product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
HSL Antibody
catalog :
4107S
quantity :
100 ul
price :
235 USD
clonality :
polyclonal
host :
rabbit
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 25
Published Application/Species/DilutionReference
  • western blot; mouse; fig 4
Zhao W, Li A, Feng X, Hou T, Liu K, Liu B, et al. Metformin and resveratrol ameliorate muscle insulin resistance through preventing lipolysis and inflammation in hypoxic adipose tissue. Cell Signal. 2016;28:1401-1411 pubmed publisher
  • western blot; human; fig 3
Christensen B, Nellemann B, Jørgensen J, Pedersen S, Jessen N. Erythropoietin does not activate erythropoietin receptor signaling or lipolytic pathways in human subcutaneous white adipose tissue in vivo. Lipids Health Dis. 2016;15:160 pubmed publisher
  • western blot; human; 1:1000; fig 1
  • western blot; mouse
Iglesias J, Lamontagne J, Erb H, Gezzar S, Zhao S, Joly E, et al. Simplified assays of lipolysis enzymes for drug discovery and specificity assessment of known inhibitors. J Lipid Res. 2016;57:131-41 pubmed publisher
  • western blot; mouse
Ertunc M, Sikkeland J, Fenaroli F, Griffiths G, Daniels M, Cao H, et al. Secretion of fatty acid binding protein aP2 from adipocytes through a nonclassical pathway in response to adipocyte lipase activity. J Lipid Res. 2015;56:423-34 pubmed publisher
  • western blot; rat; 1:1,000
Macpherson R, Castelli L, Miotto P, Frendo-Cumbo S, Milburn A, Roy B, et al. A maternal high fat diet has long-lasting effects on skeletal muscle lipid and PLIN protein content in rat offspring at young adulthood. Lipids. 2015;50:205-17 pubmed publisher
  • western blot; mouse; 1:1000; fig 1
Zhou L, Park S, Xu L, Xia X, Ye J, Su L, et al. Insulin resistance and white adipose tissue inflammation are uncoupled in energetically challenged Fsp27-deficient mice. Nat Commun. 2015;6:5949 pubmed publisher
  • western blot; human
Bakke S, Feng Y, Nikolić N, Kase E, Moro C, Stensrud C, et al. Myotubes from severely obese type 2 diabetic subjects accumulate less lipids and show higher lipolytic rate than myotubes from severely obese non-diabetic subjects. PLoS ONE. 2015;10:e0119556 pubmed publisher
  • western blot; mouse; 1:1000
Crane J, Palanivel R, Mottillo E, Bujak A, Wang H, Ford R, et al. Inhibiting peripheral serotonin synthesis reduces obesity and metabolic dysfunction by promoting brown adipose tissue thermogenesis. Nat Med. 2015;21:166-72 pubmed publisher
  • western blot; mouse
Amrutkar M, Cansby E, Nuñez-Durán E, Pirazzi C, Ståhlman M, Stenfeldt E, et al. Protein kinase STK25 regulates hepatic lipid partitioning and progression of liver steatosis and NASH. FASEB J. 2015;29:1564-76 pubmed publisher
  • western blot; mouse; 1:1000; fig 4
Ye R, Holland W, Gordillo R, Wang M, Wang Q, Shao M, et al. Adiponectin is essential for lipid homeostasis and survival under insulin deficiency and promotes β-cell regeneration. elife. 2014;3: pubmed publisher
  • western blot; rat
Beaudoin M, Snook L, Arkell A, Stefanson A, Wan Z, Simpson J, et al. Novel effects of rosiglitazone on SMAD2 and SMAD3 signaling in white adipose tissue of diabetic rats. Obesity (Silver Spring). 2014;22:1632-42 pubmed publisher
  • western blot; mouse
Zhu H, Guariglia S, Li W, Brancho D, Wang Z, Scherer P, et al. Role of extracellular signal-regulated kinase 5 in adipocyte signaling. J Biol Chem. 2014;289:6311-22 pubmed publisher
  • western blot; mouse; 1:500
Jha P, Knopf A, Koefeler H, Mueller M, Lackner C, Hoefler G, et al. Role of adipose tissue in methionine-choline-deficient model of non-alcoholic steatohepatitis (NASH). Biochim Biophys Acta. 2014;1842:959-70 pubmed publisher
