product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Parkin (Prk8) Mouse mAb
catalog :
4211S
quantity :
100 ul
price :
235 USD
clonality :
monoclonal
host :
mouse
clone name :
Prk8
reactivity :
, human, mouse, rat
application :
western blot, immunoprecipitation
more info or order :
Cell Signaling Technology product webpage
citations: 8
Published Application/Species/DilutionReference
  • western blot; mouse; 1:1000
Kubli D, Cortez M, Moyzis A, Najor R, Lee Y, Gustafsson A. PINK1 Is Dispensable for Mitochondrial Recruitment of Parkin and Activation of Mitophagy in Cardiac Myocytes. PLoS ONE. 2015;10:e0130707 pubmed publisher
  • western blot; rat; 1:1000
Killinger B, Shah M, Moszczynska A. Co-administration of betulinic acid and methamphetamine causes toxicity to dopaminergic and serotonergic nerve terminals in the striatum of late adolescent rats. J Neurochem. 2014;128:764-75 pubmed publisher
Lee S, Zhang C, Liu X. Role of glucose metabolism and ATP in maintaining PINK1 levels during Parkin-mediated mitochondrial damage responses. J Biol Chem. 2015;290:904-17 pubmed publisher
Sargsyan A, Cai J, Fandino L, Labasky M, Forostyan T, Colosimo L, et al. Rapid parallel measurements of macroautophagy and mitophagy in mammalian cells using a single fluorescent biosensor. Sci Rep. 2015;5:12397 pubmed publisher
Brot S, Auger C, Bentata R, Rogemond V, Ménigoz S, Chounlamountri N, et al. Collapsin response mediator protein 5 (CRMP5) induces mitophagy, thereby regulating mitochondrion numbers in dendrites. J Biol Chem. 2014;289:2261-76 pubmed publisher
von Coelln R, Thomas B, Andrabi S, Lim K, Savitt J, Saffary R, et al. Inclusion body formation and neurodegeneration are parkin independent in a mouse model of alpha-synucleinopathy. J Neurosci. 2006;26:3685-96 pubmed
Wang D, Garden G, Kinoshita C, Wyles C, Babazadeh N, Sopher B, et al. Declines in Drp1 and parkin expression underlie DNA damage-induced changes in mitochondrial length and neuronal death. J Neurosci. 2013;33:1357-65 pubmed publisher
Cartelli D, Goldwurm S, Casagrande F, Pezzoli G, Cappelletti G. Microtubule destabilization is shared by genetic and idiopathic Parkinson's disease patient fibroblasts. PLoS ONE. 2012;7:e37467 pubmed publisher
product information
SKU :
4211S
Product-Name :
Parkin (Prk8) Mouse mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R
Applications :
Immunoprecipitation
Product-Category :
Neuroscience
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
50
Host :
Mouse
Target :
parkin
Primary-Protein :
PARK2
Alt-Names :
AR-JP,E3 ubiquitin ligase,E3 ubiquitin-protein ligase parkin,LPRS2,PARK2,PDJ,PRKN,PRKN2,Parkinson disease (autosomal recessive, juvenile) 2, parkin,Parkinson disease protein 2,Parkinson juvenile disease protein 2,parkin,parkin 2
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.