| Published Application/Species/Dilution | Reference |
|---|
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- western blot; mouse; 1:1000; fig s5
| Lee K, Lee H, Lin H, Tsay H, Tsai F, Shyue S, et al. Role of transient receptor potential ankyrin 1 channels in Alzheimer's disease. J Neuroinflammation. 2016;13:92 pubmed publisher |
- western blot; human; fig 5
| Huang J, Yao C, Chuang S, Yeh C, Lee L, Chen R, et al. Honokiol inhibits sphere formation and xenograft growth of oral cancer side population cells accompanied with JAK/STAT signaling pathway suppression and apoptosis induction. BMC Cancer. 2016;16:245 pubmed publisher |
- western blot; human; fig s3
- western blot; mouse; fig 3
| Yang Y, Andersson P, Hosaka K, Zhang Y, Cao R, Iwamoto H, et al. The PDGF-BB-SOX7 axis-modulated IL-33 in pericytes and stromal cells promotes metastasis through tumour-associated macrophages. Nat Commun. 2016;7:11385 pubmed publisher |
- western blot; human; fig 3
| Zhang Q, Wan M, Shi J, Horita D, Miller L, Kute T, et al. Yin Yang 1 promotes mTORC2-mediated AKT phosphorylation. J Mol Cell Biol. 2016;: pubmed |
- western blot; human; 1:1000; fig 7
| Joo M, Park J, Yoo H, Lee B, Chun H, Lee S, et al. The roles of HOXB7 in promoting migration, invasion and anti-apoptosis in gastric cancer. J Gastroenterol Hepatol. 2016;: pubmed publisher |
| Ronchi G, Haastert-Talini K, Fornasari B, Perroteau I, Geuna S, Gambarotta G. The Neuregulin1/ErbB system is selectively regulated during peripheral nerve degeneration and regeneration. Eur J Neurosci. 2016;43:351-64 pubmed publisher |
- western blot; human; fig 3
| Kline C, van den Heuvel A, Allen J, Prabhu V, Dicker D, El-Deiry W. ONC201 kills solid tumor cells by triggering an integrated stress response dependent on ATF4 activation by specific eIF2α kinases. Sci Signal. 2016;9:ra18 pubmed publisher |
- western blot; human; 1:1000; fig 3
- western blot; mouse; 1:1000; fig 1
| Takabatake Y, Oxvig C, Nagi C, Adelson K, Jaffer S, Schmidt H, et al. Lactation opposes pappalysin-1-driven pregnancy-associated breast cancer. EMBO Mol Med. 2016;8:388-406 pubmed publisher |
- western blot; human; 1:600; fig 6
| Huang Q, Zhan L, Cao H, Li J, Lyu Y, Guo X, et al. Increased mitochondrial fission promotes autophagy and hepatocellular carcinoma cell survival through the ROS-modulated coordinated regulation of the NFKB and TP53 pathways. Autophagy. 2016;:1-16 pubmed |
| Wu C, Niu L, Yan Z, Wang C, Liu N, Dai Y, et al. Pcdh11x Negatively Regulates Dendritic Branching. J Mol Neurosci. 2015;56:822-8 pubmed publisher |
- western blot; mouse; 1:1000
| Skarra D, Thackray V. FOXO1 is regulated by insulin and IGF1 in pituitary gonadotropes. Mol Cell Endocrinol. 2015;405:14-24 pubmed publisher |
- western blot; mouse; fig 1c
| Krishnan N, Krishnan K, Connors C, Choy M, Page R, Peti W, et al. PTP1B inhibition suggests a therapeutic strategy for Rett syndrome. J Clin Invest. 2015;125:3163-77 pubmed publisher |
| Seeßle J, Liebisch G, Schmitz G, Stremmel W, Chamulitrat W. Palmitate activation by fatty acid transport protein 4 as a model system for hepatocellular apoptosis and steatosis. Biochim Biophys Acta. 2015;1851:549-65 pubmed publisher |
- immunohistochemistry; human; 1:800
