| Published Application/Species/Dilution | Reference |
|---|
- western blot (knockdown validation); human; fig 1
| Noh H, Hah Y, Ha J, Kang M, Zada S, Rha S, et al. Regulation of the epithelial to mesenchymal transition and metastasis by Raf kinase inhibitory protein-dependent Notch1 activity. Oncotarget. 2016;7:4632-46 pubmed publisher |
- western blot; mouse; fig s2
| Carofino B, Ayanga B, Tracey L, Brooke-Bisschop T, Justice M. PRDM14 promotes RAG-dependent Notch1 driver mutations in mouse T-ALL. Biol Open. 2016;5:645-53 pubmed publisher |
- immunohistochemistry; human; 1:100; fig 4
| Drier Y, Cotton M, Williamson K, Gillespie S, Ryan R, Kluk M, et al. An oncogenic MYB feedback loop drives alternate cell fates in adenoid cystic carcinoma. Nat Genet. 2016;48:265-72 pubmed publisher |
- western blot; human; 1:500; fig 2, 3
| Tominaga A, Cai T, Takagi-Niidome S, Iwatsubo T, Tomita T. Conformational Changes in Transmembrane Domain 4 of Presenilin 1 Are Associated with Altered Amyloid-β 42 Production. J Neurosci. 2016;36:1362-72 pubmed publisher |
- western blot; mouse; 1:1000; fig 5
| Huang G, Yang X, Chen K, Xing J, Guo L, Zhu L, et al. Porf-2 Inhibits Neural Stem Cell Proliferation Through Wnt/β-Catenin Pathway by Its GAP Domain. Front Cell Neurosci. 2016;10:85 pubmed publisher |
- western blot; human; 1:1000; fig 5a
| Imai Y, Kobayashi Y, Inoshita T, Meng H, Arano T, Uemura K, et al. The Parkinson's Disease-Associated Protein Kinase LRRK2 Modulates Notch Signaling through the Endosomal Pathway. PLoS Genet. 2015;11:e1005503 pubmed publisher |
- western blot; human; 1:500
| Nguyen D, Rubinstein L, Takebe N, Miele L, Tomaszewski J, Ivy P, et al. Notch1 phenotype and clinical stage progression in non-small cell lung cancer. J Hematol Oncol. 2015;8:9 pubmed publisher |
- immunohistochemistry - frozen section; human; 1:100
- western blot; human; 1:800
| Lim K, Brandt W, Heth J, Muraszko K, Fan X, Bar E, et al. Lateral inhibition of Notch signaling in neoplastic cells. Oncotarget. 2015;6:1666-77 pubmed |
- western blot; mouse; fig 9a
| Xie C, Wei D, Zhao L, Marchetto S, Mei L, Borg J, et al. Erbin is a novel substrate of the Sag-βTrCP E3 ligase that regulates KrasG12D-induced skin tumorigenesis. J Cell Biol. 2015;209:721-37 pubmed publisher |
| Aydin I, Melamed R, Adams S, Castillo-Martin M, Demir A, Bryk D, et al. FBXW7 mutations in melanoma and a new therapeutic paradigm. J Natl Cancer Inst. 2014;106:dju107 pubmed publisher |
| Yoshida R, Nagata M, Nakayama H, Niimori-Kita K, Hassan W, Tanaka T, et al. The pathological significance of Notch1 in oral squamous cell carcinoma. Lab Invest. 2013;93:1068-81 pubmed publisher |
| Jegalian A, Bodo J, Hsi E. NOTCH1 intracellular domain immunohistochemistry as a diagnostic tool to distinguish T-lymphoblastic lymphoma from thymoma. Am J Surg Pathol. 2015;39:565-72 pubmed publisher |
| Rettig E, Chung C, Bishop J, Howard J, Sharma R, Li R, et al. Cleaved NOTCH1 Expression Pattern in Head and Neck Squamous Cell Carcinoma Is Associated with NOTCH1 Mutation, HPV Status, and High-Risk Features. Cancer Prev Res (Phila). 2015;8:287-95 pubmed publisher |
| South A, Purdie K, Watt S, Haldenby S, den Breems N, Dimon M, et al. NOTCH1 mutations occur early during cutaneous squamous cell carcinogenesis. J Invest Dermatol. 2014;134:2630-8 pubmed publisher |
| Zhang X, Yang B, Wang J, Mo X, Zhang J, Hua Z. FADD is essential for glucose uptake and survival of thymocytes. Biochem Biophys Res Commun. 2014;451:202-7 pubmed publisher |
| Arruga F, Gizdić B, Serra S, Vaisitti T, Ciardullo C, Coscia M, et al. Functional impact of NOTCH1 mutations in chronic lymphocytic leukemia. Leukemia. 2014;28:1060-70 pubmed publisher |
| Rowe M, Raithatha S, Shannon-Lowe C. Counteracting effects of cellular Notch and Epstein-Barr virus EBNA2: implications for stromal effects on virus-host interactions. J Virol. 2014;88:12065-76 pubmed publisher |
| Mezquita B, Mezquita J, Barrot C, Carvajal S, Pau M, Mezquita P, et al. A truncated-Flt1 isoform of breast cancer cells is upregulated by Notch and downregulated by retinoic acid. J Cell Biochem. 2014;115:52-61 pubmed publisher |
| Hagenbeek T, Wu X, Choy L, Sanchez-Irizarry C, Seshagiri S, Stinson J, et al. Murine Pten(-/-) T-ALL requires non-redundant PI3K/mTOR and DLL4/Notch1 signals for maintenance and γc/TCR signals for thymic exit. Cancer Lett. 2014;346:237-48 pubmed publisher |
| Tezgel A, González-Pérez G, Telfer J, Osborne B, Minter L, Tew G. Novel protein transduction domain mimics as nonviral delivery vectors for siRNA targeting NOTCH1 in primary human T cells. Mol Ther. 2013;21:201-9 pubmed publisher |
| Zhao J, Ma M, Ren H, Liu Z, Edelman M, Pan H, et al. Anti-HDGF targets cancer and cancer stromal stem cells resistant to chemotherapy. Clin Cancer Res. 2013;19:3567-76 pubmed publisher |
| Wang X, Yu H, Linnoila R, Li L, Li D, Mo B, et al. Musashi1 as a potential therapeutic target and diagnostic marker for lung cancer. Oncotarget. 2013;4:739-50 pubmed |
| Sakamoto K, Fujii T, Kawachi H, Miki Y, Omura K, Morita K, et al. Reduction of NOTCH1 expression pertains to maturation abnormalities of keratinocytes in squamous neoplasms. Lab Invest. 2012;92:688-702 pubmed publisher |
| Zheng W, Tammela T, Yamamoto M, Anisimov A, Holopainen T, Kaijalainen S, et al. Notch restricts lymphatic vessel sprouting induced by vascular endothelial growth factor. Blood. 2011;118:1154-62 pubmed publisher |
| Treanor L, Volanakis E, Zhou S, Lu T, Sherr C, Sorrentino B. Functional interactions between Lmo2, the Arf tumor suppressor, and Notch1 in murine T-cell malignancies. Blood. 2011;117:5453-62 pubmed publisher |
