product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Snail (C15D3) Rabbit mAb
catalog :
3879P
quantity :
40 ul
price :
123 USD
clonality :
monoclonal
host :
rabbit
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 34
Published Application/Species/DilutionReference
  • immunocytochemistry (knockdown validation); human; fig 4
  • western blot (knockdown validation); human; 1:1000; fig 2
Osorio L, Farfán N, Castellon E, Contreras H. SNAIL transcription factor increases the motility and invasive capacity of prostate cancer cells. Mol Med Rep. 2016;13:778-86 pubmed publisher
  • western blot; human; fig 4
Kim D, Helfman D. Loss of MLCK leads to disruption of cell-cell adhesion and invasive behavior of breast epithelial cells via increased expression of EGFR and ERK/JNK signaling. Oncogene. 2016;: pubmed publisher
  • western blot; human; fig 2
Kuang J, Li L, Guo L, Su Y, Wang Y, Xu Y, et al. RNF8 promotes epithelial-mesenchymal transition of breast cancer cells. J Exp Clin Cancer Res. 2016;35:88 pubmed publisher
  • western blot; human; fig s7
Min K, Liggett J, Silva G, Wu W, Wang R, Shen R, et al. NAG-1/GDF15 accumulates in the nucleus and modulates transcriptional regulation of the Smad pathway. Oncogene. 2016;35:377-88 pubmed publisher
  • western blot; human; 1:1000; fig 3
Jiang S, Gao Y, Hou W, Liu R, Qi X, Xu X, et al. Sinomenine inhibits A549 human lung cancer cell invasion by mediating the STAT3 signaling pathway. Oncol Lett. 2016;12:1380-1386 pubmed
  • western blot; human
Duvall-Noelle N, Karwandyar A, Richmond A, Raman D. LASP-1: a nuclear hub for the UHRF1-DNMT1-G9a-Snail1 complex. Oncogene. 2016;35:1122-33 pubmed publisher
  • western blot; human; fig 7a
Yokdang N, Hatakeyama J, Wald J, Simion C, Tellez J, Chang D, et al. LRIG1 opposes epithelial-to-mesenchymal transition and inhibits invasion of basal-like breast cancer cells. Oncogene. 2016;35:2932-47 pubmed publisher
  • western blot; mouse; 1:1000; fig 6
Mehrabian M, Brethour D, Wang H, Xi Z, Rogaeva E, Schmitt-Ulms G. The Prion Protein Controls Polysialylation of Neural Cell Adhesion Molecule 1 during Cellular Morphogenesis. PLoS ONE. 2015;10:e0133741 pubmed publisher
  • western blot; human
Maity G, De A, Das A, Banerjee S, Sarkar S, Banerjee S. Aspirin blocks growth of breast tumor cells and tumor-initiating cells and induces reprogramming factors of mesenchymal to epithelial transition. Lab Invest. 2015;95:702-17 pubmed publisher
  • western blot; human; fig 4
Kawamura N, Nimura K, Nagano H, Yamaguchi S, Nonomura N, Kaneda Y. CRISPR/Cas9-mediated gene knockout of NANOG and NANOGP8 decreases the malignant potential of prostate cancer cells. Oncotarget. 2015;6:22361-74 pubmed
  • western blot; human; fig 1
Zhang Y, Wei X, Liang Y, Chen W, Zhang F, Bai J, et al. Over-Expressed Twist Associates with Markers of Epithelial Mesenchymal Transition and Predicts Poor Prognosis in Breast Cancers via ERK and Akt Activation. PLoS ONE. 2015;10:e0135851 pubmed publisher
  • western blot; human
  • immunocytochemistry; human; 1:100
Costabile V, Duraturo F, Delrio P, Rega D, Pace U, Liccardo R, et al. Lithium chloride induces mesenchymal‑to‑epithelial reverting transition in primary colon cancer cell cultures. Int J Oncol. 2015;46:1913-23 pubmed publisher
  • western blot; mouse; 1:1000; fig 6
Lin X, Xu W, Shao M, Fan Q, Wen G, Li C, et al. Shenling Baizhu San supresses colitis associated colorectal cancer through inhibition of epithelial-mesenchymal transition and myeloid-derived suppressor infiltration. BMC Complement Altern Med. 2015;15:126 pubmed publisher
  • western blot; human
Picot N, Guerrette R, Beauregard A, Jean S, Michaud P, Harquail J, et al. Mammaglobin 1 promotes breast cancer malignancy and confers sensitivity to anticancer drugs. Mol Carcinog. 2015;: pubmed publisher
  • western blot; human; 1:1000; fig 4
Wang H, Bao W, Jiang F, Che Q, Chen Z, Wang F, et al. Mutant p53 (p53-R248Q) functions as an oncogene in promoting endometrial cancer by up-regulating REGγ. Cancer Lett. 2015;360:269-79 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:100
Luo W, Yao K. Cancer stem cell characteristics, ALDH1 expression in the invasive front of nasopharyngeal carcinoma. Virchows Arch. 2014;464:35-43 pubmed publisher
  • western blot; human
