product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
EPAC1 (5D3) Mouse mAb
catalog :
4155
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
5D3
reactivity :
human, mouse, rat
application :
western blot
citations: 5
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 4c
Liu H, Mei F, Yang W, Wang H, Wong E, Cai J, et al. Epac1 inhibition ameliorates pathological angiogenesis through coordinated activation of Notch and suppression of VEGF signaling. Sci Adv. 2020;6:eaay3566 pubmed publisher
  • western blot; human; loading ...; fig 4c
Quinn S, Graves S, Dains McGahee C, Friedman E, Hassan H, Witkowski P, et al. Adenylyl cyclase 3/adenylyl cyclase-associated protein 1 (CAP1) complex mediates the anti-migratory effect of forskolin in pancreatic cancer cells. Mol Carcinog. 2017;56:1344-1360 pubmed publisher
  • western blot; human; 1:2000; fig 6a
Kusama K, Yoshie M, Tamura K, Nakayama T, Nishi H, Isaka K, et al. The role of exchange protein directly activated by cyclic AMP 2-mediated calreticulin expression in the decidualization of human endometrial stromal cells. Endocrinology. 2014;155:240-8 pubmed publisher
Valsecchi F, Konràd C, D Aurelio M, Ramos Espiritu L, Stepanova A, Burstein S, et al. Distinct intracellular sAC-cAMP domains regulate ER Ca2+ signaling and OXPHOS function. J Cell Sci. 2017;130:3713-3727 pubmed publisher
Jansen S, Poppinga W, de Jager W, Lezoualc h F, Cheng X, Wieland T, et al. Epac1 links prostaglandin E2 to ?-catenin-dependent transcription during epithelial-to-mesenchymal transition. Oncotarget. 2016;7:46354-46370 pubmed publisher
product information
SKU :
4155S
Product-Name :
EPAC1 (5D3) Mouse mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R
Applications :
Western blot
Product-Category :
Cytoskeletal Signaling
Shipping-Temp :
COLD
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
100
Host :
Mouse
Target :
Epac1
Primary-Protein :
Epac1
Alt-Names :
9330170P05Rik,CGEF1,EPAC,EPAC 1,EPAC1,Exchange factor directly activated by cAMP 1,Exchange protein directly activated by cAMP 1,HSU79275,MGC21410,RAPGEF3,RPGF3,Rap guanine nucleotide exchange factor (GEF) 3,Rap guanine nucleotide exchange factor 3,Rap1 guanine-nucleotide-exchange factor directly activated by cAMP,bcm910,cAMP-GEFI,cAMP-regulated guanine nucleotide exchange factor I
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.