product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
TFEB Antibody
catalog :
4240S
quantity :
100 ul
price :
235 USD
clonality :
polyclonal
host :
rabbit
reactivity :
human, mouse
application :
western blot, immunocytochemistry, immunoprecipitation
citations: 6
Published Application/Species/DilutionReference
  • western blot (knockdown validation); human; 1:1000; fig 6
Medina D, Di Paola S, Peluso I, Armani A, De Stefani D, Venditti R, et al. Lysosomal calcium signalling regulates autophagy through calcineurin and ​TFEB. Nat Cell Biol. 2015;17:288-99 pubmed
  • western blot; mouse; fig 1
Wang H, Wang R, Carrera I, Xu S, Lakshmana M. TFEB Overexpression in the P301S Model of Tauopathy Mitigates Increased PHF1 Levels and Lipofuscin Puncta and Rescues Memory Deficits. Eneuro. 2016;3: pubmed publisher
  • western blot; human
  • immunocytochemistry; human
Settembre C, Medina D. TFEB and the CLEAR network. Methods Cell Biol. 2015;126:45-62 pubmed publisher
  • immunocytochemistry; human
  • western blot; human; fig 2c
Perera R, Stoykova S, Nicolay B, Ross K, Fitamant J, Boukhali M, et al. Transcriptional control of autophagy-lysosome function drives pancreatic cancer metabolism. Nature. 2015;524:361-5 pubmed publisher
Marin Zapata P, Beese C, Jünger A, Dalmasso G, Brady N, Hamacher-Brady A. Time course decomposition of cell heterogeneity in TFEB signaling states reveals homeostatic mechanisms restricting the magnitude and duration of TFEB responses to mTOR activity modulation. BMC Cancer. 2016;16:355 pubmed publisher
Lee H, Lee J, Park M, Hong Y, Marti H, Kim H, et al. Pathological roles of the VEGF/SphK pathway in Niemann-Pick type C neurons. Nat Commun. 2014;5:5514 pubmed publisher
product information
SKU :
4240S
Product-Name :
TFEB Antibody
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H
Applications :
Immunoprecipitation
Product-Category :
Translational Control
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
65-70
Host :
Rabbit
Target :
TFEB
Primary-Protein :
TFEB
Alt-Names :
ALPHATFEB,BHLHE35,Class E basic helix-loop-helix protein 35,T-cell transcription factor EB,TCFEB,TFEB,Transcription factor EB
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.