Snail (C15D3) Rabbit mAb | Cell Signaling Technology 3879 product information

product summary

company name :

Cell Signaling Technology

product type :

antibody

product name :

Snail (C15D3) Rabbit mAb

catalog :

3879

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

C15D3

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, ChIP-Seq, other

more info or order :

Cell Signaling Technology product webpage

citations: 165

Published Application/Species/Sample/Dilution	Reference
western blot; human; 1:1000; loading ...; fig 3i	Liu Q, Li H, Yang M, Mei Y, Niu T, Zhou Z, et al. Suppression of tumor growth and metastasis in Shkbp1 knockout mice. Cancer Gene Ther. 2022;29:709-721 pubmed publisher
western blot; human; loading ...; fig 5a	Jacquet M, Hervouet E, Baudu T, Herfs M, Parratte C, Feugeas J, et al. GABARAPL1 Inhibits EMT Signaling through SMAD-Tageted Negative Feedback. Biology (Basel). 2021;10: pubmed publisher
western blot; human; 1:1000; loading ...; fig 5a, 5c	Chen R, Sheng C, Ma R, Zhang L, Yang L, Chen Y. PLAC1 is an independent predictor of poor survival, and promotes cell proliferation and invasion in cervical cancer. Mol Med Rep. 2021;24: pubmed publisher
western blot; rat; fig 3f	Shi Y, Hu Y, Wang Y, Ma X, Tang L, Tao M, et al. Blockade of Autophagy Prevents the Development and Progression of Peritoneal Fibrosis. Front Pharmacol. 2021;12:724141 pubmed publisher
western blot; human; loading ...; fig 6a, 6b	Wang C, Yang Z, Xu E, Shen X, Wang X, Li Z, et al. Apolipoprotein C-II induces EMT to promote gastric cancer peritoneal metastasis via PI3K/AKT/mTOR pathway. Clin Transl Med. 2021;11:e522 pubmed publisher
western blot; human; loading ...; fig 4c	Wen J, Zhang G, Meng Y, Zhang L, Jiang M, Yu Z. RNA m6A methyltransferase METTL3 promotes colorectal cancer cell proliferation and invasion by regulating Snail expression. Oncol Lett. 2021;22:711 pubmed publisher
western blot; human; 1:1000; loading ...; fig 4g	Yu D, Yang X, Lin J, Cao Z, Lu C, Yang Z, et al. Super-Enhancer Induced IL-20RA Promotes Proliferation/Metastasis and Immune Evasion in Colorectal Cancer. Front Oncol. 2021;11:724655 pubmed publisher
western blot; human; 1:1000; loading ...; fig 4c, 4d	Zou J, Zhu X, Xiang D, Zhang Y, Li J, Su Z, et al. LIX1-like protein promotes liver cancer progression via miR-21-3p-mediated inhibition of fructose-1,6-bisphosphatase. Acta Pharm Sin B. 2021;11:1578-1591 pubmed publisher
immunohistochemistry; mouse; 1:500; loading ...; fig 1b	Scheibner K, Schirge S, Burtscher I, Büttner M, Sterr M, Yang D, et al. Epithelial cell plasticity drives endoderm formation during gastrulation. Nat Cell Biol. 2021;23:692-703 pubmed publisher
western blot; human; loading ...; fig 6d	Cheng X, Wang J, Liu C, Jiang T, Yang N, Liu D, et al. Zinc transporter SLC39A13/ZIP13 facilitates the metastasis of human ovarian cancer cells via activating Src/FAK signaling pathway. J Exp Clin Cancer Res. 2021;40:199 pubmed publisher
western blot; human; 1:1000; loading ...; fig 2b	Urdiciain A, Erausquin E, Zelaya M, Zazpe I, Lanciego J, Melendez B, et al. Silencing of Histone Deacetylase 6 Decreases Cellular Malignancy and Contributes to Primary Cilium Restoration, Epithelial-to-Mesenchymal Transition Reversion, and Autophagy Inhibition in Glioblastoma Cell Lines. Biology (Basel). 2021;10: pubmed publisher
western blot; mouse; 1:1000; loading ...; fig s10a	Wojnarowicz P, Escolano M, Huang Y, Desai B, Chin Y, Shah R, et al. Anti-tumor effects of an ID antagonist with no observed acquired resistance. NPJ Breast Cancer. 2021;7:58 pubmed publisher
