product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
GEF-H1 (55B6) Rabbit mAb
catalog :
4076
clonality :
monoclonal
host :
rabbit
conjugate :
nonconjugated
clone name :
55B6
reactivity :
African green monkey, human, mouse, rat
application :
western blot, immunocytochemistry, immunoprecipitation
more info or order :
Cell Signaling Technology product webpage
citations: 8
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig s6a
Vassilev V, Platek A, Hiver S, Enomoto H, Takeichi M. Catenins Steer Cell Migration via Stabilization of Front-Rear Polarity. Dev Cell. 2017;43:463-479.e5 pubmed publisher
  • immunocytochemistry; mouse; loading ...; fig s8
  • western blot; mouse; 1:1000; loading ...; fig s8
  • western blot; African green monkey; 1:1000; loading ...; fig 6d
Takano T, Wu M, Nakamuta S, Naoki H, Ishizawa N, Namba T, et al. Discovery of long-range inhibitory signaling to ensure single axon formation. Nat Commun. 2017;8:33 pubmed publisher
  • immunoprecipitation; human; 1:1000; loading ...; fig 4c
  • western blot; human; 1:1000; loading ...; fig 4a
Jiu Y, Peranen J, Schaible N, Cheng F, Eriksson J, Krishnan R, et al. Vimentin intermediate filaments control actin stress fiber assembly through GEF-H1 and RhoA. J Cell Sci. 2017;130:892-902 pubmed publisher
  • western blot; human; fig 4
Scott D, Tolbert C, Burridge K. Tension on JAM-A activates RhoA via GEF-H1 and p115 RhoGEF. Mol Biol Cell. 2016;27:1420-30 pubmed publisher
  • western blot; human; 1:1000; fig s6
Heemskerk N, Schimmel L, Oort C, van Rijssel J, Yin T, Ma B, et al. F-actin-rich contractile endothelial pores prevent vascular leakage during leukocyte diapedesis through local RhoA signalling. Nat Commun. 2016;7:10493 pubmed publisher
Graessl M, Koch J, Calderon A, Kamps D, Banerjee S, Mazel T, et al. An excitable Rho GTPase signaling network generates dynamic subcellular contraction patterns. J Cell Biol. 2017;216:4271-4285 pubmed publisher
Osborne L, Li G, How T, O Brien E, Blobe G, Superfine R, et al. TGF-β regulates LARG and GEF-H1 during EMT to affect stiffening response to force and cell invasion. Mol Biol Cell. 2014;25:3528-40 pubmed publisher
Eitaki M, Yamamori T, Meike S, Yasui H, Inanami O. Vincristine enhances amoeboid-like motility via GEF-H1/RhoA/ROCK/Myosin light chain signaling in MKN45 cells. BMC Cancer. 2012;12:469 pubmed publisher
product information
SKU :
4076S
Product-Name :
GEF-H1 (55B6) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Hm, Mk
Applications :
Immunoprecipitation
Product-Category :
Cytoskeletal Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
120
Host :
Rabbit
Target :
GEF-H1
Primary-Protein :
ARHGEF2
Alt-Names :
ARHG2,ARHGEF2,DKFZp547L106,DKFZp547P1516,FLJ45440,GEF,GEF-H1,GEFH1,Guanine nucleotide exchange factor H1,KIAA0651,LFP40,Microtubule-regulated Rho-GEF,P40,Proliferating cell nucleolar antigen p40,Rho guanine nucleotide exchange factor 2,Rho/Rac guanine nucleotide exchange factor (GEF) 2,Rho/Rac guanine nucleotide exchange factor 2,RhoGEF2
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.