product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Beclin-1 (2A4) Mouse mAb
catalog :
4122
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
2A4
reactivity :
human, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation
citations: 8
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; rat; loading ...; fig 4a
  • western blot; rat; loading ...; fig 4b
  • immunocytochemistry; human; loading ...; fig 4d, 4e
  • western blot; human; loading ...; fig 4g
Li L, Li Q, Huang W, Han Y, Tan H, An M, et al. Dapagliflozin Alleviates Hepatic Steatosis by Restoring Autophagy via the AMPK-mTOR Pathway. Front Pharmacol. 2021;12:589273 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 6a
Silva M, Nandi G, Tentarelli S, Gurrell I, Jamier T, Lucente D, et al. Prolonged tau clearance and stress vulnerability rescue by pharmacological activation of autophagy in tauopathy neurons. Nat Commun. 2020;11:3258 pubmed publisher
  • western blot; human; fig 5d
Pei G, Buijze H, Liu H, Moura Alves P, Goosmann C, Brinkmann V, et al. The E3 ubiquitin ligase NEDD4 enhances killing of membrane-perturbing intracellular bacteria by promoting autophagy. Autophagy. 2017;13:2041-2055 pubmed publisher
  • western blot; human; loading ...; fig 5d
Kong P, Zhu X, Geng Q, Xia L, Sun X, Chen Y, et al. The microRNA-423-3p-Bim Axis Promotes Cancer Progression and Activates Oncogenic Autophagy in Gastric Cancer. Mol Ther. 2017;25:1027-1037 pubmed publisher
  • western blot; human; 1:1000; loading ...
Ranjan K, Pathak C. Expression of FADD and cFLIPL balances mitochondrial integrity and redox signaling to substantiate apoptotic cell death. Mol Cell Biochem. 2016;422:135-150 pubmed
  • western blot; human; 1:1000; fig 3
Song M, Wang Y, Shang Z, Liu X, Xie D, Wang Q, et al. Bystander autophagy mediated by radiation-induced exosomal miR-7-5p in non-targeted human bronchial epithelial cells. Sci Rep. 2016;6:30165 pubmed publisher
  • western blot; human; fig 2
Zou M, Zhu W, Wang L, Shi L, Gao R, Ou Y, et al. AEG-1/MTDH-activated autophagy enhances human malignant glioma susceptibility to TGF-β1-triggered epithelial-mesenchymal transition. Oncotarget. 2016;7:13122-38 pubmed publisher
  • western blot; human
Ma Y, Han W, Li J, Hu L, Zhou Y. Physalin B not only inhibits the ubiquitin-proteasome pathway but also induces incomplete autophagic response in human colon cancer cells in vitro. Acta Pharmacol Sin. 2015;36:517-27 pubmed publisher
product information
SKU :
4122S
Product-Name :
Beclin-1 (2A4) Mouse mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H
Applications :
Immunoprecipitation
Product-Category :
Autophagy
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
60
Host :
Mouse
Target :
Beclin 1
Primary-Protein :
beclin 1
Alt-Names :
ATG6,ATG6 autophagy related 6 homolog,BECN1,Beclin-1,Coiled-coil myosin-like BCL2-interacting protein,GT197,Protein GT197,VPS30,beclin 1 (coiled-coil, moesin-like BCL2 interacting protein),beclin 1 (coiled-coil, moesin-like BCL2-interacting protein),beclin 1, autophagy related,beclin1
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.