product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Fyn Antibody
catalog :
4023
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat, pigs
application :
western blot, immunocytochemistry, western blot knockout validation
citations: 13
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; mouse; loading ...; fig 1g
  • western blot; rat; loading ...; fig 1e
Won S, Incontro S, Nicoll R, Roche K. PSD-95 stabilizes NMDA receptors by inducing the degradation of STEP61. Proc Natl Acad Sci U S A. 2016;113:E4736-44 pubmed publisher
  • western blot; mouse; loading ...; fig 4b
Shiwaku H, Katayama S, Kondo K, Nakano Y, Tanaka H, Yoshioka Y, et al. Autoantibodies against NCAM1 from patients with schizophrenia cause schizophrenia-related behavior and changes in synapses in mice. Cell Rep Med. 2022;3:100597 pubmed publisher
  • western blot; mouse; loading ...; fig 2a
Amaral A, Perez Nievas B, Siao Tick Chong M, González Martínez A, Argente Escrig H, Rubio Guerra S, et al. Isoform-selective decrease of glycogen synthase kinase-3-beta (GSK-3β) reduces synaptic tau phosphorylation, transcellular spreading, and aggregation. iScience. 2021;24:102058 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig s4b
Tang S, Fesharaki Zadeh A, Takahashi H, Nies S, Smith L, Luo A, et al. Fyn kinase inhibition reduces protein aggregation, increases synapse density and improves memory in transgenic and traumatic Tauopathy. Acta Neuropathol Commun. 2020;8:96 pubmed publisher
  • western blot; human; loading ...; fig 7f
Timms R, Zhang Z, Rhee D, Harper J, Koren I, Elledge S. A glycine-specific N-degron pathway mediates the quality control of protein N-myristoylation. Science. 2019;365: pubmed publisher
  • immunocytochemistry; mouse; 1:500; loading ...; fig 4a
Padmanabhan P, Martínez Mármol R, Xia D, Götz J, Meunier F. Frontotemporal dementia mutant Tau promotes aberrant Fyn nanoclustering in hippocampal dendritic spines. elife. 2019;8: pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 2g
Salazar S, Cox T, Lee S, Brody A, Chyung A, Haas L, et al. Alzheimer's Disease Risk Factor Pyk2 Mediates Amyloid-β-Induced Synaptic Dysfunction and Loss. J Neurosci. 2019;39:758-772 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 6c
Kim H, Mun Y, Lee K, Park Y, Park J, Park J, et al. T cell microvilli constitute immunological synaptosomes that carry messages to antigen-presenting cells. Nat Commun. 2018;9:3630 pubmed publisher
  • western blot; pigs ; loading ...; fig 5j
  • western blot; human; fig 6a
Poulsen E, Iannuzzi F, Rasmussen H, Maier T, Enghild J, Jørgensen A, et al. An Aberrant Phosphorylation of Amyloid Precursor Protein Tyrosine Regulates Its Trafficking and the Binding to the Clathrin Endocytic Complex in Neural Stem Cells of Alzheimer's Disease Patients. Front Mol Neurosci. 2017;10:59 pubmed publisher
  • western blot; human; 1:200; fig st1
Treindl F, Ruprecht B, Beiter Y, Schultz S, Döttinger A, Staebler A, et al. A bead-based western for high-throughput cellular signal transduction analyses. Nat Commun. 2016;7:12852 pubmed publisher
  • western blot; human; fig 1
Subramaniam S, Ozdener M, Abdoul Azize S, Saito K, Malik B, Maquart G, et al. ERK1/2 activation in human taste bud cells regulates fatty acid signaling and gustatory perception of fat in mice and humans. FASEB J. 2016;30:3489-3500 pubmed
  • western blot; human; 1:3000; fig 8
Kii I, Sumida Y, Goto T, Sonamoto R, Okuno Y, Yoshida S, et al. Selective inhibition of the kinase DYRK1A by targeting its folding process. Nat Commun. 2016;7:11391 pubmed publisher
Tondera C, Laube M, Pietzsch J. Insights into binding of S100 proteins to scavenger receptors: class B scavenger receptor CD36 binds S100A12 with high affinity. Amino Acids. 2017;49:183-191 pubmed publisher
product information
SKU :
4023P
Product-Name :
Fyn Antibody
Size :
40 ul
Price-(USD) :
123 USD
Species-x-Reactivity :
H, M
Applications :
Western blot
Product-Category :
Immunology and Inflammation
Shipping-Temp :
COLD
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
59
Host :
Rabbit
Target :
Fyn
Primary-Protein :
Fyn
Alt-Names :
FYN,FYN oncogene related to SRC, FGR, YES,MGC45350,OKT3-induced calcium influx regulator,Proto-oncogene Syn,Proto-oncogene c-Fyn,SLK,SYN,Tyrosine-protein kinase Fyn,c-syn protooncogene,p59-Fyn,protein-tyrosine kinase fyn,proto-oncogene tyrosine-protein kinase fyn,src-like kinase,src/yes-related novel,tyrosine kinase p59fyn(T)
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.