product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Troponin I Antibody
catalog :
4002
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot
citations: 15
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:2000; loading ...; fig 2c
Fu Q, Hu Y, Wang Q, Liu Y, Li N, Xu B, et al. High-fat diet induces protein kinase A and G-protein receptor kinase phosphorylation of β2 -adrenergic receptor and impairs cardiac adrenergic reserve in animal hearts. J Physiol. 2017;595:1973-1986 pubmed publisher
  • western blot; rat; 1:1000; loading ...; fig 1c
Scotcher J, Prysyazhna O, Boguslavskyi A, Kistamás K, Hadgraft N, Martin E, et al. Disulfide-activated protein kinase G I? regulates cardiac diastolic relaxation and fine-tunes the Frank-Starling response. Nat Commun. 2016;7:13187 pubmed publisher
  • western blot; mouse; 1:2000; fig 5, 6
Tjondrokoesoemo A, Schips T, Kanisicak O, Sargent M, Molkentin J. Genetic overexpression of Serpina3n attenuates muscular dystrophy in mice. Hum Mol Genet. 2016;25:1192-202 pubmed publisher
De Winter J, Joureau B, Sequeira V, Clarke N, van der Velden J, Stienen G, et al. Effect of levosimendan on the contractility of muscle fibers from nemaline myopathy patients with mutations in the nebulin gene. Skelet Muscle. 2015;5:12 pubmed publisher
Baker J, Tyther R, Liebetrau C, Clark J, Howarth R, Patterson T, et al. Cardiac myosin-binding protein C: a potential early biomarker of myocardial injury. Basic Res Cardiol. 2015;110:23 pubmed publisher
Gineste C, Ottenheijm C, Le Fur Y, Banzet S, Pecchi E, Vilmen C, et al. Alterations at the cross-bridge level are associated with a paradoxical gain of muscle function in vivo in a mouse model of nemaline myopathy. PLoS ONE. 2014;9:e109066 pubmed publisher
Pugh S, MacDougall D, Agarwal S, Harvey R, Porter K, Calaghan S. Caveolin contributes to the modulation of basal and β-adrenoceptor stimulated function of the adult rat ventricular myocyte by simvastatin: a novel pleiotropic effect. PLoS ONE. 2014;9:e106905 pubmed publisher
Ciarapica R, Carcarino E, Adesso L, De Salvo M, Bracaglia G, Leoncini P, et al. Pharmacological inhibition of EZH2 as a promising differentiation therapy in embryonal RMS. BMC Cancer. 2014;14:139 pubmed publisher
Prasad V, Lorenz J, Lasko V, Nieman M, Al Moamen N, Shull G. Loss of the AE3 Cl(-)/HCO(-) 3 exchanger in mice affects rate-dependent inotropy and stress-related AKT signaling in heart. Front Physiol. 2013;4:399 pubmed publisher
Hu F, Koon C, Chan J, Lau K, Fung K. The cardioprotective effect of danshen and gegen decoction on rat hearts and cardiomyocytes with post-ischemia reperfusion injury. BMC Complement Altern Med. 2012;12:249 pubmed publisher
Pires A, Pinho M, Alves B, Pinho S, Sena C, Seica R, et al. Reverse myocardial effects of intermedin in pressure-overloaded hearts: role of endothelial nitric oxide synthase activity. J Physiol. 2013;591:677-87 pubmed publisher
Ku P, Chen L, Liang J, Cheng K, Li Y, Cheng J. Molecular role of GATA binding protein 4 (GATA-4) in hyperglycemia-induced reduction of cardiac contractility. Cardiovasc Diabetol. 2011;10:57 pubmed publisher
Charo D, Ho M, Fajardo G, Kawana M, Kundu R, Sheikh A, et al. Endogenous regulation of cardiovascular function by apelin-APJ. Am J Physiol Heart Circ Physiol. 2009;297:H1904-13 pubmed publisher
De Arcangelis V, Soto D, Xiang Y. Phosphodiesterase 4 and phosphatase 2A differentially regulate cAMP/protein kinase a signaling for cardiac myocyte contraction under stimulation of beta1 adrenergic receptor. Mol Pharmacol. 2008;74:1453-62 pubmed publisher
Sadayappan S, Finley N, Howarth J, Osinska H, Klevitsky R, Lorenz J, et al. Role of the acidic N' region of cardiac troponin I in regulating myocardial function. FASEB J. 2008;22:1246-57 pubmed
product information
SKU :
4002S
Product-Name :
Troponin I Antibody
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
M, (H, R, Pg)
Applications :
Western blot
Product-Category :
Cytoskeletal Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
28
Host :
Rabbit
Target :
Troponin-1/TNNI3
Primary-Protein :
TNNI3
Alt-Names :
CMD1FF,CMD2A,CMH7,Cardiac troponin I,MGC116817,RCM1,TNNC1,TNNI3,Troponin I, cardiac muscle,cTnI,familial hypertrophic cardiomyopathy 7,troponin I type 3 (cardiac)
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.