product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
MMP-2 Antibody
catalog :
4022
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, other
citations: 25
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:1000; loading ...; fig 5a, 5c
Chen R, Sheng C, Ma R, Zhang L, Yang L, Chen Y. PLAC1 is an independent predictor of poor survival, and promotes cell proliferation and invasion in cervical cancer. Mol Med Rep. 2021;24: pubmed publisher
  • western blot; human; 1:1000; fig 3g
Zhang X, Huang Z, Wang J, Ma Z, Yang J, Corey E, et al. Targeting Feedforward Loops Formed by Nuclear Receptor RORγ and Kinase PBK in mCRPC with Hyperactive AR Signaling. Cancers (Basel). 2021;13: pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 2g: 2h, 2i
Li M, Wu P, Yang Z, Deng S, Ni L, Zhang Y, et al. miR-193a-5p promotes pancreatic cancer cell metastasis through SRSF6-mediated alternative splicing of OGDHL and ECM1. Am J Cancer Res. 2020;10:38-59 pubmed
  • western blot; human; loading ...; fig 2e
Kramer M, Markart P, Drakopanagiotakis F, Mamazhakypov A, Schaefer L, Didiasova M, et al. Pirfenidone inhibits motility of NSCLC cells by interfering with the urokinase system. Cell Signal. 2020;65:109432 pubmed publisher
  • western blot; human; 1:2000; fig 3b
Wu X, Chen S, Lu C. Amyloid precursor protein promotes the migration and invasion of breast cancer cells by regulating the MAPK signaling pathway. Int J Mol Med. 2019;: pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 4c
Yang L, Hong Q, Xu S, Kuang X, Di G, Liu G, et al. Downregulation of transgelin 2 promotes breast cancer metastasis by activating the reactive oxygen species/nuclear factor‑κB signaling pathway. Mol Med Rep. 2019;20:4045-4258 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 4a
Li Q, Youn J, Siu K, Murugesan P, Zhang Y, Cai H. Knockout of dihydrofolate reductase in mice induces hypertension and abdominal aortic aneurysm via mitochondrial dysfunction. Redox Biol. 2019;24:101185 pubmed publisher
  • other; human; loading ...; fig 4c
Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed publisher
  • western blot; human; 1:500; loading ...; fig 3D
Hu X, Zhang Z, Liang Z, Xie D, Zhang T, Yu D, et al. Downregulation of feline sarcoma-related protein inhibits cell migration, invasion and epithelial-mesenchymal transition via the ERK/AP-1 pathway in bladder urothelial cell carcinoma. Oncol Lett. 2017;13:686-694 pubmed publisher
  • western blot; human; loading ...; fig 7b
Sahu U, Choudhury A, Parvez S, Biswas S, Kar S. Induction of intestinal stemness and tumorigenicity by aberrant internalization of commensal non-pathogenic E. coli. Cell Death Dis. 2017;8:e2667 pubmed publisher
  • western blot; human; loading ...; fig 5e
Mandl M, Zhang S, Ulrich M, Schmoeckel E, Mayr D, Vollmar A, et al. Inhibition of Cdk5 induces cell death of tumor-initiating cells. Br J Cancer. 2017;116:912-922 pubmed publisher
  • western blot; human; loading ...; fig 3c
Xu J, Zhang X, Wang H, Ge S, Gao T, Song L, et al. HCRP1 downregulation promotes hepatocellular carcinoma cell migration and invasion through the induction of EGFR activation and epithelial-mesenchymal transition. Biomed Pharmacother. 2017;88:421-429 pubmed publisher
  • western blot; human; 1:800; loading ...; fig 3c
Gan J, Wang F, Mu D, Qu Y, Luo R, Wang Q. RNA interference targeting Aurora-A sensitizes glioblastoma cells to temozolomide chemotherapy. Oncol Lett. 2016;12:4515-4523 pubmed publisher
  • western blot; human; loading ...; fig s4a