western blot; mouse; 1:1000; loading ...; fig 4b	Xu Y, Pan S, Chen H, Qian H, Wang Z, Zhu X. MEX3A suppresses proliferation and EMT via inhibiting Akt signaling pathway in cervical cancer. Am J Cancer Res. 2021;11:1446-1462 pubmed
western blot; human; 1:1000; loading ...; fig 3a	Jiang Y, Han Q, Zhao H, Zhang J. Promotion of epithelial-mesenchymal transformation by hepatocellular carcinoma-educated macrophages through Wnt2b/β-catenin/c-Myc signaling and reprogramming glycolysis. J Exp Clin Cancer Res. 2021;40:13 pubmed publisher
western blot; human; 1:1000; loading ...	Jiang X, Xu Y, Ren H, Jiang J, Wudu M, Wang Q, et al. KLHL18 inhibits the proliferation, migration, and invasion of non-small cell lung cancer by inhibiting PI3K/PD-L1 axis activity. Cell Biosci. 2020;10:139 pubmed publisher
immunohistochemistry - paraffin section; human; 1:1000; loading ...; fig 1f immunoprecipitation; human; loading ...; fig 5i western blot; human; 1:1000; loading ...; fig 6a	Huang F, Zheng C, Huang L, Lin C, Wang J. USP18 directly regulates Snail1 protein through ubiquitination pathway in colorectal cancer. Cancer Cell Int. 2020;20:346 pubmed publisher
immunohistochemistry - paraffin section; human; 1:200; loading ...; fig 6e	Wang W, Wang H, Xiang L, Ni T, Jin F, Deng J, et al. DJ‑1 is a new prognostic marker and predicts chemotherapy efficacy in colorectal cancer. Oncol Rep. 2020;44:77-90 pubmed publisher
western blot; human; 1:1000; loading ...; fig 6a	Huang W, Yu D, Wang M, Han Y, Lin J, Wei D, et al. ITGBL1 promotes cell migration and invasion through stimulating the TGF-β signalling pathway in hepatocellular carcinoma. Cell Prolif. 2020;53:e12836 pubmed publisher
western blot; human; 1:1000; loading ...; fig 5l, 5m	Lin Z, Lin X, Zhu L, Huang J, Huang Y. TRIM2 directly deubiquitinates and stabilizes Snail1 protein, mediating proliferation and metastasis of lung adenocarcinoma. Cancer Cell Int. 2020;20:228 pubmed publisher
western blot; human; 1:1000; loading ...; fig 2h	Qi J, Liu S, Liu W, Cai G, Liao G. Identification of UAP1L1 as tumor promotor in gastric cancer through regulation of CDK6. Aging (Albany NY). 2020;12:6904-6927 pubmed publisher
western blot; human; loading ...; fig 2f	Chen J, Chen S, Zhuo L, Zhu Y, Zheng H. Regulation of cancer stem cell properties, angiogenesis, and vasculogenic mimicry by miR-450a-5p/SOX2 axis in colorectal cancer. Cell Death Dis. 2020;11:173 pubmed publisher
western blot; human; 1:1000; loading ...; fig 3d	Wang X, Shan Y, Tan Q, Tan C, Zhang H, Liu J, et al. MEX3A knockdown inhibits the development of pancreatic ductal adenocarcinoma. Cancer Cell Int. 2020;20:63 pubmed publisher
western blot; human; loading ...; fig 3c	Aldonza M, Ku J, Hong J, Kim D, Yu S, Lee M, et al. Prior acquired resistance to paclitaxel relays diverse EGFR-targeted therapy persistence mechanisms. Sci Adv. 2020;6:eaav7416 pubmed publisher
western blot; human; loading ...; fig 7d	Liu K, Yu Q, Li H, Xie C, Wu Y, Ma D, et al. BIRC7 promotes epithelial-mesenchymal transition and metastasis in papillary thyroid carcinoma through restraining autophagy. Am J Cancer Res. 2020;10:78-94 pubmed
western blot; human; 1:1000; loading ...; fig 2g: 2h, 2i	Li M, Wu P, Yang Z, Deng S, Ni L, Zhang Y, et al. miR-193a-5p promotes pancreatic cancer cell metastasis through SRSF6-mediated alternative splicing of OGDHL and ECM1. Am J Cancer Res. 2020;10:38-59 pubmed
