product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Tie2 (AB33) Mouse mAb
catalog :
4224
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
Ab33
reactivity :
human, mouse, bovine
application :
western blot, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
citations: 8
Published Application/Species/Sample/DilutionReference
  • western blot; human; fig 6c
Baganha F, de Jong R, Peters E, Voorham W, Jukema J, Delibegovic M, et al. Atorvastatin pleiotropically decreases intraplaque angiogenesis and intraplaque haemorrhage by inhibiting ANGPT2 release and VE-Cadherin internalization. Angiogenesis. 2021;24:567-581 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig s6a
  • western blot; human; 1:1000; loading ...; fig s11c
Zhou H, Qin L, Jiang Q, Murray K, Zhang H, Li B, et al. Caveolae-mediated Tie2 signaling contributes to CCM pathogenesis in a brain endothelial cell-specific Pdcd10-deficient mouse model. Nat Commun. 2021;12:504 pubmed publisher
  • immunocytochemistry; mouse; 1:100; loading ...; fig 3e
Ben Sasson A, Watson J, Sheffler W, Johnson M, Bittleston A, Somasundaram L, et al. Design of biologically active binary protein 2D materials. Nature. 2021;589:468-473 pubmed publisher
  • western blot; human; loading ...; fig s7b
Souma T, Thomson B, Heinen S, Carota I, Yamaguchi S, Onay T, et al. Context-dependent functions of angiopoietin 2 are determined by the endothelial phosphatase VEPTP. Proc Natl Acad Sci U S A. 2018;115:1298-1303 pubmed publisher
  • immunohistochemistry - paraffin section; human; fig 1I
Gravina G, Mancini A, Marampon F, Colapietro A, Delle Monache S, Sferra R, et al. The brain-penetrating CXCR4 antagonist, PRX177561, increases the antitumor effects of bevacizumab and sunitinib in preclinical models of human glioblastoma. J Hematol Oncol. 2017;10:5 pubmed publisher
  • immunohistochemistry - frozen section; human; 1:1000; loading ...; tbl 1
  • western blot; human; 1:1000; fig s4e
  • western blot; mouse; 1:1000; loading ...; fig 5i
Jenny Zhou H, Qin L, Zhang H, Tang W, Ji W, He Y, et al. Endothelial exocytosis of angiopoietin-2 resulting from CCM3 deficiency contributes to cerebral cavernous malformation. Nat Med. 2016;22:1033-1042 pubmed publisher
  • western blot; human; fig s3e
Warner M, Bridge K, Hewitson J, Hodgkinson M, Heyam A, Massa B, et al. S6K2-mediated regulation of TRBP as a determinant of miRNA expression in human primary lymphatic endothelial cells. Nucleic Acids Res. 2016;44:9942-9955 pubmed
  • western blot; human; fig 7
Dokun A, Chen L, Okutsu M, Farber C, Hazarika S, Jones W, et al. ADAM12: a genetic modifier of preclinical peripheral arterial disease. Am J Physiol Heart Circ Physiol. 2015;309:H790-803 pubmed publisher
product information
SKU :
4224S
Product-Name :
Tie2 (AB33) Mouse mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, B
Applications :
Immunoprecipitation
Product-Category :
RTK
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
160
Host :
Mouse
Target :
Tie2
Primary-Protein :
TIE2
Alt-Names :
Angiopoietin-1 receptor,CD202B,TEK,TEK tyrosine kinase, endothelial,TIE-2,TIE2,Tunica interna endothelial cell kinase,Tyrosine-protein kinase receptor TEK,Tyrosine-protein kinase receptor TIE-2,VMCM,VMCM1,hTIE2,p140 TEK,soluble TIE2 variant 1,soluble TIE2 variant 2
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.