product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-Glycogen Synthase (Ser641) Antibody
catalog :
3891
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
antigen modification :
phosphorylated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunoprecipitation, immunohistochemistry - paraffin section, other
citations: 20
Published Application/Species/Sample/DilutionReference
  • western blot; rat; 1:1000; loading ...; fig 3b
Zhou X, Zhang R, Zou Z, Shen X, Xie T, Xu C, et al. Hypoglycaemic effects of glimepiride in sulfonylurea receptor 1 deficient rat. Br J Pharmacol. 2019;176:478-490 pubmed publisher
  • other; human; loading ...; fig 4c
Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed publisher
  • western blot; mouse; loading ...; fig 1a
Urbanska M, Gozdz A, Macias M, Cymerman I, Liszewska E, Kondratiuk I, et al. GSK3β Controls mTOR and Prosurvival Signaling in Neurons. Mol Neurobiol. 2018;55:6050-6062 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 5c
Krag T, Ruiz Ruiz C, Vissing J. Glycogen Synthesis in Glycogenin 1-Deficient Patients: A Role for Glycogenin 2 in Muscle. J Clin Endocrinol Metab. 2017;102:2690-2700 pubmed publisher
  • western blot; human; fig 5h
Zhao X, Sun K, Lan Z, Song W, Cheng L, Chi W, et al. Tenofovir and adefovir down-regulate mitochondrial chaperone TRAP1 and succinate dehydrogenase subunit B to metabolically reprogram glucose metabolism and induce nephrotoxicity. Sci Rep. 2017;7:46344 pubmed publisher
  • western blot; mouse; fig 4
Hinds T, Burns K, Hosick P, McBeth L, Nestor Kalinoski A, Drummond H, et al. Biliverdin Reductase A Attenuates Hepatic Steatosis by Inhibition of Glycogen Synthase Kinase (GSK) 3? Phosphorylation of Serine 73 of Peroxisome Proliferator-activated Receptor (PPAR) ?. J Biol Chem. 2016;291:25179-25191 pubmed
  • western blot; human
Weikel K, Cacicedo J, Ruderman N, Ido Y. Knockdown of GSK3β increases basal autophagy and AMPK signalling in nutrient-laden human aortic endothelial cells. Biosci Rep. 2016;36: pubmed publisher
  • western blot; mouse; loading ...; fig 1a
Krag T, Pinós T, Nielsen T, Duran J, García Rocha M, Andreu A, et al. Differential glucose metabolism in mice and humans affected by McArdle disease. Am J Physiol Regul Integr Comp Physiol. 2016;311:R307-14 pubmed publisher
  • western blot; mouse; 1:1000; fig 2
Plucińska K, Dekeryte R, Koss D, Shearer K, Mody N, Whitfield P, et al. Neuronal human BACE1 knockin induces systemic diabetes in mice. Diabetologia. 2016;59:1513-1523 pubmed publisher
  • western blot; mouse; fig 6a
Young P, Leonard S, Martin D, Findlay J. The effect of retinol binding protein on the proteome of C2C12 muscle cells. Diabetes Metab Res Rev. 2016;32:379-90 pubmed publisher
  • western blot; mouse
Irimia J, Tagliabracci V, Meyer C, Segvich D, DePaoli Roach A, Roach P. Muscle glycogen remodeling and glycogen phosphate metabolism following exhaustive exercise of wild type and laforin knockout mice. J Biol Chem. 2015;290:22686-98 pubmed publisher
  • western blot; mouse; 1:1000; fig 1
Cymerman I, Gozdz A, Urbanska M, Milek J, Dziembowska M, Jaworski J. Structural Plasticity of Dendritic Spines Requires GSK3α and GSK3β. PLoS ONE. 2015;10:e0134018 pubmed publisher
  • western blot; mouse; 1:1000; fig s9
Braccini L, Ciraolo E, Campa C, Perino A, Longo D, Tibolla G, et al. PI3K-C2γ is a Rab5 effector selectively controlling endosomal Akt2 activation downstream of insulin signalling. Nat Commun. 2015;6:7400 pubmed publisher
  • western blot; human; 1:1000; fig 3d
Janes K. An analysis of critical factors for quantitative immunoblotting. Sci Signal. 2015;8:rs2 pubmed publisher
  • western blot; human
Aguilera Ã, González Sancho J, Zazo S, Rincón R, Fernández A, Tapia O, et al. Nuclear DICKKOPF-1 as a biomarker of chemoresistance and poor clinical outcome in colorectal cancer. Oncotarget. 2015;6:5903-17 pubmed
  • western blot; human; fig 3c
Hunter R, Zeqiraj E, Morrice N, Sicheri F, Sakamoto K. Expression and purification of functional human glycogen synthase-1:glycogenin-1 complex in insect cells. Protein Expr Purif. 2015;108:23-29 pubmed publisher
Nicot A, Lo Verso F, Ratti F, Pilot Storck F, Streichenberger N, Sandri M, et al. Phosphorylation of NBR1 by GSK3 modulates protein aggregation. Autophagy. 2014;10:1036-53 pubmed publisher
Fuchs G, Diges C, Kohlstaedt L, Wehner K, Sarnow P. Proteomic analysis of ribosomes: translational control of mRNA populations by glycogen synthase GYS1. J Mol Biol. 2011;410:118-30 pubmed publisher
Chen C, Shaikenov T, Peterson T, Aimbetov R, Bissenbaev A, Lee S, et al. ER stress inhibits mTORC2 and Akt signaling through GSK-3?-mediated phosphorylation of rictor. Sci Signal. 2011;4:ra10 pubmed publisher
Wu G, Huang H, Garcia Abreu J, He X. Inhibition of GSK3 phosphorylation of beta-catenin via phosphorylated PPPSPXS motifs of Wnt coreceptor LRP6. PLoS ONE. 2009;4:e4926 pubmed publisher
product information
SKU :
3891S
Product-Name :
Phospho-Glycogen Synthase (Ser641) Antibody
Size :
100 ul
Price-(USD) :
274 USD
Species-x-Reactivity :
H, M, R
Applications :
Immunohistochemistry (Paraffin)
Product-Category :
Metabolism
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
85 to 90
Host :
Rabbit
Target :
Glycogen Synthase (Ser641) phosphate
Primary-Protein :
GYS1
Alt-Names :
GSY,GYS,GYS1,Glycogen [starch] synthase, muscle,glycogen synthase 1 (muscle)
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.