western blot; mouse; loading ...; fig 4b	Rinastiti P, Ikeda K, Rahardini E, Miyagawa K, Tamada N, Kuribayashi Y, et al. Loss of family with sequence similarity 13, member A exacerbates pulmonary hypertension through accelerating endothelial-to-mesenchymal transition. PLoS ONE. 2020;15:e0226049 pubmed publisher
western blot; mouse; 1:1000; loading ...; fig 3h	Cheung E, DeNicola G, Nixon C, Blyth K, Labuschagne C, Tuveson D, et al. Dynamic ROS Control by TIGAR Regulates the Initiation and Progression of Pancreatic Cancer. Cancer Cell. 2020;37:168-182.e4 pubmed publisher
western blot; human; 1:1000; loading ...; fig 5a	Xu C, Zhang M, Bian L, Li Y, Yao Y, Li D. N-glycosylated SGK196 suppresses the metastasis of basal-like breast cancer cells. Oncogenesis. 2020;9:4 pubmed publisher
western blot; human; loading ...; fig 3i	Wang H, Chen Z, Wang S, Gao X, Qian M, Qiu W, et al. TGFβ1-induced beta-site APP-cleaving enzyme 2 upregulation promotes tumorigenesis through the NF-κB signalling pathway in human gliomas. Mol Oncol. 2020;14:407-425 pubmed publisher
western blot; human; loading ...; fig 5a	Chen X, Xiong X, Cui D, Yang F, Wei D, Li H, et al. DEPTOR is an in vivo tumor suppressor that inhibits prostate tumorigenesis via the inactivation of mTORC1/2 signals. Oncogene. 2020;39:1557-1571 pubmed publisher
immunoprecipitation; human; 1:50; loading ...; fig 5i	Yu S, Zhang Y, Li Q, Zhang Z, Zhao G, Xu J. CLDN6 promotes tumor progression through the YAP1-snail1 axis in gastric cancer. Cell Death Dis. 2019;10:949 pubmed publisher
western blot; mouse; 1:1000; loading ...; fig 4e	Wu Y, Chen K, Xing G, Li L, Ma B, Hu Z, et al. Phospholipid remodeling is critical for stem cell pluripotency by facilitating mesenchymal-to-epithelial transition. Sci Adv. 2019;5:eaax7525 pubmed publisher
western blot; human; loading ...; fig 6c	Li W, Zhang X, Wu F, Zhou Y, Bao Z, Li H, et al. Gastric cancer-derived mesenchymal stromal cells trigger M2 macrophage polarization that promotes metastasis and EMT in gastric cancer. Cell Death Dis. 2019;10:918 pubmed publisher
western blot; human; 1:1000; loading ...; fig 4f	Tan P, Xu Y, Du Y, Wu L, Guo B, Huang S, et al. SPOP suppresses pancreatic cancer progression by promoting the degradation of NANOG. Cell Death Dis. 2019;10:794 pubmed publisher
western blot; human; loading ...; fig 2a	Jiang S, Zhang M, Zhang Y, Zhou W, Zhu T, Ruan Q, et al. WNT5B governs the phenotype of basal-like breast cancer by activating WNT signaling. Cell Commun Signal. 2019;17:109 pubmed publisher
western blot; rat; 1:1000; fig 5a	Yin Y, Zhang Q, Zhao Q, Ding G, Wei C, Chang L, et al. Tongxinluo Attenuates Myocardiac Fibrosis after Acute Myocardial Infarction in Rats via Inhibition of Endothelial-to-Mesenchymal Transition. Biomed Res Int. 2019;2019:6595437 pubmed publisher
western blot; human; 1:2000; loading ...; fig 3c	Wang X, Liu R, Zhu W, Chu H, Yu H, Wei P, et al. UDP-glucose accelerates SNAI1 mRNA decay and impairs lung cancer metastasis. Nature. 2019;571:127-131 pubmed publisher
western blot; human; 1:1000; loading ...; fig s2a	Sonego M, Pellarin I, Costa A, Vinciguerra G, Coan M, Kraut A, et al. USP1 links platinum resistance to cancer cell dissemination by regulating Snail stability. Sci Adv. 2019;5:eaav3235 pubmed publisher
western blot; mouse; loading ...; fig 4e, 5f	Huang X, Xue H, Ma J, Zhang Y, Zhang J, Liu Y, et al. Salidroside ameliorates Adriamycin nephropathy in mice by inhibiting β-catenin activity. J Cell Mol Med. 2019;23:4443-4453 pubmed publisher