| Mundim F, Pasini F, Brentani M, Soares F, Nonogaki S, Waitzberg A. MYC is expressed in the stromal and epithelial cells of primary breast carcinoma and paired nodal metastases. Mol Clin Oncol. 2015;3:506-514 pubmed |
- immunohistochemistry - frozen section; mouse
- western blot; rat
| Li J, Xu Z, Jiang L, Mao J, Zeng Z, Fang L, et al. Rictor/mTORC2 protects against cisplatin-induced tubular cell death and acute kidney injury. Kidney Int. 2014;86:86-102 pubmed publisher |
- western blot; human; 1:1000; fig s1
| Ng Y, Lee J, Supko K, Khan A, Torres S, Berwick M, et al. Pan-erbB inhibition potentiates BRAF inhibitors for melanoma treatment. Melanoma Res. 2014;24:207-18 pubmed publisher |
| Bao Y, Cao X, Luo D, Sun R, Peng L, Wang L, et al. Urokinase-type plasminogen activator receptor signaling is critical in nasopharyngeal carcinoma cell growth and metastasis. Cell Cycle. 2014;13:1958-69 pubmed publisher |
- western blot; human; 1:200
| Chondrogiannis G, Kastamoulas M, Kanavaros P, Vartholomatos G, Bai M, Baltogiannis D, et al. Cytokine effects on cell viability and death of prostate carcinoma cells. Biomed Res Int. 2014;2014:536049 pubmed publisher |
- western blot; mouse; 1:200
| Cekanaviciute E, Fathali N, Doyle K, Williams A, Han J, Buckwalter M. Astrocytic transforming growth factor-beta signaling reduces subacute neuroinflammation after stroke in mice. Glia. 2014;62:1227-40 pubmed publisher |
- western blot; mouse; 1:1000; fig 4
| Gorman J, Liu S, Slopack D, Shariati K, Hasanee A, Olenich S, et al. Angiotensin II evokes angiogenic signals within skeletal muscle through co-ordinated effects on skeletal myocytes and endothelial cells. PLoS ONE. 2014;9:e85537 pubmed publisher |
- western blot; rat; 1:1000
| Kang E, Cho J. Effects of treadmill exercise on brain insulin signaling and β-amyloid in intracerebroventricular streptozotocin induced-memory impairment in rats. J Exerc Nutrition Biochem. 2014;18:89-96 pubmed publisher |
- western blot; human; 1:2000
| Nie C, Luo Y, Zhao X, Luo N, Tong A, Liu X, et al. Caspase-9 mediates Puma activation in UCN-01-induced apoptosis. Cell Death Dis. 2014;5:e1495 pubmed publisher |
| Liu J, Zheng L, Ma L, Wang B, Zhao Y, Wu N, et al. Oleanolic acid inhibits proliferation and invasiveness of Kras-transformed cells via autophagy. J Nutr Biochem. 2014;25:1154-60 pubmed publisher |
| Rai S, Tanaka H, Suzuki M, Ogoh H, Taniguchi Y, Morita Y, et al. Clathrin assembly protein CALM plays a critical role in KIT signaling by regulating its cellular transport from early to late endosomes in hematopoietic cells. PLoS ONE. 2014;9:e109441 pubmed publisher |
- western blot; mouse; 1:1000
| Majumder M, Xin X, Liu L, Girish G, Lala P. Prostaglandin E2 receptor EP4 as the common target on cancer cells and macrophages to abolish angiogenesis, lymphangiogenesis, metastasis, and stem-like cell functions. Cancer Sci. 2014;105:1142-51 pubmed publisher |
| Ito Y, Hart J, Ueno L, Vogt P. Oncogenic activity of the regulatory subunit p85β of phosphatidylinositol 3-kinase (PI3K). Proc Natl Acad Sci U S A. 2014;111:16826-9 pubmed publisher |
| Pereira L, Pinto R, Silva D, Moreira A, Beitzinger C, Oliveira P, et al. Intracellular trafficking of AIP56, an NF-κB-cleaving toxin from Photobacterium damselae subsp. piscicida. Infect Immun. 2014;82:5270-85 pubmed publisher |
