product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Tri-Methyl-Histone H3 (Lys27) (C36B11) Rabbit mAb (Sepharose Bead Conjugate)
catalog :
4232
clonality :
monoclonal
host :
rabbit
conjugate :
Bead
clone name :
C36B11
reactivity :
human, mouse, rat
application :
immunoprecipitation
more info or order :
Cell Signaling Technology product webpage
citations: 8
Reference
Watson M, Hedley D. Whole blood measurement of histone modifications linked to the epigenetic regulation of gene expression. Curr Protoc Cytom. 2015;71:6.36.1-9 pubmed publisher
Theisen E, Gajiwala S, Bearss J, Sorna V, Sharma S, JANAT AMSBURY M. Reversible inhibition of lysine specific demethylase 1 is a novel anti-tumor strategy for poorly differentiated endometrial carcinoma. BMC Cancer. 2014;14:752 pubmed publisher
Oh E, Yang W, Cheong J, Choi S, Yoon S. Diffuse large B-cell lymphoma with histone H3 trimethylation at lysine 27: another poor prognostic phenotype independent of c-Myc/Bcl2 coexpression. Hum Pathol. 2014;45:2043-50 pubmed publisher
Riquelme E, Suraokar M, Behrens C, Lin H, Girard L, Nilsson M, et al. VEGF/VEGFR-2 upregulates EZH2 expression in lung adenocarcinoma cells and EZH2 depletion enhances the response to platinum-based and VEGFR-2-targeted therapy. Clin Cancer Res. 2014;20:3849-61 pubmed publisher
Liu Y, Platchek M, Kement B, Bee W, Truong M, Zeng X, et al. A novel approach applying a chemical biology strategy in phenotypic screening reveals pathway-selective regulators of histone 3 K27 tri-methylation. Mol Biosyst. 2014;10:251-7 pubmed publisher
Lee S, Phipson B, Hyland C, Leong H, Allan R, Lun A, et al. Polycomb repressive complex 2 (PRC2) suppresses E?-myc lymphoma. Blood. 2013;122:2654-63 pubmed publisher
Howard L, Mackenzie R, Pchelintsev N, McBryan T, McClure J, McBride M, et al. Profiling of transcriptional and epigenetic changes during directed endothelial differentiation of human embryonic stem cells identifies FOXA2 as a marker of early mesoderm commitment. Stem Cell Res Ther. 2013;4:36 pubmed publisher
Lee H, Yoon S, Jeong W, Kim H, Kim A, Kim B. Immunohistochemical analysis of polycomb group protein expression in advanced gastric cancer. Hum Pathol. 2012;43:1704-10 pubmed publisher
product information
SKU :
4232S
Product-Name :
Tri-Methyl-Histone H3 (Lys27) (C36B11) Rabbit mAb (Sepharose Bead Conjugate)
Size :
400 ul
Price-(USD) :
291 USD
Species-x-Reactivity :
H, M, R, Mk, (X, Z)
Applications :
Immunoprecipitation
Product-Category :
Chromatin Regulation / Nuclear Function
Shipping-Temp :
COLD
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
17
Host :
Rabbit
Target :
H3 (Lys28) trimethylate
Primary-Protein :
H3
Alt-Names :
H3 histone family, member A,H3/A,H31,H3FA,H3FB,H3FC,H3FD,H3FF,H3FH,H3FI,H3FJ,H3FK,H3FL,HIST1H3A,HIST1H3B,HIST1H3C,HIST1H3D,HIST1H3E,HIST1H3F,HIST1H3G,HIST1H3H,HIST1H3I,HIST1H3J,Histone H3.1,Histone H3/a,Histone H3/b,Histone H3/c,Histone H3/d,Histone H3/f,Histone H3/h,Histone H3/i,Histone H3/j,Histone H3/k,Histone H3/l,histone 1, H3a,histone cluster 1, H3a
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.