western blot; mouse; 1:1000; loading ...; fig 1d	Jung H, Fattet L, Tsai J, Kajimoto T, Chang Q, Newton A, et al. Apical-basal polarity inhibits epithelial-mesenchymal transition and tumour metastasis by PAR-complex-mediated SNAI1 degradation. Nat Cell Biol. 2019;21:359-371 pubmed publisher
immunohistochemistry - frozen section; mouse; 1:100; loading ...; fig 2a	Li Y, Hu Q, Li C, Liang K, Xiang Y, Hsiao H, et al. PTEN-induced partial epithelial-mesenchymal transition drives diabetic kidney disease. J Clin Invest. 2019;129:1129-1151 pubmed publisher
western blot; human; 1:1000; loading ...; fig 3a	Liu Z, Liu J, Dong X, Hu X, Jiang Y, Li L, et al. Tn antigen promotes human colorectal cancer metastasis via H-Ras mediated epithelial-mesenchymal transition activation. J Cell Mol Med. 2019;23:2083-2092 pubmed publisher
western blot; human; 1:500; loading ...; fig 2i	Aggarwal S, Gabrovsek L, Langeberg L, Golkowski M, Ong S, Smith F, et al. Depletion of dAKAP1-protein kinase A signaling islands from the outer mitochondrial membrane alters breast cancer cell metabolism and motility. J Biol Chem. 2019;294:3152-3168 pubmed publisher
western blot; human; loading ...; fig 7c, 7e	Zhang Z, Chen J, Huang W, Ning D, Liu Q, Wang C, et al. FAM134B induces tumorigenesis and epithelial-to-mesenchymal transition via Akt signaling in hepatocellular carcinoma. Mol Oncol. 2019;13:792-810 pubmed publisher
immunohistochemistry - frozen section; mouse; 1:50; loading ...; fig s3c	Pommier A, Anaparthy N, Memos N, Kelley Z, Gouronnec A, Yan R, et al. Unresolved endoplasmic reticulum stress engenders immune-resistant, latent pancreatic cancer metastases. Science. 2018;360: pubmed publisher
western blot; human; loading ...; fig 5c	Huang G, Jiang H, Lin Y, Wu Y, Cai W, Shi B, et al. lncAKHE enhances cell growth and migration in hepatocellular carcinoma via activation of NOTCH2 signaling. Cell Death Dis. 2018;9:487 pubmed publisher
western blot; human; 1:1000; loading ...; fig 2c	Wang J, Ye Q, Cao Y, Guo Y, Huang X, Mi W, et al. Snail determines the therapeutic response to mTOR kinase inhibitors by transcriptional repression of 4E-BP1. Nat Commun. 2017;8:2207 pubmed publisher
western blot; human; loading ...; fig 2e	Hiramoto H, Muramatsu T, Ichikawa D, Tanimoto K, Yasukawa S, Otsuji E, et al. miR-509-5p and miR-1243 increase the sensitivity to gemcitabine by inhibiting epithelial-mesenchymal transition in pancreatic cancer. Sci Rep. 2017;7:4002 pubmed publisher
western blot; human; loading ...; fig 4a	Yoon C, Cho S, Chang K, Park D, Ryeom S, Yoon S. Role of Rac1 Pathway in Epithelial-to-Mesenchymal Transition and Cancer Stem-like Cell Phenotypes in Gastric Adenocarcinoma. Mol Cancer Res. 2017;15:1106-1116 pubmed publisher
western blot; human; loading ...; fig 4c	Li P, Wang Y, Mao X, Jiang Y, Liu J, Li J, et al. CRB3 downregulation confers breast cancer stem cell traits through TAZ/?-catenin. Oncogenesis. 2017;6:e322 pubmed publisher
western blot; human; 1:1000; fig 1c	Kim D, Ko H, Park G, Hur D, Kim Y, Yang J. Vandetanib and ADAM inhibitors synergistically attenuate the pathological migration of EBV-infected retinal pigment epithelial cells by regulating the VEGF-mediated MAPK pathway. Exp Ther Med. 2017;13:1415-1425 pubmed publisher
western blot; human; 1:500; loading ...; fig 4C	Hu X, Zhang Z, Liang Z, Xie D, Zhang T, Yu D, et al. Downregulation of feline sarcoma-related protein inhibits cell migration, invasion and epithelial-mesenchymal transition via the ERK/AP-1 pathway in bladder urothelial cell carcinoma. Oncol Lett. 2017;13:686-694 pubmed publisher