- immunohistochemistry - paraffin section; human; 1:300
| Yarchoan M, Toledo J, Lee E, Arvanitakis Z, Kazi H, Han L, et al. Abnormal serine phosphorylation of insulin receptor substrate 1 is associated with tau pathology in Alzheimer's disease and tauopathies. Acta Neuropathol. 2014;128:679-89 pubmed publisher |
- western blot; mouse; fig 5
| Etnyre D, Stone A, Fong J, Jacobs R, Uppada S, Botting G, et al. Targeting c-Met in melanoma: mechanism of resistance and efficacy of novel combinatorial inhibitor therapy. Cancer Biol Ther. 2014;15:1129-41 pubmed publisher |
| Modi H, Cornu M, Thorens B. Glutamine stimulates biosynthesis and secretion of insulin-like growth factor 2 (IGF2), an autocrine regulator of beta cell mass and function. J Biol Chem. 2014;289:31972-82 pubmed publisher |
- western blot; human; 1:500
| Cheshenko N, Trepanier J, González P, Eugenin E, Jacobs W, Herold B. Herpes simplex virus type 2 glycoprotein H interacts with integrin αvβ3 to facilitate viral entry and calcium signaling in human genital tract epithelial cells. J Virol. 2014;88:10026-38 pubmed publisher |
| George S, Vishwamitra D, Manshouri R, Shi P, Amin H. The ALK inhibitor ASP3026 eradicates NPM-ALK⁺ T-cell anaplastic large-cell lymphoma in vitro and in a systemic xenograft lymphoma model. Oncotarget. 2014;5:5750-63 pubmed |
- western blot; human; 1:1000
| Gong F, Peng X, Sang Y, Qiu M, Luo C, He Z, et al. Dichloroacetate induces protective autophagy in LoVo cells: involvement of cathepsin D/thioredoxin-like protein 1 and Akt-mTOR-mediated signaling. Cell Death Dis. 2013;4:e913 pubmed publisher |
- western blot; human
- western blot; mouse
| Benoit Y, Witherspoon M, Laursen K, Guezguez A, Beauséjour M, Beaulieu J, et al. Pharmacological inhibition of polycomb repressive complex-2 activity induces apoptosis in human colon cancer stem cells. Exp Cell Res. 2013;319:1463-70 pubmed publisher |
| Yoshida R, Nagata M, Nakayama H, Niimori-Kita K, Hassan W, Tanaka T, et al. The pathological significance of Notch1 in oral squamous cell carcinoma. Lab Invest. 2013;93:1068-81 pubmed publisher |
- western blot; mouse; 1:200
| Busquets-Garcia A, Gomis-González M, Guegan T, Agustín-Pavón C, Pastor A, Mato S, et al. Targeting the endocannabinoid system in the treatment of fragile X syndrome. Nat Med. 2013;19:603-7 pubmed publisher |
| Mathew J, Loranger A, Gilbert S, Faure R, Marceau N. Keratin 8/18 regulation of glucose metabolism in normal versus cancerous hepatic cells through differential modulation of hexokinase status and insulin signaling. Exp Cell Res. 2013;319:474-86 pubmed publisher |
| Meng L, Kohn K, Pommier Y. Dose-response transition from cell cycle arrest to apoptosis with selective degradation of Mdm2 and p21WAF1/CIP1 in response to the novel anticancer agent, aminoflavone (NSC 686,288). Oncogene. 2007;26:4806-16 pubmed |
| Ohashi K, Nagata Y, Wada E, Zammit P, Shiozuka M, Matsuda R. Zinc promotes proliferation and activation of myogenic cells via the PI3K/Akt and ERK signaling cascade. Exp Cell Res. 2015;333:228-37 pubmed publisher |
| Goossens S, Radaelli E, Blanchet O, Durinck K, Van der Meulen J, Peirs S, et al. ZEB2 drives immature T-cell lymphoblastic leukaemia development via enhanced tumour-initiating potential and IL-7 receptor signalling. Nat Commun. 2015;6:5794 pubmed publisher |
