product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Cleaved Caspase-1 (Asp297) (D57A2) Rabbit mAb
catalog :
4199S
quantity :
100 ul
price :
274 USD
clonality :
monoclonal
host :
rabbit
reactivity :
human
application :
western blot, immunoprecipitation
citations: 5
Published Application/Species/DilutionReference
  • western blot; human; fig 2A
Zhang M, Qi Y, Li H, Cui J, Dai L, Frank J, et al. AIM2 inflammasome mediates Arsenic-induced secretion of IL-1 β and IL-18. Oncoimmunology. 2016;5:e1160182 pubmed publisher
Migita K, Izumi Y, Jiuchi Y, Kozuru H, Kawahara C, Nakamura M, et al. Serum amyloid A induces NLRP-3-mediated IL-1β secretion in neutrophils. PLoS ONE. 2014;9:e96703 pubmed publisher
Okada M, Matsuzawa A, Yoshimura A, Ichijo H. The lysosome rupture-activated TAK1-JNK pathway regulates NLRP3 inflammasome activation. J Biol Chem. 2014;289:32926-36 pubmed publisher
Motani K, Kushiyama H, Imamura R, Kinoshita T, Nishiuchi T, Suda T. Caspase-1 protein induces apoptosis-associated speck-like protein containing a caspase recruitment domain (ASC)-mediated necrosis independently of its catalytic activity. J Biol Chem. 2011;286:33963-72 pubmed publisher
Migita K, Koga T, Satomura K, Izumi M, Torigoshi T, Maeda Y, et al. Serum amyloid A triggers the mosodium urate -mediated mature interleukin-1β production from human synovial fibroblasts. Arthritis Res Ther. 2012;14:R119 pubmed publisher
product information
SKU :
4199S
Product-Name :
Cleaved Caspase-1 (Asp297) (D57A2) Rabbit mAb
Size :
100 ul
Price-(USD) :
274 USD
Species-x-Reactivity :
H, (Mk)
Applications :
Immunoprecipitation
Product-Category :
Apoptosis
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
20, 22
Host :
Rabbit
Target :
Casp1 (p20) cleaved
Primary-Protein :
Casp1
Alt-Names :
CASP-1,CASP1,CASP1 nirs variant 1,Caspase-1,Caspase-1 subunit p10,Caspase-1 subunit p20,ICE,IL-1 beta-converting enzyme,IL-1BC,IL1B-convertase,IL1BC,IL1BCE,Interleukin-1 beta convertase,Interleukin-1 beta-converting enzyme,caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase),caspase 1, apoptosis-related cysteine protease (interleukin 1, beta, convertase),interleukin 1-B converting enzyme,interleukin 1-beta convertase,p45
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.