| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot knockout validation; human; 1:1000; fig 2
| Haraguchi M, Sato M, Ozawa M. CRISPR/Cas9n-Mediated Deletion of the Snail 1Gene (SNAI1) Reveals Its Role in Regulating Cell Morphology, Cell-Cell Interactions, and Gene Expression in Ovarian Cancer (RMG-1) Cells. PLoS ONE. 2015;10:e0132260 pubmed publisher |
- western blot; human; loading ...; fig 5b
| Yang Y, Mei Q. Accumulation of AGO2 Facilitates Tumorigenesis of Human Hepatocellular Carcinoma. Biomed Res Int. 2020;2020:1631843 pubmed publisher |
- western blot; human; loading ...; fig 5a
| Li L, Yan S, Zhang H, Zhang M, Huang G, Chen M. Interaction of hnRNP K with MAP 1B-LC1 promotes TGF-β1-mediated epithelial to mesenchymal transition in lung cancer cells. BMC Cancer. 2019;19:894 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 3b, 4e
- western blot; human; 1:1000; loading ...; fig 3c
| Slocum E, Craig A, Villanueva A, Germain D. Parity predisposes breasts to the oncogenic action of PAPP-A and activation of the collagen receptor DDR2. Breast Cancer Res. 2019;21:56 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 4a, 4b, 4c
| Asnaghi L, White D, Key N, Choi J, Mahale A, Alkatan H, et al. ACVR1C/SMAD2 signaling promotes invasion and growth in retinoblastoma. Oncogene. 2019;38:2056-2075 pubmed publisher |
- other; human; loading ...; fig 4c
| Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed publisher |
- western blot; mouse; 1:1000; fig 5c
| Grasso S, Chapelle J, Salemme V, Aramu S, Russo I, Vitale N, et al. The scaffold protein p140Cap limits ERBB2-mediated breast cancer progression interfering with Rac GTPase-controlled circuitries. Nat Commun. 2017;8:14797 pubmed publisher |
- reverse phase protein lysate microarray; human; loading ...; fig st6
| Cherniack A, Shen H, Walter V, Stewart C, Murray B, Bowlby R, et al. Integrated Molecular Characterization of Uterine Carcinosarcoma. Cancer Cell. 2017;31:411-423 pubmed publisher |
- western blot; human; 1:2000; loading ...; fig 7a
| Kim N, Cha Y, Lee J, Lee S, Yang J, Yun J, et al. Snail reprograms glucose metabolism by repressing phosphofructokinase PFKP allowing cancer cell survival under metabolic stress. Nat Commun. 2017;8:14374 pubmed publisher |
- western blot; mouse; loading ...; fig 2d
| He Y, Northey J, Pelletier A, Kos Z, Meunier L, Haibe Kains B, et al. The Cdc42/Rac1 regulator CdGAP is a novel E-cadherin transcriptional co-repressor with Zeb2 in breast cancer. Oncogene. 2017;36:3490-3503 pubmed publisher |
- immunoprecipitation; human; loading ...; fig 1o
- western blot; human; 1:500; loading ...; fig 1i
| Liu T, Yu J, Deng M, Yin Y, Zhang H, Luo K, et al. CDK4/6-dependent activation of DUB3 regulates cancer metastasis through SNAIL1. Nat Commun. 2017;8:13923 pubmed publisher |
- western blot; human; loading ...; fig 3b
| Lee Y, Kim S, Song S, Hong H, Lee Y, Oh B, et al. Crosstalk between CCL7 and CCR3 promotes metastasis of colon cancer cells via ERK-JNK signaling pathways. Oncotarget. 2016;7:36842-36853 pubmed publisher |
- western blot; human; fig 4
| Kourtidis A, Anastasiadis P. PLEKHA7 defines an apical junctional complex with cytoskeletal associations and miRNA-mediated growth implications. Cell Cycle. 2016;15:498-505 pubmed publisher |
| Azzi S, Gallerne C, Romei C, Le Coz V, Gangemi R, Khawam K, et al. Human Renal Normal, Tumoral, and Cancer Stem Cells Express Membrane-Bound Interleukin-15 Isoforms Displaying Different Functions. Neoplasia. 2015;17:509-17 pubmed publisher |
