product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
GRB2 Antibody
catalog :
3972
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat, cow
application :
western blot
citations: 10
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; loading ...; fig s6a
Kuriakose J, Redecke V, Guy C, Zhou J, Wu R, Ippagunta S, et al. Patrolling monocytes promote the pathogenesis of early lupus-like glomerulonephritis. J Clin Invest. 2019;129:2251-2265 pubmed publisher
  • western blot; human; loading ...; fig 4c
Vaishnavi A, Schubert L, Rix U, Marek L, Le A, Keysar S, et al. EGFR Mediates Responses to Small-Molecule Drugs Targeting Oncogenic Fusion Kinases. Cancer Res. 2017;77:3551-3563 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 2a
Luo L, Bokil N, Wall A, Kapetanovic R, Lansdaal N, Marceline F, et al. SCIMP is a transmembrane non-TIR TLR adaptor that promotes proinflammatory cytokine production from macrophages. Nat Commun. 2017;8:14133 pubmed publisher
  • western blot; human; loading ...; fig 8
Liu L, Phua Y, Lee R, Ma X, Jenkins Y, Novy K, et al. Homo- and Heterotypic Association Regulates Signaling by the SgK269/PEAK1 and SgK223 Pseudokinases. J Biol Chem. 2016;291:21571-21583 pubmed
  • western blot; mouse; fig 5
Balakrishnan S, Niebert M, Richter D. Rescue of Cyclic AMP Mediated Long Term Potentiation Impairment in the Hippocampus of Mecp2 Knockout (Mecp2(-/y) ) Mice by Rolipram. Front Cell Neurosci. 2016;10:15 pubmed publisher
Ramirez U, Nikonova A, Liu H, Pecherskaya A, Lawrence S, Serebriiskii I, et al. Compounds identified by virtual docking to a tetrameric EGFR extracellular domain can modulate Grb2 internalization. BMC Cancer. 2015;15:436 pubmed publisher
Guo Y, Riley K, Iwasaki A, Steitz J. Alternative capture of noncoding RNAs or protein-coding genes by herpesviruses to alter host T cell function. Mol Cell. 2014;54:67-79 pubmed publisher
Gallaher A, Das S, Xiao Z, Andresson T, Kieffer Kwon P, Happel C, et al. Proteomic screening of human targets of viral microRNAs reveals functions associated with immune evasion and angiogenesis. PLoS Pathog. 2013;9:e1003584 pubmed publisher
Chaudhuri A, Xie M, Yang B, Mahapatra K, Liu J, Marsters S, et al. Distinct involvement of the Gab1 and Grb2 adaptor proteins in signal transduction by the related receptor tyrosine kinases RON and MET. J Biol Chem. 2011;286:32762-74 pubmed publisher
Benitez A, Dai Z, Mann H, Reeves R, Margineantu D, Gooley T, et al. Expression, signaling proficiency, and stimulatory function of the NKG2D lymphocyte receptor in human cancer cells. Proc Natl Acad Sci U S A. 2011;108:4081-6 pubmed publisher
product information
SKU :
3972S
Product-Name :
GRB2 Antibody
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Hm, Mk, B
Applications :
Western blot
Product-Category :
MAP Kinase Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
25
Host :
Rabbit
Target :
Grb2
Primary-Protein :
Grb2
Alt-Names :
ASH,Adapter protein GRB2,EGFRBP-GRB2,GRB2,Grb3-3,Growth factor receptor-bound protein 2,HT027,MST084,MSTP084,NCKAP2,Protein Ash,SH2/SH3 adapter GRB2,abundant SRC homology,epidermal growth factor receptor-binding protein GRB2,growth factor receptor-bound protein 3
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.