western blot; human; loading ...; fig s2	Qiu X, Pascal L, Song Q, Zang Y, Ai J, O Malley K, et al. Physical and Functional Interactions between ELL2 and RB in the Suppression of Prostate Cancer Cell Proliferation, Migration, and Invasion. Neoplasia. 2017;19:207-215 pubmed publisher
immunohistochemistry; human; loading ...; fig 6b western blot; human; loading ...; fig 4c	Zhai S, Liu C, Zhang L, Zhu J, Guo J, Zhang J, et al. PLCE1 Promotes Esophageal Cancer Cell Progression by Maintaining the Transcriptional Activity of Snail. Neoplasia. 2017;19:154-164 pubmed publisher
western blot; human; loading ...; fig 5c	Xu J, Zhang X, Wang H, Ge S, Gao T, Song L, et al. HCRP1 downregulation promotes hepatocellular carcinoma cell migration and invasion through the induction of EGFR activation and epithelial-mesenchymal transition. Biomed Pharmacother. 2017;88:421-429 pubmed publisher
western blot; human; 1:1000; loading ...; fig 4d	Zangari J, Ilie M, Rouaud F, Signetti L, Ohanna M, Didier R, et al. Rapid decay of engulfed extracellular miRNA by XRN1 exonuclease promotes transient epithelial-mesenchymal transition. Nucleic Acids Res. 2017;45:4131-4141 pubmed publisher
western blot; human; fig 5a	Che D, Zhou T, Lan Y, Xie J, Gong H, Li C, et al. High glucose-induced epithelial-mesenchymal transition contributes to the upregulation of fibrogenic factors in retinal pigment epithelial cells. Int J Mol Med. 2016;38:1815-1822 pubmed publisher
western blot; human; 1:1000; loading ...; fig 7f	Zeng Y, Yao X, Chen L, Yan Z, Liu J, Zhang Y, et al. Sphingosine-1-phosphate induced epithelial-mesenchymal transition of hepatocellular carcinoma via an MMP-7/ syndecan-1/TGF-Î² autocrine loop. Oncotarget. 2016;7:63324-63337 pubmed publisher
western blot; human; 1:1000; fig 3	Jiang S, Gao Y, Hou W, Liu R, Qi X, Xu X, et al. Sinomenine inhibits A549 human lung cancer cell invasion by mediating the STAT3 signaling pathway. Oncol Lett. 2016;12:1380-1386 pubmed
western blot; human; loading ...; fig 6e	Im J, Yoon S, Kim B, Ban H, Won K, Chung K, et al. DNA damage induced apoptosis suppressor (DDIAS) is upregulated via ERK5/MEF2B signaling and promotes ?-catenin-mediated invasion. Biochim Biophys Acta. 2016;1859:1449-1458 pubmed publisher
western blot; human; 1:1000; loading ...; fig 3a	Yang S, Tsai C, Pan Y, Yeh C, Pang J, Takano M, et al. MART-10, a newly synthesized vitamin D analog, represses metastatic potential of head and neck squamous carcinoma cells. Drug Des Devel Ther. 2016;10:1995-2002 pubmed publisher
immunohistochemistry; mouse; loading ...; fig 8i	Zhang Q, Liu S, Parajuli K, Zhang W, Zhang K, Mo Z, et al. Interleukin-17 promotes prostate cancer via MMP7-induced epithelial-to-mesenchymal transition. Oncogene. 2017;36:687-699 pubmed publisher
western blot; human; 1:2000; loading ...; fig 5b	Chen H, Lorton B, Gupta V, Shechter D. A TGFβ-PRMT5-MEP50 axis regulates cancer cell invasion through histone H3 and H4 arginine methylation coupled transcriptional activation and repression. Oncogene. 2017;36:373-386 pubmed publisher
western blot; human; fig 2	Kuang J, Li L, Guo L, Su Y, Wang Y, Xu Y, et al. RNF8 promotes epithelial-mesenchymal transition of breast cancer cells. J Exp Clin Cancer Res. 2016;35:88 pubmed publisher
western blot; human; fig 6b	Chesnokova V, Zonis S, Zhou C, Recouvreux M, Ben Shlomo A, Araki T, et al. Growth hormone is permissive for neoplastic colon growth. Proc Natl Acad Sci U S A. 2016;113:E3250-9 pubmed publisher