- western blot; mouse; 1:1000
| Cicchini C, de Nonno V, Battistelli C, Cozzolino A, De Santis Puzzonia M, Ciafrè S, et al. Epigenetic control of EMT/MET dynamics: HNF4α impacts DNMT3s through miRs-29. Biochim Biophys Acta. 2015;1849:919-29 pubmed publisher |
- western blot; bovine
- western blot; dogs
| Izawa G, Kobayashi W, Haraguchi M, Sudo A, Ozawa M. The ectopic expression of Snail in MDBK cells does not induce epithelial-mesenchymal transition. Int J Mol Med. 2015;36:166-72 pubmed publisher |
| Perdigão Henriques R, Petrocca F, Altschuler G, Thomas M, Le M, Tan S, et al. miR-200 promotes the mesenchymal to epithelial transition by suppressing multiple members of the Zeb2 and Snail1 transcriptional repressor complexes. Oncogene. 2016;35:158-72 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 5b
| Liu Y, Han X, Gao B. Knockdown of S100A11 expression suppresses ovarian cancer cell growth and invasion. Exp Ther Med. 2015;9:1460-1464 pubmed |
- chromatin immunoprecipitation; human; fig 3
| Hsiao S, Chen M, Chen C, Chien M, Hua K, Hsiao M, et al. The H3K9 Methyltransferase G9a Represses E-cadherin and is Associated with Myometrial Invasion in Endometrial Cancer. Ann Surg Oncol. 2015;22 Suppl 3:S1556-65 pubmed publisher |
- chromatin immunoprecipitation; human
- EMSA; human
- western blot; human
| Lee M, Kim S, Kim B, Won C, Nam S, Kang S, et al. Snail1 induced in breast cancer cells in 3D collagen I gel environment suppresses cortactin and impairs effective invadopodia formation. Biochim Biophys Acta. 2014;1843:2037-54 pubmed publisher |
| Xia Y, Chang T, Wang Y, Liu Y, Li W, Li M, et al. YAP promotes ovarian cancer cell tumorigenesis and is indicative of a poor prognosis for ovarian cancer patients. PLoS ONE. 2014;9:e91770 pubmed publisher |
| Chen Y, Huang W, Chang S, Chang K, Kao S, Lo J, et al. Enhanced filopodium formation and stem-like phenotypes in a novel metastatic head and neck cancer cell model. Oncol Rep. 2013;30:2829-37 pubmed publisher |
- western blot; human; 1:1000
| Devine D, Rostas J, Metge B, Das S, Mulekar M, Tucker J, et al. Loss of N-Myc interactor promotes epithelial-mesenchymal transition by activation of TGF-?/SMAD signaling. Oncogene. 2014;33:2620-8 pubmed publisher |
| Chu I, Lai W, Aprelikova O, El Touny L, Kouros Mehr H, Green J. Expression of GATA3 in MDA-MB-231 triple-negative breast cancer cells induces a growth inhibitory response to TGFß. PLoS ONE. 2013;8:e61125 pubmed publisher |
| Yang J, Kim N, Yun J, Cho E, Cha Y, Cho S, et al. Snail augments fatty acid oxidation by suppression of mitochondrial ACC2 during cancer progression. Life Sci Alliance. 2020;3: pubmed publisher |
| Noce V, Battistelli C, Cozzolino A, Consalvi V, Cicchini C, Strippoli R, et al. YAP integrates the regulatory Snail/HNF4α circuitry controlling epithelial/hepatocyte differentiation. Cell Death Dis. 2019;10:768 pubmed publisher |
| Li Y, Hu Q, Li C, Liang K, Xiang Y, Hsiao H, et al. PTEN-induced partial epithelial-mesenchymal transition drives diabetic kidney disease. J Clin Invest. 2019;129:1129-1151 pubmed publisher |
| Hojo N, Huisken A, Wang H, Chirshev E, Kim N, Nguyen S, et al. Snail knockdown reverses stemness and inhibits tumour growth in ovarian cancer. Sci Rep. 2018;8:8704 pubmed publisher |
| Skrzypek K, Kusienicka A, Trzyna E, Szewczyk B, Ulman A, Konieczny P, et al. SNAIL is a key regulator of alveolar rhabdomyosarcoma tumor growth and differentiation through repression of MYF5 and MYOD function. Cell Death Dis. 2018;9:643 pubmed publisher |
