| Published Application/Species/Dilution | Reference |
|---|
- western blot; human; 1:1000; tbl s6
| Mair B, Konopka T, Kerzendorfer C, Sleiman K, Salic S, Serra V, et al. Gain- and Loss-of-Function Mutations in the Breast Cancer Gene GATA3 Result in Differential Drug Sensitivity. PLoS Genet. 2016;12:e1006279 pubmed publisher |
- western blot; human; fig 2
| O'Hayre M, Inoue A, Kufareva I, Wang Z, Mikelis C, Drummond R, et al. Inactivating mutations in GNA13 and RHOA in Burkitt's lymphoma and diffuse large B-cell lymphoma: a tumor suppressor function for the Gα13/RhoA axis in B cells. Oncogene. 2016;35:3771-80 pubmed publisher |
| Fujimura K, Choi S, Wyse M, Strnadel J, Wright T, Klemke R. Eukaryotic Translation Initiation Factor 5A (EIF5A) Regulates Pancreatic Cancer Metastasis by Modulating RhoA and Rho-associated Kinase (ROCK) Protein Expression Levels. J Biol Chem. 2015;290:29907-19 pubmed publisher |
- immunocytochemistry; human; fig 3c
| Seashore-Ludlow B, Rees M, Cheah J, Cokol M, Price E, Coletti M, et al. Harnessing Connectivity in a Large-Scale Small-Molecule Sensitivity Dataset. Cancer Discov. 2015;5:1210-23 pubmed publisher |
- western blot; mouse; 1:2000; fig 5
| Iglesias-Bartolomé R, Torres D, Marone R, Feng X, Martin D, Simaan M, et al. Inactivation of a Gα(s)-PKA tumour suppressor pathway in skin stem cells initiates basal-cell carcinogenesis. Nat Cell Biol. 2015;17:793-803 pubmed publisher |
- western blot; mouse; 1:1000; fig 5
| Vogel S, Bodenstein R, Chen Q, Feil S, Feil R, Rheinlaender J, et al. Platelet-derived HMGB1 is a critical mediator of thrombosis. J Clin Invest. 2015;125:4638-54 pubmed publisher |
- western blot; human; fig 3
- western blot; mouse; fig 1
| Lee S, Litan A, Li Z, Graves B, Lindsey S, Barwe S, et al. Na,K-ATPase β1-subunit is a target of sonic hedgehog signaling and enhances medulloblastoma tumorigenicity. Mol Cancer. 2015;14:159 pubmed publisher |
- western blot; mouse; 1:10,000; fig s1
| Jiang Q, Paramasivam M, Aressy B, Wu J, Bellani M, Tong W, et al. MERIT40 cooperates with BRCA2 to resolve DNA interstrand cross-links. Genes Dev. 2015;29:1955-68 pubmed publisher |
- western blot; mouse; 1:2000; fig 3
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| Shin J, Nunomiya A, Kitajima Y, Dan T, Miyata T, Nagatomi R. Prolyl hydroxylase domain 2 deficiency promotes skeletal muscle fiber-type transition via a calcineurin/NFATc1-dependent pathway. Skelet Muscle. 2016;6:5 pubmed publisher |
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| Sánchez-Contreras M, Baker M, Finch N, Nicholson A, Wojtas A, Wszolek Z, et al. Genetic screening and functional characterization of PDGFRB mutations associated with basal ganglia calcification of unknown etiology. Hum Mutat. 2014;35:964-71 pubmed publisher |
| Kovacevic-Grujicic N, Mojsin M, Popovic J, Petrovic I, Topalovic V, Stevanovic M. Cyclic AMP response element binding (CREB) protein acts as a positive regulator of SOX3 gene expression in NT2/D1 cells. BMB Rep. 2014;47:197-202 pubmed |
| Hosono Y, Abe T, Higuchi M, Kajii K, Sakuraba S, Tada S, et al. Tipin functions in the protection against topoisomerase I inhibitor. J Biol Chem. 2014;289:11374-84 pubmed publisher |
