HDAC3 (7G6C5) Mouse mAb | Cell Signaling Technology 3949 product information

product summary

company name :

Cell Signaling Technology

product type :

antibody

product name :

HDAC3 (7G6C5) Mouse mAb

catalog :

3949

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

7G6C5

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry, immunoprecipitation, immunohistochemistry knockout validation

more info or order :

Cell Signaling Technology product webpage

citations: 11

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry knockout validation; mouse; fig S1a	Nott A, Cheng J, Gao F, Lin Y, Gjoneska E, Ko T, et al. Histone deacetylase 3 associates with MeCP2 to regulate FOXO and social behavior. Nat Neurosci. 2016;19:1497-1505 pubmed publisher
western blot; human; 1:1000; loading ...; fig s4a	Zhu Y, Wang G, Cingoz O, Goff S. NP220 mediates silencing of unintegrated retroviral DNA. Nature. 2018;564:278-282 pubmed publisher
western blot; human; loading ...; fig 6c	Hu B, Arpag S, Zuchner S, Li J. A novel missense mutation of CMT2P alters transcription machinery. Ann Neurol. 2016;80:834-845 pubmed publisher
western blot; rat; fig 5c	Lin Y, Warren C, Li J, McKinsey T, Russell B. Myofibril growth during cardiac hypertrophy is regulated through dual phosphorylation and acetylation of the actin capping protein CapZ. Cell Signal. 2016;28:1015-24 pubmed publisher
western blot; human; fig 7	Chaudhary S, Madhukrishna B, Adhya A, Keshari S, Mishra S. Overexpression of caspase 7 is ER? dependent to affect proliferation and cell growth in breast cancer cells by targeting p21(Cip). Oncogenesis. 2016;5:e219 pubmed publisher
immunocytochemistry; mouse; 1:100; loading ...; fig 7a western blot; mouse; 1:1000; loading ...; fig 1b	Leus N, van der Wouden P, van den Bosch T, Hooghiemstra W, Ourailidou M, Kistemaker L, et al. HDAC 3-selective inhibitor RGFP966 demonstrates anti-inflammatory properties in RAW 264.7 macrophages and mouse precision-cut lung slices by attenuating NF-κB p65 transcriptional activity. Biochem Pharmacol. 2016;108:58-74 pubmed publisher
western blot; human; 1:1000; fig 4	Liu X, Wang J, Li S, Li L, Huang M, Zhang Y, et al. Histone deacetylase 3 expression correlates with vasculogenic mimicry through the phosphoinositide3-kinaseÂ /Â ERK-MMP-laminin5Î³2 signaling pathway. Cancer Sci. 2015;106:857-66 pubmed publisher
western blot; mouse; 1:1000	Medford H, Porter K, Marsh S. Immediate effects of a single exercise bout on protein O-GlcNAcylation and chromatin regulation of cardiac hypertrophy. Am J Physiol Heart Circ Physiol. 2013;305:H114-23 pubmed publisher
	Gruber W, Peer E, Elmer D, Sternberg C, Tesanovic S, Del Burgo P, et al. Targeting class I histone deacetylases by the novel small molecule inhibitor 4SC-202 blocks oncogenic hedgehog-GLI signaling and overcomes smoothened inhibitor resistance. Int J Cancer. 2018;142:968-975 pubmed publisher
	Witt A, Lee C, Lee T, Azzam D, Wang B, Caslini C, et al. Identification of a cancer stem cell-specific function for the histone deacetylases, HDAC1 and HDAC7, in breast and ovarian cancer. Oncogene. 2017;36:1707-1720 pubmed publisher
	Li M, Riddle S, Frid M, El Kasmi K, McKinsey T, Sokol R, et al. Emergence of fibroblasts with a proinflammatory epigenetically altered phenotype in severe hypoxic pulmonary hypertension. J Immunol. 2011;187:2711-22 pubmed publisher

product information

SKU :

3949S

Product-Name :

HDAC3 (7G6C5) Mouse mAb

Size :

100 ul

Price-(USD) :

235 USD

Species-x-Reactivity :

H, M, R, Mk

Applications :

Immunofluorescence (Immunocytochemistry)

Product-Category :

Chromatin Regulation / Nuclear Function

Shipping-Temp :

COLD

Storage-Temp :

-20°C

Product-Type :

Monoclonal Antibody

MW :

Host :

Mouse

Target :

HDAC3

Primary-Protein :

HDAC3

Alt-Names :

HD3,HDAC3,Histone deacetylase 3,RPD3,RPD3-2,SMAP45

more info or order :

Cell Signaling Technology product webpage