| Chong M, Loh M, Thakkar B, Pang B, Iacopetta B, Soong R. Phosphatidylinositol-3-kinase pathway aberrations in gastric and colorectal cancer: meta-analysis, co-occurrence and ethnic variation. Int J Cancer. 2014;134:1232-8 pubmed publisher |
| Matsuda-Lennikov M, Suizu F, Hirata N, Hashimoto M, Kimura K, Nagamine T, et al. Lysosomal interaction of Akt with Phafin2: a critical step in the induction of autophagy. PLoS ONE. 2014;9:e79795 pubmed publisher |
| Miura H, Matsuda M, Aoki K. Development of a FRET biosensor with high specificity for Akt. Cell Struct Funct. 2014;39:9-20 pubmed |
| Badescu A, Couvelard A, Handra-Luca A. Akt pathway protein expression in gastrointestinal Kaposi sarcomas: relevance for tumor biology. APMIS. 2014;122:518-25 pubmed publisher |
| Wang M, Li F, Shi Z, Liu Y, Wang X, Li L, et al. N-cadherin is a novel ERα anchor that protects against 6-OHDA damage to dopaminergic cells. Cell Mol Neurobiol. 2014;34:123-31 pubmed publisher |
| García-Claver A, Lorente M, Mur P, Campos-Martin Y, Mollejo M, Velasco G, et al. Gene expression changes associated with erlotinib response in glioma cell lines. Eur J Cancer. 2013;49:1641-53 pubmed publisher |
| de la Cueva A, Ramirez de Molina A, Alvarez-Ayerza N, Ramos M, Cebrian A, del Pulgar T, et al. Combined 5-FU and ChoKα inhibitors as a new alternative therapy of colorectal cancer: evidence in human tumor-derived cell lines and mouse xenografts. PLoS ONE. 2013;8:e64961 pubmed publisher |
| Dzieran J, Fabian J, Feng T, Coulouarn C, Ilkavets I, Kyselova A, et al. Comparative analysis of TGF-β/Smad signaling dependent cytostasis in human hepatocellular carcinoma cell lines. PLoS ONE. 2013;8:e72252 pubmed publisher |
| Heaton J, Wood M, Kim A, Lima L, Barlaskar F, Almeida M, et al. Progression to adrenocortical tumorigenesis in mice and humans through insulin-like growth factor 2 and β-catenin. Am J Pathol. 2012;181:1017-33 pubmed publisher |
| Miura S, Kamiya S, Saito Y, Wada S, Hayashi R, Taira J, et al. Antiadhesive sites present in the fibronectin type III-like repeats of human plasma fibronectin. Biol Pharm Bull. 2007;30:891-7 pubmed |
| Reddiconto G, Toto C, Palamà I, De Leo S, de Luca E, De Matteis S, et al. Targeting of GSK3β promotes imatinib-mediated apoptosis in quiescent CD34+ chronic myeloid leukemia progenitors, preserving normal stem cells. Blood. 2012;119:2335-45 pubmed publisher |
| Gao D, Inuzuka H, Tan M, Fukushima H, Locasale J, Liu P, et al. mTOR drives its own activation via SCF(βTrCP)-dependent degradation of the mTOR inhibitor DEPTOR. Mol Cell. 2011;44:290-303 pubmed publisher |
| Wang L, Liu X, Wu Y, Wu W, Wu Y. Involvement of ROS in the inhibitory effect of thermotherapy combined with chemotherapy on A549 human lung adenocarcinoma cell growth through the Akt pathway. Oncol Rep. 2012;28:1369-75 pubmed publisher |
| Eliopoulos N, Zhao J, Bouchentouf M, Forner K, Birman E, Yuan S, et al. Human marrow-derived mesenchymal stromal cells decrease cisplatin renotoxicity in vitro and in vivo and enhance survival of mice post-intraperitoneal injection. Am J Physiol Renal Physiol. 2010;299:F1288-98 pubmed publisher |
