product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
LIN28A (A177) Antibody
catalog :
3978
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
white-tufted-ear marmoset, human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section
citations: 13
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; loading ...; fig 1b
Wang X, Li Q, Liu C, Hall P, Jiang J, Katchis C, et al. Lin28 Signaling Supports Mammalian PNS and CNS Axon Regeneration. Cell Rep. 2018;24:2540-2552.e6 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig s2
Govero J, Esakky P, Scheaffer S, Fernandez E, Drury A, Platt D, et al. Zika virus infection damages the testes in mice. Nature. 2016;540:438-442 pubmed publisher
  • western blot; human; loading ...; fig s2b
Powers J, Tsanov K, Pearson D, Roels F, Spina C, EBRIGHT R, et al. Multiple mechanisms disrupt the let-7 microRNA family in neuroblastoma. Nature. 2016;535:246-51 pubmed publisher
  • immunocytochemistry; white-tufted-ear marmoset; 1:70; fig 2
Debowski K, Warthemann R, Lentes J, Salinas Riester G, Dressel R, Langenstroth D, et al. Non-viral generation of marmoset monkey iPS cells by a six-factor-in-one-vector approach. PLoS ONE. 2015;10:e0118424 pubmed publisher
  • western blot; mouse
Thornton J, Du P, Jing L, Sjekloća L, Lin S, Grossi E, et al. Selective microRNA uridylation by Zcchc6 (TUT7) and Zcchc11 (TUT4). Nucleic Acids Res. 2014;42:11777-91 pubmed publisher
  • immunohistochemistry - paraffin section; human
Spence T, Sin Chan P, Picard D, Barszczyk M, Hoss K, Lu M, et al. CNS-PNETs with C19MC amplification and/or LIN28 expression comprise a distinct histogenetic diagnostic and therapeutic entity. Acta Neuropathol. 2014;128:291-303 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:100
  • immunocytochemistry; human; 1:100
  • western blot; human; 1:1000
Mao X, Hütt Cabezas M, Orr B, Weingart M, Taylor I, Rajan A, et al. LIN28A facilitates the transformation of human neural stem cells and promotes glioblastoma tumorigenesis through a pro-invasive genetic program. Oncotarget. 2013;4:1050-64 pubmed
Li M, Amaral P, Cheung P, Bergmann J, Kinoshita M, Kalkan T, et al. A lncRNA fine tunes the dynamics of a cell state transition involving Lin28, let-7 and de novo DNA methylation. elife. 2017;6: pubmed publisher
Fereydouni B, Salinas Riester G, Heistermann M, Dressel R, Lewerich L, Drummer C, et al. Long-Term Oocyte-Like Cell Development in Cultures Derived from Neonatal Marmoset Monkey Ovary. Stem Cells Int. 2016;2016:2480298 pubmed publisher
Aeckerle N, Drummer C, Debowski K, Viebahn C, Behr R. Primordial germ cell development in the marmoset monkey as revealed by pluripotency factor expression: suggestion of a novel model of embryonic germ cell translocation. Mol Hum Reprod. 2015;21:66-80 pubmed publisher
Fereydouni B, Drummer C, Aeckerle N, Schlatt S, Behr R. The neonatal marmoset monkey ovary is very primitive exhibiting many oogonia. Reproduction. 2014;148:237-47 pubmed publisher
Chang H, Martinez N, Thornton J, Hagan J, Nguyen K, Gregory R. Trim71 cooperates with microRNAs to repress Cdkn1a expression and promote embryonic stem cell proliferation. Nat Commun. 2012;3:923 pubmed publisher
Aeckerle N, Eildermann K, Drummer C, Ehmcke J, Schweyer S, Lerchl A, et al. The pluripotency factor LIN28 in monkey and human testes: a marker for spermatogonial stem cells?. Mol Hum Reprod. 2012;18:477-88 pubmed
product information
SKU :
3978S
Product-Name :
LIN28A (A177) Antibody
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, (Mk)
Applications :
Flow cytometry
Product-Category :
Developmental Biology
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
26
Host :
Rabbit
Target :
Lin28A
Primary-Protein :
LIN28A
Alt-Names :
CSDD1,FLJ12457,LIN-28,LIN28,LIN28A,LN28A,Lin-28A,Protein lin-28 homolog A,RNA-binding protein LIN-28,ZCCHC1,Zinc finger CCHC domain-containing protein 1,lin-28 homolog A (C. elegans),zinc finger, CCHC domain containing 1
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.