western blot; human; 1:1000; fig s3b	Pattabiraman D, Bierie B, Kober K, Thiru P, Krall J, Zill C, et al. Activation of PKA leads to mesenchymal-to-epithelial transition and loss of tumor-initiating ability. Science. 2016;351:aad3680 pubmed publisher
western blot; human; loading ...; fig 4b	Matsuda Y, Miura K, Yamane J, Shima H, Fujibuchi W, Ishida K, et al. SERPINI1 regulates epithelial-mesenchymal transition in an orthotopic implantation model of colorectal cancer. Cancer Sci. 2016;107:619-28 pubmed publisher
western blot; human; fig 4	Kim D, Helfman D. Loss of MLCK leads to disruption of cell-cell adhesion and invasive behavior of breast epithelial cells via increased expression of EGFR and ERK/JNK signaling. Oncogene. 2016;35:4495-508 pubmed publisher
western blot; human; 1:1000; loading ...; fig 4h	Yan L, Liu Y, Xiang J, Wu Q, Xu L, Luo X, et al. PIK3R1 targeting by miR-21 suppresses tumor cell migration and invasion by reducing PI3K/AKT signaling and reversing EMT, and predicts clinical outcome of breast cancer. Int J Oncol. 2016;48:471-84 pubmed publisher
immunocytochemistry; human; fig 4 western blot; human; 1:1000; fig 2	Osorio L, FarfÃ¡n N, CastellÃ³n E, Contreras H. SNAIL transcription factor increases the motility and invasive capacity of prostate cancer cells. Mol Med Rep. 2016;13:778-86 pubmed publisher
western blot; human; 1:1000; fig 1b	Rafehi S, Ramos Valdes Y, Bertrand M, McGee J, PrÃ©fontaine M, Sugimoto A, et al. TGFβ signaling regulates epithelial-mesenchymal plasticity in ovarian cancer ascites-derived spheroids. Endocr Relat Cancer. 2016;23:147-59 pubmed publisher
western blot; human; 1:1000; loading ...; fig S5A	Pai P, Rachagani S, Lakshmanan I, Macha M, Sheinin Y, Smith L, et al. The canonical Wnt pathway regulates the metastasis-promoting mucin MUC4 in pancreatic ductal adenocarcinoma. Mol Oncol. 2016;10:224-39 pubmed publisher
western blot; human; fig 7a	Yokdang N, Hatakeyama J, Wald J, Simion C, Tellez J, Chang D, et al. LRIG1 opposes epithelial-to-mesenchymal transition and inhibits invasion of basal-like breast cancer cells. Oncogene. 2016;35:2932-47 pubmed publisher
western blot; human; 1:1000; loading ...; fig 3d	Kuang X, Zhu J, Peng Z, Wang J, Chen Z. Transducin (Beta)-Like 1 X-Linked Receptor 1 Correlates with Clinical Prognosis and Epithelial-Mesenchymal Transition in Hepatocellular Carcinoma. Dig Dis Sci. 2016;61:489-500 pubmed publisher
western blot; mouse; 1:1000; fig 1	Zhao Y, Londono P, Cao Y, Sharpe E, Proenza C, O Rourke R, et al. High-efficiency reprogramming of fibroblasts into cardiomyocytes requires suppression of pro-fibrotic signalling. Nat Commun. 2015;6:8243 pubmed publisher
western blot; human; fig 1	Zhang Y, Wei X, Liang Y, Chen W, Zhang F, Bai J, et al. Over-Expressed Twist Associates with Markers of Epithelial Mesenchymal Transition and Predicts Poor Prognosis in Breast Cancers via ERK and Akt Activation. PLoS ONE. 2015;10:e0135851 pubmed publisher
western blot; mouse; 1:1000; fig 6	Mehrabian M, Brethour D, Wang H, Xi Z, Rogaeva E, Schmitt Ulms G. The Prion Protein Controls Polysialylation of Neural Cell Adhesion Molecule 1 during Cellular Morphogenesis. PLoS ONE. 2015;10:e0133741 pubmed publisher
western blot; human	Picot N, Guerrette R, Beauregard A, Jean S, Michaud P, Harquail J, et al. Mammaglobin 1 promotes breast cancer malignancy and confers sensitivity to anticancer drugs. Mol Carcinog. 2016;55:1150-62 pubmed publisher