  • western blot; mouse
Lakeland T, Borg M, Matzaris M, Abdelkader A, Evans R, Watt M. Augmented expression and secretion of adipose-derived pigment epithelium-derived factor does not alter local angiogenesis or contribute to the development of systemic metabolic derangements. Am J Physiol Endocrinol Metab. 2014;306:E1367-77 pubmed publisher
  • western blot; mouse
Okumura T, Harada K, Oue K, Zhang J, Asano S, Hayashiuchi M, et al. Phospholipase C-related catalytically inactive protein (PRIP) regulates lipolysis in adipose tissue by modulating the phosphorylation of hormone-sensitive lipase. PLoS ONE. 2014;9:e100559 pubmed publisher
  • western blot; mouse; fig 4
Pulinilkunnil T, Kienesberger P, Nagendran J, Sharma N, Young M, Dyck J. Cardiac-specific adipose triglyceride lipase overexpression protects from cardiac steatosis and dilated cardiomyopathy following diet-induced obesity. Int J Obes (Lond). 2014;38:205-15 pubmed publisher
  • western blot; mouse
Castellani L, Root-McCaig J, Frendo-Cumbo S, Beaudoin M, Wright D. Exercise training protects against an acute inflammatory insult in mouse epididymal adipose tissue. J Appl Physiol (1985). 2014;116:1272-80 pubmed publisher
  • western blot; rat
Stephenson E, Lessard S, Rivas D, Watt M, Yaspelkis B, Koch L, et al. Exercise training enhances white adipose tissue metabolism in rats selectively bred for low- or high-endurance running capacity. Am J Physiol Endocrinol Metab. 2013;305:E429-38 pubmed publisher
  • western blot; mouse
De Sousa-Coelho A, Relat J, Hondares E, Pérez-Martí A, Ribas F, Villarroya F, et al. FGF21 mediates the lipid metabolism response to amino acid starvation. J Lipid Res. 2013;54:1786-97 pubmed publisher
  • immunohistochemistry - paraffin section; mouse
  • western blot; mouse
Martin S, Fernandez-Rojo M, Stanley A, Bastiani M, Okano S, Nixon S, et al. Caveolin-1 deficiency leads to increased susceptibility to cell death and fibrosis in white adipose tissue: characterization of a lipodystrophic model. PLoS ONE. 2012;7:e46242 pubmed publisher
Zhao X, Gao M, He J, Zou L, Lyu Y, Zhang L, et al. Perilipin1 deficiency in whole body or bone marrow-derived cells attenuates lesions in atherosclerosis-prone mice. PLoS ONE. 2015;10:e0123738 pubmed publisher
Cui X, Luan J, Ye J, Chen S. RGC32 deficiency protects against high-fat diet-induced obesity and insulin resistance in mice. J Endocrinol. 2015;224:127-37 pubmed publisher
Macpherson R, Vandenboom R, Roy B, Peters S. Skeletal muscle PLIN3 and PLIN5 are serine phosphorylated at rest and following lipolysis during adrenergic or contractile stimulation. Physiol Rep. 2013;1:e00084 pubmed
Loo L, Lin H, Singh D, Lyons K, Altschuler S, Wu L. Heterogeneity in the physiological states and pharmacological responses of differentiating 3T3-L1 preadipocytes. J Cell Biol. 2009;187:375-84 pubmed publisher
Aboulaich N, Chui P, Asara J, Flier J, Maratos-Flier E. Polymerase I and transcript release factor regulates lipolysis via a phosphorylation-dependent mechanism. Diabetes. 2011;60:757-65 pubmed publisher
product information
SKU :
4107S
Product-Name :
HSL Antibody
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
M, (H)
Applications :
Immunofluorescence (Immunocytochemistry)
Product-Category :
Metabolism
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
81, 83
Host :
Rabbit
Target :
HSL
Primary-Protein :
HSL
Alt-Names :
HSL,Hormone-sensitive lipase,LHS,LIPE,LIPS,hormone-sensitive lipase testicular isoform,lipase, hormone-sensitive
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.