product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
EPAC2 (5B1) Mouse mAb
catalog :
4156
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
5B1
reactivity :
human, mouse, rat
application :
western blot, western blot knockout validation
citations: 5
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; mouse; fig 2
Hwang M, Go Y, Park J, Shin S, Song S, Oh B, et al. Epac2a-null mice exhibit obesity-prone nature more susceptible to leptin resistance. Int J Obes (Lond). 2017;41:279-288 pubmed publisher
  • western blot; human; loading ...; fig 4c
Quinn S, Graves S, Dains McGahee C, Friedman E, Hassan H, Witkowski P, et al. Adenylyl cyclase 3/adenylyl cyclase-associated protein 1 (CAP1) complex mediates the anti-migratory effect of forskolin in pancreatic cancer cells. Mol Carcinog. 2017;56:1344-1360 pubmed publisher
  • western blot; human; 1:2000
Kusama K, Yoshie M, Tamura K, Nakayama T, Nishi H, Isaka K, et al. The role of exchange protein directly activated by cyclic AMP 2-mediated calreticulin expression in the decidualization of human endometrial stromal cells. Endocrinology. 2014;155:240-8 pubmed publisher
Hoivik E, Witsoe S, Bergheim I, Xu Y, Jakobsson I, Tengholm A, et al. DNA methylation of alternative promoters directs tissue specific expression of Epac2 isoforms. PLoS ONE. 2013;8:e67925 pubmed publisher
Dzhura I, Chepurny O, Kelley G, Leech C, Roe M, Dzhura E, et al. Epac2-dependent mobilization of intracellular Ca²+ by glucagon-like peptide-1 receptor agonist exendin-4 is disrupted in ?-cells of phospholipase C-? knockout mice. J Physiol. 2010;588:4871-89 pubmed publisher
product information
SKU :
4156S
Product-Name :
EPAC2 (5B1) Mouse mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R
Applications :
Western blot
Product-Category :
Cytoskeletal Signaling
Shipping-Temp :
COLD
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
115
Host :
Mouse
Target :
RapGEF4 mouse
Primary-Protein :
RAPGEF4
Alt-Names :
1300003D15Rik,5730402K07Rik,6330581N18Rik,Cgef2,EPAC 2,Epac2,Exchange factor directly activated by cAMP 2,Exchange protein directly activated by cAMP 2,KIAA4040,OTTMUSP00000014141,RPGF4,Rap guanine nucleotide exchange factor (GEF) 4,Rap guanine nucleotide exchange factor 4,Rapgef4,cAMP-GEFII,cAMP-dependent Rap1 guanine-nucleotide exchange factor,cAMP-regulated guanine nucleotide exchange factor II,cAMP-regulated guanine nucleotide exchange factor IIB,mKIAA4040
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.