western blot; human; 1:1000; fig 4	Krishnan S, Szabo E, Burghardt I, Frei K, Tabatabai G, Weller M. Modulation of cerebral endothelial cell function by TGF-Î² in glioblastoma: VEGF-dependent angiogenesis versus endothelial mesenchymal transition. Oncotarget. 2015;6:22480-95 pubmed
western blot; human; fig 4	Kawamura N, Nimura K, Nagano H, Yamaguchi S, Nonomura N, Kaneda Y. CRISPR/Cas9-mediated gene knockout of NANOG and NANOGP8 decreases the malignant potential of prostate cancer cells. Oncotarget. 2015;6:22361-74 pubmed
western blot; human	Duvall Noelle N, Karwandyar A, Richmond A, Raman D. LASP-1: a nuclear hub for the UHRF1-DNMT1-G9a-Snail1 complex. Oncogene. 2016;35:1122-33 pubmed publisher
western blot; mouse; 1:1000; fig 6	Lin X, Xu W, Shao M, Fan Q, Wen G, Li C, et al. Shenling Baizhu San supresses colitis associated colorectal cancer through inhibition of epithelial-mesenchymal transition and myeloid-derived suppressor infiltration. BMC Complement Altern Med. 2015;15:126 pubmed publisher
western blot; human; fig s7	Min K, Liggett J, Silva G, Wu W, Wang R, Shen R, et al. NAG-1/GDF15 accumulates in the nucleus and modulates transcriptional regulation of the Smad pathway. Oncogene. 2016;35:377-88 pubmed publisher
western blot; human	Maity G, De A, Das A, Banerjee S, Sarkar S, Banerjee S. Aspirin blocks growth of breast tumor cells and tumor-initiating cells and induces reprogramming factors of mesenchymal to epithelial transition. Lab Invest. 2015;95:702-17 pubmed publisher
western blot; human; fig 3b	Li Y, Drabsch Y, Pujuguet P, Ren J, van Laar T, Zhang L, et al. Genetic depletion and pharmacological targeting of Î±v integrin in breast cancer cells impairs metastasis in zebrafish and mouse xenograft models. Breast Cancer Res. 2015;17:28 pubmed publisher
other; human; loading ...; fig 4c, 4f	Yamada A, Aki T, Unuma K, Funakoshi T, Uemura K. Paraquat induces epithelial-mesenchymal transition-like cellular response resulting in fibrogenesis and the prevention of apoptosis in human pulmonary epithelial cells. PLoS ONE. 2015;10:e0120192 pubmed publisher
immunocytochemistry; human; 1:100 western blot; human	Costabile V, Duraturo F, Delrio P, Rega D, Pace U, Liccardo R, et al. Lithium chloride induces mesenchymalâ€‘toâ€‘epithelial reverting transition in primary colon cancer cell cultures. Int J Oncol. 2015;46:1913-23 pubmed publisher
western blot; human; 1:1000; fig 4	Wang H, Bao W, Jiang F, Che Q, Chen Z, Wang F, et al. Mutant p53 (p53-R248Q) functions as an oncogene in promoting endometrial cancer by up-regulating REGÎ³. Cancer Lett. 2015;360:269-79 pubmed publisher
western blot; human; 1:500	Wei H, Nickoloff J, Chen W, Liu H, Lo W, Chang Y, et al. FOXF1 mediates mesenchymal stem cell fusion-induced reprogramming of lung cancer cells. Oncotarget. 2014;5:9514-29 pubmed
western blot; human	Lu G, Zhang Q, Huang Y, Song J, Tomaino R, Ehrenberger T, et al. Phosphorylation of ETS1 by Src family kinases prevents its recognition by the COP1 tumor suppressor. Cancer Cell. 2014;26:222-34 pubmed publisher
western blot; human; 1:1000; fig 1a	Zhang P, Wei Y, Wang L, Debeb B, Yuan Y, Zhang J, et al. ATM-mediated stabilization of ZEB1 promotes DNA damage response and radioresistance through CHK1. Nat Cell Biol. 2014;16:864-75 pubmed publisher
western blot; human	Subramani R, Lopez Valdez R, Arumugam A, Nandy S, Boopalan T, Lakshmanaswamy R. Targeting insulin-like growth factor 1 receptor inhibits pancreatic cancer growth and metastasis. PLoS ONE. 2014;9:e97016 pubmed publisher
