α-Synuclein (D37A6) XP® Rabbit mAb | Cell Signaling Technology 4179 product information

product summary

company name :

Cell Signaling Technology

product type :

antibody

product name :

α-Synuclein (D37A6) XP® Rabbit mAb

catalog :

4179

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

D37A6

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Cell Signaling Technology product webpage

citations: 15

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; mouse; 1:1000; loading ...; fig 2a	Suzuki G, Imura S, Hosokawa M, Katsumata R, Nonaka T, Hisanaga S, et al. α-synuclein strains that cause distinct pathologies differentially inhibit proteasome. elife. 2020;9: pubmed publisher
immunohistochemistry - frozen section; mouse; 1:100; loading ...; fig 4g immunohistochemistry; mouse; 1:100; loading ...; fig 6a	Bozic M, Caus M, Rodrigues Díez R, Pedraza N, Ruiz Ortega M, Garí E, et al. Protective role of renal proximal tubular alpha-synuclein in the pathogenesis of kidney fibrosis. Nat Commun. 2020;11:1943 pubmed publisher
immunocytochemistry; mouse; loading ...; fig 2f immunohistochemistry; mouse; loading ...; fig 1b western blot; mouse; loading ...; fig 2a	Zhang W, Zhou M, Lu W, Gong J, Gao F, Li Y, et al. CNTNAP4 deficiency in dopaminergic neurons initiates parkinsonian phenotypes. Theranostics. 2020;10:3000-3021 pubmed publisher
immunohistochemistry - frozen section; mouse; 1:500; loading ...	Song L, McMackin M, Nguyen A, Cortopassi G. Parkin deficiency accelerates consequences of mitochondrial DNA deletions and Parkinsonism. Neurobiol Dis. 2017;100:30-38 pubmed publisher
immunohistochemistry - paraffin section; mouse; 1:250; fig s1	Vingill S, Brockelt D, Lancelin C, Tatenhorst L, Dontcheva G, Preisinger C, et al. Loss of FBXO7 (PARK15) results in reduced proteasome activity and models a parkinsonism-like phenotype in mice. EMBO J. 2016;35:2008-25 pubmed publisher
immunohistochemistry - frozen section; mouse; 1:100; loading ...; fig 3c western blot; mouse; 1:1000; loading ...; fig s4b	Doucet Beaupré H, Gilbert C, Profes M, Chabrat A, Pacelli C, Giguère N, et al. Lmx1a and Lmx1b regulate mitochondrial functions and survival of adult midbrain dopaminergic neurons. Proc Natl Acad Sci U S A. 2016;113:E4387-96 pubmed publisher
immunocytochemistry; mouse; fig 2	Deleglise B, Magnifico S, Duplus E, Vaur P, Soubeyre V, Belle M, et al. Î²-amyloid induces a dying-back process and remote trans-synaptic alterations in a microfluidic-based reconstructed neuronal network. Acta Neuropathol Commun. 2014;2:145 pubmed publisher
	Takaichi Y, Chambers J, Inoue H, Ano Y, Takashima A, Nakayama H, et al. Phosphorylation and oligomerization of α-synuclein associated with GSK-3β activation in the rTg4510 mouse model of tauopathy. Acta Neuropathol Commun. 2020;8:86 pubmed publisher
	Elfarrash S, Jensen N, Ferreira N, Betzer C, Thevathasan J, Diekmann R, et al. Organotypic slice culture model demonstrates inter-neuronal spreading of alpha-synuclein aggregates. Acta Neuropathol Commun. 2019;7:213 pubmed publisher
	Terada M, Suzuki G, Nonaka T, Kametani F, Tamaoka A, Hasegawa M. The effect of truncation on prion-like properties of α-synuclein. J Biol Chem. 2018;293:13910-13920 pubmed publisher
	Ugras S, Daniels M, Fazelinia H, Gould N, Yocum A, Luk K, et al. Induction of the Immunoproteasome Subunit Lmp7 Links Proteostasis and Immunity in α-Synuclein Aggregation Disorders. EBioMedicine. 2018;31:307-319 pubmed publisher
	Wassouf Z, Hentrich T, Samer S, Rotermund C, Kahle P, Ehrlich I, et al. Environmental Enrichment Prevents Transcriptional Disturbances Induced by Alpha-Synuclein Overexpression. Front Cell Neurosci. 2018;12:112 pubmed publisher
	Migdalska Richards A, Wegrzynowicz M, Rusconi R, Deangeli G, Di Monte D, Spillantini M, et al. The L444P Gba1 mutation enhances alpha-synuclein induced loss of nigral dopaminergic neurons in mice. Brain. 2017;140:2706-2721 pubmed publisher
	Rabl R, Breitschaedel C, Flunkert S, Duller S, Amschl D, Neddens J, et al. Early start of progressive motor deficits in Line 61 ?-synuclein transgenic mice. BMC Neurosci. 2017;18:22 pubmed publisher
	Liu H, Lu S, Ho P, Tse H, Pang S, Kung M, et al. LRRK2 R1441G mice are more liable to dopamine depletion and locomotor inactivity. Ann Clin Transl Neurol. 2014;1:199-208 pubmed publisher

product information

SKU :

4179S

Product-Name :

α-Synuclein (D37A6) XP® Rabbit mAb

Size :

100 ul

Price-(USD) :

260 USD

Species-x-Reactivity :

M, R

Applications :

Immunofluorescence (Frozen)

Product-Category :

Neuroscience

Shipping-Temp :

AMBIENT

Storage-Temp :

-20°C

Product-Type :

Monoclonal Antibody

MW :

Host :

Rabbit

Target :

synuclein-alpha mouse

Primary-Protein :

SNCA

Alt-Names :

Alpha-synuclein,NACP,Non-A beta component of AD amyloid,Non-A4 component of amyloid precursor,SYUA,Snca,Syn,alpha SYN,alphaSYN,non-A4 component of amyloid,synuclein, alpha

more info or order :

Cell Signaling Technology product webpage