product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Ape1 Antibody
catalog :
4128
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, reverse phase protein lysate microarray
more info or order :
Cell Signaling Technology product webpage
citations: 5
Published Application/Species/Sample/DilutionReference
  • western blot; rat; loading ...; fig 7f
  • western blot; human; loading ...; fig 1b
Gao R, Chakraborty A, Geater C, Pradhan S, Gordon K, Snowden J, et al. Mutant huntingtin impairs PNKP and ATXN3, disrupting DNA repair and transcription. elife. 2019;8: pubmed publisher
  • flow cytometry; human; fig 3
Nassour H, Wang Z, Saad A, Papaluca A, Brosseau N, Affar E, et al. Peroxiredoxin 1 interacts with and blocks the redox factor APE1 from activating interleukin-8 expression. Sci Rep. 2016;6:29389 pubmed publisher
  • reverse phase protein lysate microarray; mouse; fig s1.b,c
Gruosso T, Mieulet V, Cardon M, Bourachot B, Kieffer Y, Devun F, et al. Chronic oxidative stress promotes H2AX protein degradation and enhances chemosensitivity in breast cancer patients. EMBO Mol Med. 2016;8:527-49 pubmed publisher
  • western blot; human; loading ...; fig 3a
Preet R, Siddharth S, Satapathy S, Das S, Nayak A, Das D, et al. Chk1 inhibitor synergizes quinacrine mediated apoptosis in breast cancer cells by compromising the base excision repair cascade. Biochem Pharmacol. 2016;105:23-33 pubmed publisher
  • western blot; human
Chen J, Miller B, Furano A. Repair of naturally occurring mismatches can induce mutations in flanking DNA. elife. 2014;3:e02001 pubmed publisher
product information
SKU :
4128S
Product-Name :
Ape1 Antibody
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, (Mk)
Applications :
Immunofluorescence (Immunocytochemistry)
Product-Category :
Cell Cycle / Checkpoint Control
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
34
Host :
Rabbit
Target :
APE1
Primary-Protein :
APE1
Alt-Names :
AP endonuclease 1,AP endonuclease class I,AP lyase,APE,APE1,APEN,APEX,APEX nuclease,APEX nuclease (multifunctional DNA repair enzyme) 1,APEX1,APX,Apurinic-apyrimidinic endonuclease 1,DNA-(apurinic or apyrimidinic site) lyase,HAP1,Protein REF-1,REF1,apurinic/apyrimidinic (abasic) endonuclease,apurinic/apyrimidinic exonuclease,deoxyribonuclease (apurinic or apyrimidinic),multifunctional DNA repair enzyme,redox factor 1
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.