product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-HSL (Ser563) Antibody
catalog :
4139
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
antigen modification :
phosphorylated
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry
citations: 13
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:1000; fig 3e
Gómez Valadés A, Pozo M, Varela L, Boudjadja M, Ramirez S, Chivite I, et al. Mitochondrial cristae-remodeling protein OPA1 in POMC neurons couples Ca2+ homeostasis with adipose tissue lipolysis. Cell Metab. 2021;: pubmed publisher
  • western blot; mouse; loading ...; fig 2i
Liu Y, Cong P, Zhang T, Wang R, Wang X, Liu J, et al. Plasmalogen attenuates the development of hepatic steatosis and cognitive deficit through mechanism involving p75NTR inhibition. Redox Biol. 2021;43:102002 pubmed publisher
  • western blot; mouse; loading ...; fig 3e
Zhang G, Li R, Li W, Yang S, Sun Q, Yin H, et al. Toll-like receptor 3 ablation prevented high-fat diet-induced obesity and metabolic disorder. J Nutr Biochem. 2021;95:108761 pubmed publisher
  • western blot; mouse; 1:1000; loading ...
Reilly S, Hung C, Ahmadian M, Zhao P, Keinan O, Gomez A, et al. Catecholamines suppress fatty acid re-esterification and increase oxidation in white adipocytes via STAT3. Nat Metab. 2020;2:620-634 pubmed publisher
  • western blot; mouse; loading ...; fig 6s2c
Marmol P, Krapacher F, Ibanez C. Control of brown adipose tissue adaptation to nutrient stress by the activin receptor ALK7. elife. 2020;9: pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 4a
Cederquist C, Lentucci C, Martinez Calejman C, Hayashi V, Orofino J, GUERTIN D, et al. Systemic insulin sensitivity is regulated by GPS2 inhibition of AKT ubiquitination and activation in adipose tissue. Mol Metab. 2017;6:125-137 pubmed publisher
  • western blot; human; fig 3
Christensen B, Nellemann B, Jørgensen J, Pedersen S, Jessen N. Erythropoietin does not activate erythropoietin receptor signaling or lipolytic pathways in human subcutaneous white adipose tissue in vivo. Lipids Health Dis. 2016;15:160 pubmed publisher
  • western blot; human; loading ...; fig 4d
Rittig N, Bach E, Thomsen H, Pedersen S, Nielsen T, Jørgensen J, et al. Regulation of Lipolysis and Adipose Tissue Signaling during Acute Endotoxin-Induced Inflammation: A Human Randomized Crossover Trial. PLoS ONE. 2016;11:e0162167 pubmed publisher
  • western blot; mouse; fig 3
Park J, Xu X, Cho S, Hur K, Lee M, Kersten S, et al. CREBH-FGF21 axis improves hepatic steatosis by suppressing adipose tissue lipolysis. Sci Rep. 2016;6:27938 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 1a
Albert V, Svensson K, Shimobayashi M, Colombi M, Munoz S, Jimenez V, et al. mTORC2 sustains thermogenesis via Akt-induced glucose uptake and glycolysis in brown adipose tissue. EMBO Mol Med. 2016;8:232-46 pubmed publisher
  • western blot; mouse
Lagarrigue S, Lopez Mejia I, Denechaud P, Escoté X, Castillo Armengol J, Jimenez V, et al. CDK4 is an essential insulin effector in adipocytes. J Clin Invest. 2016;126:335-48 pubmed publisher
Zheng Q, Lin J, Huang J, Zhang H, Zhang R, Zhang X, et al. Reconstitution of UCP1 using CRISPR/Cas9 in the white adipose tissue of pigs decreases fat deposition and improves thermogenic capacity. Proc Natl Acad Sci U S A. 2017;114:E9474-E9482 pubmed publisher
Carroll S, Zhang E, Wang B, Leclair K, Rahman A, Cohen D, et al. Adipocyte arrestin domain-containing 3 protein (Arrdc3) regulates uncoupling protein 1 (Ucp1) expression in white adipose independently of canonical changes in β-adrenergic receptor signaling. PLoS ONE. 2017;12:e0173823 pubmed publisher
product information
SKU :
4139S
Product-Name :
Phospho-HSL (Ser563) Antibody
Size :
100 ul
Price-(USD) :
274 USD
Species-x-Reactivity :
M, (H, R)
Applications :
Immunofluorescence (Immunocytochemistry)
Product-Category :
Metabolism
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
81, 83
Host :
Rabbit
Target :
HSL (Ser853) phosphate
Primary-Protein :
HSL
Alt-Names :
HSL,Hormone-sensitive lipase,LHS,LIPE,LIPS,hormone-sensitive lipase testicular isoform,lipase, hormone-sensitive
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.