Wu K, Chen K, Wang C, Jiao X, Wang L, Zhou J, et al. Cell fate factor DACH1 represses YB-1-mediated oncogenic transcription and translation. Cancer Res. 2014;74:829-39 pubmed publisher
  • western blot; human
Lu G, Zhang Q, Huang Y, Song J, Tomaino R, Ehrenberger T, et al. Phosphorylation of ETS1 by Src family kinases prevents its recognition by the COP1 tumor suppressor. Cancer Cell. 2014;26:222-34 pubmed publisher
  • western blot; human
Subramani R, Lopez-Valdez R, Arumugam A, Nandy S, Boopalan T, Lakshmanaswamy R. Targeting insulin-like growth factor 1 receptor inhibits pancreatic cancer growth and metastasis. PLoS ONE. 2014;9:e97016 pubmed publisher
  • western blot; human; 1:1000; fig 1a
Zhang P, Wei Y, Wang L, Debeb B, Yuan Y, Zhang J, et al. ATM-mediated stabilization of ZEB1 promotes DNA damage response and radioresistance through CHK1. Nat Cell Biol. 2014;16:864-75 pubmed publisher
Lu Z, Huang Q, Park J, Shen S, Lin L, Tokheim C, et al. Transcriptome-wide landscape of pre-mRNA alternative splicing associated with metastatic colonization. Mol Cancer Res. 2015;13:305-18 pubmed publisher
Lin X, Yi Z, Diao J, Shao M, Zhao L, Cai H, et al. ShaoYao decoction ameliorates colitis-associated colorectal cancer by downregulating proinflammatory cytokines and promoting epithelial-mesenchymal transition. J Transl Med. 2014;12:105 pubmed publisher
Lu J, Lee W, Kim M, Yun J, Jung J, Yi S, et al. The inhibitory effect of anthocyanins on Akt on invasion and epithelial-mesenchymal transition is not associated with the anti-EGFR effect of the anthocyanins. Int J Oncol. 2014;44:1756-66 pubmed publisher
Han Y, Ye J, Wu D, Wu P, Chen Z, Chen J, et al. LEIGC long non-coding RNA acts as a tumor suppressor in gastric carcinoma by inhibiting the epithelial-to-mesenchymal transition. BMC Cancer. 2014;14:932 pubmed publisher
Fujiki K, Inamura H, Matsuoka M. Detrimental effects of Notch1 signaling activated by cadmium in renal proximal tubular epithelial cells. Cell Death Dis. 2014;5:e1378 pubmed publisher
Knab L, Ebine K, Chow C, Raza S, Sahai V, Patel A, et al. Snail cooperates with Kras G12D in vivo to increase stem cell factor and enhance mast cell infiltration. Mol Cancer Res. 2014;12:1440-8 pubmed publisher
Naber H, Drabsch Y, Snaar-Jagalska B, Ten Dijke P, van Laar T. Snail and Slug, key regulators of TGF-β-induced EMT, are sufficient for the induction of single-cell invasion. Biochem Biophys Res Commun. 2013;435:58-63 pubmed publisher
Zheng X, Gai X, Wu Z, Liu Q, Yao Y. Metastasin leads to poor prognosis of hepatocellular carcinoma through partly inducing EMT. Oncol Rep. 2013;29:1811-8 pubmed publisher
Hanai J, Doro N, Seth P, Sukhatme V. ATP citrate lyase knockdown impacts cancer stem cells in vitro. Cell Death Dis. 2013;4:e696 pubmed publisher
Azab A, Hu J, Quang P, Azab F, Pitsillides C, Awwad R, et al. Hypoxia promotes dissemination of multiple myeloma through acquisition of epithelial to mesenchymal transition-like features. Blood. 2012;119:5782-94 pubmed publisher
Shih H, Sheen I, Su C, Peng W, Lin L, Wu J. Hepatitis D virus isolates with low replication and epithelial-mesenchymal transition-inducing activity are associated with disease remission. J Virol. 2012;86:9044-54 pubmed publisher
Tauler J, Zudaire E, Liu H, Shih J, Mulshine J. hnRNP A2/B1 modulates epithelial-mesenchymal transition in lung cancer cell lines. Cancer Res. 2010;70:7137-47 pubmed publisher
Ono H, Imoto I, Kozaki K, Tsuda H, Matsui T, Kurasawa Y, et al. SIX1 promotes epithelial-mesenchymal transition in colorectal cancer through ZEB1 activation. Oncogene. 2012;31:4923-34 pubmed publisher
Joost S, Almada L, Rohnalter V, Holz P, Vrabel A, Fernández-Barrena M, et al. GLI1 inhibition promotes epithelial-to-mesenchymal transition in pancreatic cancer cells. Cancer Res. 2012;72:88-99 pubmed publisher
product information
SKU :
3879P
Product-Name :
Snail (C15D3) Rabbit mAb
Size :
40 ul
Price-(USD) :
123 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Immunoprecipitation
Product-Category :
Developmental Biology
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
29
Host :
Rabbit
Target :
Snail
Primary-Protein :
Snail1
Alt-Names :
Protein sna,Protein snail homolog 1,SLUGH2,SNA,SNAH,SNAI1,Zinc finger protein SNAI1,dJ710H13.1,snail 1 homolog,snail 1 zinc finger protein,snail 1, zinc finger protein,snail homolog 1 (Drosophila)
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.