kuiatse I, Wang H, He J, Dai Y, et al. Inhibition of the MDM2 E3 Ligase induces apoptosis and autophagy in wild-type and mutant p53 models of multiple myeloma, and acts synergistically with ABT-737. PLoS ONE. 2014;9:e103015 pubmed publisher
Evans J, Ko Y, Mata W, Saquib M, Eldridge J, Cohen Gadol A, et al. Arachidonic acid induces brain endothelial cell apoptosis via p38-MAPK and intracellular calcium signaling. Microvasc Res. 2015;98:145-58 pubmed publisher
Yang D, Meng X, Xue B, Liu N, Wang X, Zhu H. MiR-942 mediates hepatitis C virus-induced apoptosis via regulation of ISG12a. PLoS ONE. 2014;9:e94501 pubmed publisher
Ezemaduka A, Yu J, Shi X, Zhang K, Yin C, Fu X, et al. A small heat shock protein enables Escherichia coli to grow at a lethal temperature of 50°C conceivably by maintaining cell envelope integrity. J Bacteriol. 2014;196:2004-11 pubmed publisher
Zhang C, Zhou S, Li X, Wang B, Lin N, Feng L, et al. Enhanced antitumor activity by the combination of dasatinib and combretastatin A-4 in vitro and in vivo. Oncol Rep. 2013;29:2275-82 pubmed publisher
Tripathi S, Batra J, Cao W, Sharma K, Patel J, Ranjan P, et al. Influenza A virus nucleoprotein induces apoptosis in human airway epithelial cells: implications of a novel interaction between nucleoprotein and host protein Clusterin. Cell Death Dis. 2013;4:e562 pubmed publisher
Liu N, Du X, Lu J, He B. Diva reduces cell death in response to oxidative stress and cytotoxicity. PLoS ONE. 2012;7:e43180 pubmed publisher
Berens H, Tyler K. The proapoptotic Bcl-2 protein Bax plays an important role in the pathogenesis of reovirus encephalitis. J Virol. 2011;85:3858-71 pubmed publisher
Widenmaier S, Ao Z, Kim S, Warnock G, McIntosh C. Suppression of p38 MAPK and JNK via Akt-mediated inhibition of apoptosis signal-regulating kinase 1 constitutes a core component of the beta-cell pro-survival effects of glucose-dependent insulinotropic polypeptide. J Biol Chem. 2009;284:30372-82 pubmed publisher
product information
SKU :
4280S
Product-Name :
Cytochrome c (136F3) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Immunohistochemistry (Paraffin)
Product-Category :
Apoptosis
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
14
Host :
Rabbit
Target :
cytochrome C
Primary-Protein :
CYCS
Alt-Names :
CYC,CYCS,Cytochrome c,HCS,THC4,cytochrome c, somatic
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.