PI3 Kinase p110α Antibody | Cell Signaling Technology 4255 product information

product summary

company name :

Cell Signaling Technology

product type :

antibody

product name :

PI3 Kinase p110α Antibody

catalog :

4255

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, bovine

application :

western blot, immunoprecipitation, reverse phase protein lysate microarray, other

more info or order :

Cell Signaling Technology product webpage

citations: 12

Published Application/Species/Sample/Dilution	Reference
western blot; human; fig 1c	Wang J, Zhang Y, Xiao Y, Yuan X, Li P, Wang X, et al. Boosting immune surveillance by low-dose PI3K inhibitor facilitates early intervention of breast cancer. Am J Cancer Res. 2021;11:2005-2024 pubmed
western blot; human; 1:2000; loading ...	Wang Z, Goto Y, Allevato M, Wu V, Saddawi Konefka R, Gilardi M, et al. Disruption of the HER3-PI3K-mTOR oncogenic signaling axis and PD-1 blockade as a multimodal precision immunotherapy in head and neck cancer. Nat Commun. 2021;12:2383 pubmed publisher
western blot; human; loading ...; fig 5f	Chen Q, Yang C, Chen L, Zhang J, Ge W, Yuan H, et al. YY1 targets tubulin polymerisation-promoting protein to inhibit migration, invasion and angiogenesis in pancreatic cancer via p38/MAPK and PI3K/AKT pathways. Br J Cancer. 2019;121:912-921 pubmed publisher
western blot; mouse; 1:1000; loading ...; fig 1a	Araiz C, Yan A, Bettedi L, Samuelson I, Virtue S, McGavigan A, et al. Enhanced β-adrenergic signalling underlies an age-dependent beneficial metabolic effect of PI3K p110α inactivation in adipose tissue. Nat Commun. 2019;10:1546 pubmed publisher
other; human; loading ...; fig 4c	Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed publisher
reverse phase protein lysate microarray; human; loading ...; fig st6	Cherniack A, Shen H, Walter V, Stewart C, Murray B, Bowlby R, et al. Integrated Molecular Characterization of Uterine Carcinosarcoma. Cancer Cell. 2017;31:411-423 pubmed publisher
western blot; human; fig 5b	Bhagirath D, Zhao X, Mirza S, West W, Band H, Band V. Mutant PIK3CA Induces EMT in a Cell Type Specific Manner. PLoS ONE. 2016;11:e0167064 pubmed publisher
western blot; mouse; fig 5	Winnay J, Solheim M, Dirice E, Sakaguchi M, Noh H, Kang H, et al. PI3-kinase mutation linked to insulin and growth factor resistance in vivo. J Clin Invest. 2016;126:1401-12 pubmed publisher
western blot; mouse; fig 6	Du L, Chen X, Cao Y, Lu L, Zhang F, Bornstein S, et al. Overexpression of PIK3CA in murine head and neck epithelium drives tumor invasion and metastasis through PDK1 and enhanced TGFÎ² signaling. Oncogene. 2016;35:4641-52 pubmed publisher
western blot; human; fig 1	Kulbe H, Iorio F, Chakravarty P, Milagre C, Moore R, Thompson R, et al. Integrated transcriptomic and proteomic analysis identifies protein kinase CK2 as a key signaling node in an inflammatory cytokine network in ovarian cancer cells. Oncotarget. 2016;7:15648-61 pubmed publisher
	Nelson V, Negrón A, Reid I, Thomas J, Yang L, Lin R, et al. Loss of PI3K p110? in the Adipose Tissue Results in Infertility and Delayed Puberty Onset in Male Mice. Biomed Res Int. 2017;2017:3756089 pubmed publisher
	Cui S, Shi W, Song Z, Wang S, Yu X, Gao Z, et al. Des-gamma-carboxy prothrombin antagonizes the effects of Sorafenib on human hepatocellular carcinoma through activation of the Raf/MEK/ERK and PI3K/Akt/mTOR signaling pathways. Oncotarget. 2016;7:36767-36782 pubmed publisher

product information

SKU :

4255S

Product-Name :

PI3 Kinase p110α Antibody

Size :

100 ul

Price-(USD) :

235 USD

Species-x-Reactivity :

H, M, R, (B)

Applications :

Immunoprecipitation

Product-Category :

PI3K / Akt Signaling

Shipping-Temp :

AMBIENT

Storage-Temp :

-20°C

Product-Type :

Polyclonal Antibody

MW :

110

Host :

Rabbit

Target :

PI3K p110 alpha

Primary-Protein :

PIK3CA

Alt-Names :

MGC142161,MGC142163,PI3-kinase p110 subunit alpha,PI3-kinase subunit alpha,PI3K,PI3K-alpha,PIK3CA,PK3CA,Phosphatidylinositol-4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha,Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform,PtdIns-3-kinase p110,PtdIns-3-kinase subunit alpha,PtdIns-3-kinase subunit p110-alpha,p110-alpha,phosphatidylinositol 3-kinase, catalytic, 110-KD, alpha,phosphatidylinositol 3-kinase, catalytic, alpha polypeptide,phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit, alpha isoform,phosphoinositide-3-kinase, catalytic, alpha polypeptide

more info or order :

Cell Signaling Technology product webpage