| Wei Y, Kim T, Peng D, Duan D, Gibbons D, Yamauchi M, et al. Fibroblast-specific inhibition of TGF-?1 signaling attenuates lung and tumor fibrosis. J Clin Invest. 2017;127:3675-3688 pubmed publisher |
| Battistelli C, Cicchini C, Santangelo L, Tramontano A, Grassi L, Gonzalez F, et al. The Snail repressor recruits EZH2 to specific genomic sites through the enrollment of the lncRNA HOTAIR in epithelial-to-mesenchymal transition. Oncogene. 2017;36:942-955 pubmed publisher |
| Xiong S, Klausen C, Cheng J, Leung P. Activin B promotes endometrial cancer cell migration by down-regulating E-cadherin via SMAD-independent MEK-ERK1/2-SNAIL signaling. Oncotarget. 2016;7:40060-40072 pubmed publisher |
| Piotrowski Daspit A, Tien J, Nelson C. Interstitial fluid pressure regulates collective invasion in engineered human breast tumors via Snail, vimentin, and E-cadherin. Integr Biol (Camb). 2016;8:319-31 pubmed publisher |
| Asnaghi L, Gezgin G, Tripathy A, Handa J, Merbs S, van der Velden P, et al. EMT-associated factors promote invasive properties of uveal melanoma cells. Mol Vis. 2015;21:919-29 pubmed |
| Fisher M, Adhikary G, Xu W, Kerr C, Keillor J, Eckert R. Type II transglutaminase stimulates epidermal cancer stem cell epithelial-mesenchymal transition. Oncotarget. 2015;6:20525-39 pubmed |
| Qiu Y, Li W, Zhang H, Liu Y, Tian X, Fang W. P2X7 mediates ATP-driven invasiveness in prostate cancer cells. PLoS ONE. 2014;9:e114371 pubmed publisher |
| Kumar S, Kumar D, Raina K, Agarwal R, Agarwal C. Functional modification of adipocytes by grape seed extract impairs their pro-tumorigenic signaling on colon cancer stem cells and the daughter cancer cells. Oncotarget. 2014;5:10151-69 pubmed |
| Yen Y, Shiah S, Chu H, Hsu Y, Hsiao J, Chang J, et al. Reciprocal regulation of microRNA-99a and insulin-like growth factor I receptor signaling in oral squamous cell carcinoma cells. Mol Cancer. 2014;13:6 pubmed publisher |
| Chen Y, Pan H, Tseng H, Chu H, Hung Y, Yen Y, et al. Differentiated epithelial- and mesenchymal-like phenotypes in subcutaneous mouse xenografts using diffusion weighted-magnetic resonance imaging. Int J Mol Sci. 2013;14:21943-59 pubmed publisher |
| Lee S, Tsai C, Yu C, Chang Y. Elevated snail expression mediates tumor progression in areca quid chewing-associated oral squamous cell carcinoma via reactive oxygen species. PLoS ONE. 2013;8:e67985 pubmed publisher |
| Laird A, O Mahony F, Nanda J, Riddick A, O Donnell M, Harrison D, et al. Differential expression of prognostic proteomic markers in primary tumour, venous tumour thrombus and metastatic renal cell cancer tissue and correlation with patient outcome. PLoS ONE. 2013;8:e60483 pubmed publisher |
| Teixidó C, Mares R, Aracil M, Ramon Y Cajal S, Hernandez Losa J. Epithelial-mesenchymal transition markers and HER3 expression are predictors of elisidepsin treatment response in breast and pancreatic cancer cell lines. PLoS ONE. 2013;8:e53645 pubmed publisher |
| Lin Z, Chu H, Yen Y, Lewis B, Chen Y. Krüppel-like factor 4, a tumor suppressor in hepatocellular carcinoma cells reverts epithelial mesenchymal transition by suppressing slug expression. PLoS ONE. 2012;7:e43593 pubmed publisher |
| Park I, Son H, Che Z, Kim J. A novel gain-of-function mutation of TGF-? receptor II promotes cancer progression via delayed receptor internalization in oral squamous cell carcinoma. Cancer Lett. 2012;315:161-9 pubmed publisher |