Xiao B, Chen D, Luo S, Hao W, Jing F, Liu T, et al. Extracellular translationally controlled tumor protein promotes colorectal cancer invasion and metastasis through Cdc42/JNK/ MMP9 signaling. Oncotarget. 2016;7:50057-50073 pubmed publisher
  • western blot; mouse; fig 5
  • western blot; human; fig 1
Tsai S, Huang P, Hsu Y, Peng Y, Lee C, Wang J, et al. Inhibition of hypoxia inducible factor-1α attenuates abdominal aortic aneurysm progression through the down-regulation of matrix metalloproteinases. Sci Rep. 2016;6:28612 pubmed publisher
  • western blot; human; loading ...; fig 5a
Wang X, Wang N, Li H, Liu M, Cao F, Yu X, et al. Up-Regulation of PAI-1 and Down-Regulation of uPA Are Involved in Suppression of Invasiveness and Motility of Hepatocellular Carcinoma Cells by a Natural Compound Berberine. Int J Mol Sci. 2016;17:577 pubmed publisher
  • western blot; human; 1:1000; fig 3c
Liang H, Zhang Q, Lu J, Yang G, Tian N, Wang X, et al. MSX2 Induces Trophoblast Invasion in Human Placenta. PLoS ONE. 2016;11:e0153656 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 6a
Huang M, Liu T, Ma P, Mitteer R, Zhang Z, Kim H, et al. c-Met-mediated endothelial plasticity drives aberrant vascularization and chemoresistance in glioblastoma. J Clin Invest. 2016;126:1801-14 pubmed publisher
  • western blot; human; fig 4
  • western blot; mouse; fig 8
Shukla S, Sinha S, Khan S, Kumar S, Singh K, Mitra K, et al. Cucurbitacin B inhibits the stemness and metastatic abilities of NSCLC via downregulation of canonical Wnt/β-catenin signaling axis. Sci Rep. 2016;6:21860 pubmed publisher
  • western blot; human; 1:1000; fig 4
Liu T, Fang Z, Wang G, Shi M, Wang X, Jiang K, et al. Anti-tumor activity of the TRPM8 inhibitor BCTC in prostate cancer DU145 cells. Oncol Lett. 2016;11:182-188 pubmed
  • western blot; mouse; fig 1
  • western blot; human; fig 5
Eiseler T, Wille C, Koehler C, Illing A, Seufferlein T. Protein Kinase D2 Assembles a Multiprotein Complex at the Trans-Golgi Network to Regulate Matrix Metalloproteinase Secretion. J Biol Chem. 2016;291:462-77 pubmed publisher
  • western blot; human
Picot N, Guerrette R, Beauregard A, Jean S, Michaud P, Harquail J, et al. Mammaglobin 1 promotes breast cancer malignancy and confers sensitivity to anticancer drugs. Mol Carcinog. 2016;55:1150-62 pubmed publisher
Li W, Wu D, Niu Z, Jiang D, Ma H, He H, et al. 5-Azacytidine suppresses EC9706 cell proliferation and metastasis by upregulating the expression of SOX17 and CDH1. Int J Mol Med. 2016;38:1047-54 pubmed publisher
Nie X, Ou Yang J, Xing Y, Li D, Liu R, Xu R. Calycosin inhibits migration and invasion through modulation of transforming growth factor beta-mediated mesenchymal properties in U87 and U251 cells. Drug Des Devel Ther. 2016;10:767-79 pubmed publisher
Yang J, Lv X, Chen J, Xie C, Xia W, Jiang C, et al. CCL2-CCR2 axis promotes metastasis of nasopharyngeal carcinoma by activating ERK1/2-MMP2/9 pathway. Oncotarget. 2016;7:15632-47 pubmed publisher
product information
SKU :
4022S
Product-Name :
MMP-2 Antibody
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, (M, R)
Applications :
Western blot
Product-Category :
Adhesion/ECM
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
64, 72
Host :
Rabbit
Target :
MMP2
Primary-Protein :
MMP2
Alt-Names :
72 kDa gelatinase,72 kDa type IV collagenase,CLG4,CLG4A,Gelatinase A,MMP-2,MMP-II,MMP2,MONA,Matrix metalloproteinase-2,PEX,TBE-1,collagenase type IV-A,matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase),matrix metalloproteinase-II,neutrophil gelatinase
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.