product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-Troponin I (Cardiac) (Ser23/24) Antibody
catalog :
4004
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
antigen modification :
phosphorylated
reactivity :
human, mouse, rat
application :
western blot
citations: 21
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; loading ...; fig s2
Tanwar V, Gorr M, Velten M, Eichenseer C, Long V, Bonilla I, et al. In Utero Particulate Matter Exposure Produces Heart Failure, Electrical Remodeling, and Epigenetic Changes at Adulthood. J Am Heart Assoc. 2017;6: pubmed publisher
  • western blot; mouse; 1:2000; loading ...; fig 2c
Fu Q, Hu Y, Wang Q, Liu Y, Li N, Xu B, et al. High-fat diet induces protein kinase A and G-protein receptor kinase phosphorylation of β2 -adrenergic receptor and impairs cardiac adrenergic reserve in animal hearts. J Physiol. 2017;595:1973-1986 pubmed publisher
  • western blot; mouse; loading ...; fig 6
Ramratnam M, Salama G, Sharma R, Wang D, Smith S, Banerjee S, et al. Gene-Targeted Mice with the Human Troponin T R141W Mutation Develop Dilated Cardiomyopathy with Calcium Desensitization. PLoS ONE. 2016;11:e0167681 pubmed publisher
  • western blot; rat; 1:1000; loading ...; fig 1c
Scotcher J, Prysyazhna O, Boguslavskyi A, Kistamás K, Hadgraft N, Martin E, et al. Disulfide-activated protein kinase G I? regulates cardiac diastolic relaxation and fine-tunes the Frank-Starling response. Nat Commun. 2016;7:13187 pubmed publisher
  • western blot; mouse; 1:1000; fig 2a
Hammers D, Sleeper M, Forbes S, Shima A, Walter G, Sweeney H. Tadalafil Treatment Delays the Onset of Cardiomyopathy in Dystrophin-Deficient Hearts. J Am Heart Assoc. 2016;5: pubmed publisher
  • western blot; rat; fig 3
Qvit N, Joshi A, Cunningham A, Ferreira J, Mochly Rosen D. Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Protein-Protein Interaction Inhibitor Reveals a Non-catalytic Role for GAPDH Oligomerization in Cell Death. J Biol Chem. 2016;291:13608-21 pubmed publisher
  • western blot; rat; 1:1000; loading ...; fig 7a
Harvey T, Murphy R, Morrison J, Posterino G. Maternal Nutrient Restriction Alters Ca2+ Handling Properties and Contractile Function of Isolated Left Ventricle Bundles in Male But Not Female Juvenile Rats. PLoS ONE. 2015;10:e0138388 pubmed publisher
  • western blot; mouse; fig 3c
Guilbert A, Lim H, Cheng J, Wang Y. CaMKII-dependent myofilament Ca2+ desensitization contributes to the frequency-dependent acceleration of relaxation. Cell Calcium. 2015;58:489-99 pubmed publisher
  • western blot; mouse; fig 2
Pulinilkunnil T, Kienesberger P, Nagendran J, Sharma N, Young M, Dyck J. Cardiac-specific adipose triglyceride lipase overexpression protects from cardiac steatosis and dilated cardiomyopathy following diet-induced obesity. Int J Obes (Lond). 2014;38:205-15 pubmed publisher
  • western blot; mouse
Yi T, Vick J, Vecchio M, Begin K, Bell S, Delay R, et al. Identifying cellular mechanisms of zinc-induced relaxation in isolated cardiomyocytes. Am J Physiol Heart Circ Physiol. 2013;305:H706-15 pubmed publisher
  • western blot; mouse
Chang A, Huang J, Battiprolu P, Hill J, Kamm K, Stull J. The effects of neuregulin on cardiac Myosin light chain kinase gene-ablated hearts. PLoS ONE. 2013;8:e66720 pubmed publisher
Pai P, Kuo C, Ho T, Lin J, Lin D, Tsai F, et al. p53-mediated miR-18 repression activates HSF2 for IGF-IIR-dependent myocyte hypertrophy in hypertension-induced heart failure. Cell Death Dis. 2017;8:e2990 pubmed publisher
Chang A, Battiprolu P, Cowley P, Chen G, Gerard R, Pinto J, et al. Constitutive phosphorylation of cardiac myosin regulatory light chain in vivo. J Biol Chem. 2015;290:10703-16 pubmed publisher
Pugh S, MacDougall D, Agarwal S, Harvey R, Porter K, Calaghan S. Caveolin contributes to the modulation of basal and β-adrenoceptor stimulated function of the adult rat ventricular myocyte by simvastatin: a novel pleiotropic effect. PLoS ONE. 2014;9:e106905 pubmed publisher
Prasad V, Lorenz J, Lasko V, Nieman M, Al Moamen N, Shull G. Loss of the AE3 Cl(-)/HCO(-) 3 exchanger in mice affects rate-dependent inotropy and stress-related AKT signaling in heart. Front Physiol. 2013;4:399 pubmed publisher
Asp M, Martindale J, Metzger J. Direct, differential effects of tamoxifen, 4-hydroxytamoxifen, and raloxifene on cardiac myocyte contractility and calcium handling. PLoS ONE. 2013;8:e78768 pubmed publisher
Pires A, Pinho M, Alves B, Pinho S, Sena C, Seica R, et al. Reverse myocardial effects of intermedin in pressure-overloaded hearts: role of endothelial nitric oxide synthase activity. J Physiol. 2013;591:677-87 pubmed publisher
Charo D, Ho M, Fajardo G, Kawana M, Kundu R, Sheikh A, et al. Endogenous regulation of cardiovascular function by apelin-APJ. Am J Physiol Heart Circ Physiol. 2009;297:H1904-13 pubmed publisher
De Arcangelis V, Soto D, Xiang Y. Phosphodiesterase 4 and phosphatase 2A differentially regulate cAMP/protein kinase a signaling for cardiac myocyte contraction under stimulation of beta1 adrenergic receptor. Mol Pharmacol. 2008;74:1453-62 pubmed publisher
Palpant N, Day S, Herron T, Converso K, Metzger J. Single histidine-substituted cardiac troponin I confers protection from age-related systolic and diastolic dysfunction. Cardiovasc Res. 2008;80:209-18 pubmed publisher
Sumandea M, Rybin V, Hinken A, Wang C, Kobayashi T, Harleton E, et al. Tyrosine phosphorylation modifies protein kinase C delta-dependent phosphorylation of cardiac troponin I. J Biol Chem. 2008;283:22680-9 pubmed publisher
product information
SKU :
4004S
Product-Name :
Phospho-Troponin I (Cardiac) (Ser23/24) Antibody
Size :
100 ul
Price-(USD) :
274 USD
Species-x-Reactivity :
H, M, R
Applications :
Western blot
Product-Category :
Cytoskeletal Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
28
Host :
Rabbit
Target :
Troponin-1/TNNI3 (Ser23/Ser24) phosphate
Primary-Protein :
TNNI3
Alt-Names :
CMD1FF,CMD2A,CMH7,Cardiac troponin I,MGC116817,RCM1,TNNC1,TNNI3,Troponin I, cardiac muscle,cTnI,familial hypertrophic cardiomyopathy 7,troponin I type 3 (cardiac)
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.