product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
EGR1 (44D5) Rabbit mAb
catalog :
4154
clonality :
monoclonal
host :
rabbit
conjugate :
nonconjugated
clone name :
44D5
reactivity :
human, mouse, rat, cow
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, chromatin immunoprecipitation, western blot knockout validation
more info or order :
Cell Signaling Technology product webpage
citations: 7
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human; 1:400; loading ...; fig 7b
  • western blot; human; loading ...; fig 9d
  • western blot knockout validation; mouse; loading ...; fig 9b
Baer A, Lundberg L, Swales D, Waybright N, Pinkham C, Dinman J, et al. Venezuelan Equine Encephalitis Virus Induces Apoptosis through the Unfolded Protein Response Activation of EGR1. J Virol. 2016;90:3558-72 pubmed publisher
  • immunohistochemistry; mouse; 1:800; loading ...; fig s11d
Bugaj L, Sabnis A, Mitchell A, Garbarino J, Toettcher J, Bivona T, et al. Cancer mutations and targeted drugs can disrupt dynamic signal encoding by the Ras-Erk pathway. Science. 2018;361: pubmed publisher
Wu Y, Ma S, Xia Y, Lu Y, Xiao S, Cao Y, et al. Loss of GCN5 leads to increased neuronal apoptosis by upregulating E2F1- and Egr-1-dependent BH3-only protein Bim. Cell Death Dis. 2017;8:e2570 pubmed publisher
Bagot R, Parise E, Pena C, Zhang H, Maze I, Chaudhury D, et al. Ventral hippocampal afferents to the nucleus accumbens regulate susceptibility to depression. Nat Commun. 2015;6:7062 pubmed publisher
Contreras J, Palanichamy J, Tran T, Fernando T, Rodríguez Malavé N, Goswami N, et al. MicroRNA-146a modulates B-cell oncogenesis by regulating Egr1. Oncotarget. 2015;6:11023-37 pubmed
Sinclair C, Seddon B. Overlapping and asymmetric functions of TCR signaling during thymic selection of CD4 and CD8 lineages. J Immunol. 2014;192:5151-9 pubmed publisher
Day J, Childs D, Guzman Karlsson M, Kibe M, Moulden J, Song E, et al. DNA methylation regulates associative reward learning. Nat Neurosci. 2013;16:1445-52 pubmed publisher
product information
SKU :
4154S
Product-Name :
EGR1 (44D5) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, (B)
Applications :
Chromatin Immunoprecipitation
Product-Category :
Neuroscience
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
75
Host :
Rabbit
Target :
EGR1
Primary-Protein :
EGR1
Alt-Names :
AT225,EGR-1,EGR1,Early growth response protein 1,G0S30,KROX-24,KROX24,NGFI-A,Nerve growth factor-induced protein A,TIS8,Transcription factor ETR103,Transcription factor Zif268,ZIF-268,ZNF225,Zinc finger protein 225,Zinc finger protein Krox-24,early growth response 1
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.