immunocytochemistry; human western blot; human	Li A, Morton J, Ma Y, Karim S, Zhou Y, Faller W, et al. Fascin is regulated by slug, promotes progression of pancreatic cancer in mice, and is associated with patient outcomes. Gastroenterology. 2014;146:1386-96.e1-17 pubmed publisher
western blot; human	D Anselmi F, Masiello M, Cucina A, Proietti S, Dinicola S, Pasqualato A, et al. Microenvironment promotes tumor cell reprogramming in human breast cancer cell lines. PLoS ONE. 2013;8:e83770 pubmed publisher
western blot; human	Wu K, Chen K, Wang C, Jiao X, Wang L, Zhou J, et al. Cell fate factor DACH1 represses YB-1-mediated oncogenic transcription and translation. Cancer Res. 2014;74:829-39 pubmed publisher
immunohistochemistry - paraffin section; human; 1:100	Luo W, Yao K. Cancer stem cell characteristics, ALDH1 expression in the invasive front of nasopharyngeal carcinoma. Virchows Arch. 2014;464:35-43 pubmed publisher
western blot; human	Harazono Y, Muramatsu T, Endo H, Uzawa N, Kawano T, Harada K, et al. miR-655 Is an EMT-suppressive microRNA targeting ZEB1 and TGFBR2. PLoS ONE. 2013;8:e62757 pubmed publisher
ChIP-Seq; human western blot; human	Wu C, Tang S, Wang P, Lee H, Ko J. Nickel-induced epithelial-mesenchymal transition by reactive oxygen species generation and E-cadherin promoter hypermethylation. J Biol Chem. 2012;287:25292-302 pubmed publisher
	Hu J, Kong S, Dong T, Lin Z, Zhang Q, Chen X, et al. Autophagy modulates mesenchymal-to-endothelial transition via p53. Aging (Albany NY). 2020;12:22112-22121 pubmed publisher
	Seo H, Kim H, Yoon J, Kweon T, Park Y, Kang J, et al. Mutual regulation between OGT and XIAP to control colon cancer cell growth and invasion. Cell Death Dis. 2020;11:815 pubmed publisher
	Fahlbusch S, Keil S, Epplen J, Zanker K, Dittmar T. Comparison of hybrid clones derived from human breast epithelial cells and three different cancer cell lines regarding in vitro cancer stem/ initiating cell properties. BMC Cancer. 2020;20:446 pubmed publisher
	Gu Y, Wang W, Wang X, Xie H, Ye X, Shu P. Integrated network analysis identifies hsa-miR-4756-3p as a regulator of FOXM1 in Triple Negative Breast Cancer. Sci Rep. 2019;9:13830 pubmed publisher
	Zhang Y, Li T, Zhang L, Shangguan F, Shi G, Wu X, et al. Targeting the functional interplay between endoplasmic reticulum oxidoreductin-1α and protein disulfide isomerase suppresses the progression of cervical cancer. EBioMedicine. 2019;41:408-419 pubmed publisher
	Deng W, Fernandez A, McLaughlin S, Klinke D. WNT1-inducible signaling pathway protein 1 (WISP1/CCN4) stimulates melanoma invasion and metastasis by promoting the epithelial-mesenchymal transition. J Biol Chem. 2019;294:5261-5280 pubmed publisher
	Sanawar R, Mohan Dan V, Santhoshkumar T, Kumar R, Pillai M. Estrogen receptor-α regulation of microRNA-590 targets FAM171A1-a modifier of breast cancer invasiveness. Oncogenesis. 2019;8:5 pubmed publisher
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product information

SKU :

3879S

Product-Name :

Snail (C15D3) Rabbit mAb

Size :

100 ul

Price-(USD) :

235 USD

Species-x-Reactivity :

H, M, R, Mk

Applications :

Immunoprecipitation

Product-Category :

Developmental Biology

Shipping-Temp :

AMBIENT

Storage-Temp :

-20°C

Product-Type :

Monoclonal Antibody

MW :

Host :

Rabbit

Target :

Snail

Primary-Protein :

Snail1

Alt-Names :

Protein sna,Protein snail homolog 1,SLUGH2,SNA,SNAH,SNAI1,Zinc finger protein SNAI1,dJ710H13.1,snail 1 homolog,snail 1 zinc finger protein,snail 1, zinc finger protein,snail homolog 1 (Drosophila)

more info or order :

Cell Signaling Technology product webpage