| Akiyama T, Shiraishi T, Qin J, Konno H, Akiyama N, Shinzawa M, et al. Mitochondria-nucleus shuttling FK506-binding protein 51 interacts with TRAF proteins and facilitates the RIG-I-like receptor-mediated expression of type I IFN. PLoS ONE. 2014;9:e95992 pubmed publisher |
| Niedan S, Kauer M, Aryee D, Kofler R, Schwentner R, Meier A, et al. Suppression of FOXO1 is responsible for a growth regulatory repressive transcriptional sub-signature of EWS-FLI1 in Ewing sarcoma. Oncogene. 2014;33:3927-38 pubmed publisher |
| Kudo-Sakamoto Y, Akazawa H, Ito K, Takano J, Yano M, Yabumoto C, et al. Calpain-dependent cleavage of N-cadherin is involved in the progression of post-myocardial infarction remodeling. J Biol Chem. 2014;289:19408-19 pubmed publisher |
| Cheung H, Dunbar C, Mórotz G, Cheng W, Chan H, Miller C, et al. FE65 interacts with ADP-ribosylation factor 6 to promote neurite outgrowth. FASEB J. 2014;28:337-49 pubmed publisher |
| Liu Y, Liu X, Hao W, Decker Y, Schomburg R, Fülöp L, et al. IKKβ deficiency in myeloid cells ameliorates Alzheimer's disease-related symptoms and pathology. J Neurosci. 2014;34:12982-99 pubmed publisher |
| Shimizu K, Uematsu A, Imai Y, Sawasaki T. Pctaire1/Cdk16 promotes skeletal myogenesis by inducing myoblast migration and fusion. FEBS Lett. 2014;588:3030-7 pubmed publisher |
| Pinz S, Unser S, Brueggemann S, Besl E, Al-Rifai N, Petkes H, et al. The synthetic α-bromo-2',3,4,4'-tetramethoxychalcone (α-Br-TMC) inhibits the JAK/STAT signaling pathway. PLoS ONE. 2014;9:e90275 pubmed publisher |
| Matsumoto Y, Inden M, Tamura A, Hatano R, Tsukita S, Asano S. Ezrin mediates neuritogenesis via down-regulation of RhoA activity in cultured cortical neurons. PLoS ONE. 2014;9:e105435 pubmed publisher |
| Hagenbeek T, Wu X, Choy L, Sanchez-Irizarry C, Seshagiri S, Stinson J, et al. Murine Pten(-/-) T-ALL requires non-redundant PI3K/mTOR and DLL4/Notch1 signals for maintenance and γc/TCR signals for thymic exit. Cancer Lett. 2014;346:237-48 pubmed publisher |
| Ting C, Huang H, Huang T, Wu C, Chen J. The mechanisms by which pardaxin, a natural cationic antimicrobial peptide, targets the endoplasmic reticulum and induces c-FOS. Biomaterials. 2014;35:3627-40 pubmed publisher |
| Benasciutti E, Mariani E, Oliva L, Scolari M, Perilli E, Barras E, et al. MHC class II transactivator is an in vivo regulator of osteoclast differentiation and bone homeostasis co-opted from adaptive immunity. J Bone Miner Res. 2014;29:290-303 pubmed publisher |
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| Du L, Xie J, Cheng X, Li X, Kong F, Jiang X, et al. Activation of sirtuin 1 attenuates cerebral ventricular streptozotocin-induced tau hyperphosphorylation and cognitive injuries in rat hippocampi. Age (Dordr). 2014;36:613-23 pubmed publisher |
| Gray E, Petsalaki E, James D, Bagshaw R, Stacey M, Rocks O, et al. Src homology 2 domain containing protein 5 (SH2D5) binds the breakpoint cluster region protein, BCR, and regulates levels of Rac1-GTP. J Biol Chem. 2014;289:35397-408 pubmed publisher |
| Ðermadi Bebek D, Valo S, Pussila M, Reyhani N, Sarantaus L, Lalowski M, et al. Inherited cancer predisposition sensitizes colonic mucosa to address Western diet effects and putative cancer-predisposing changes on mouse proteome. J Nutr Biochem. 2014;25:1196-206 pubmed publisher |
| Saito M, Kato Y, Ito E, Fujimoto J, Ishikawa K, Doi A, et al. Expression screening of 17q12-21 amplicon reveals GRB7 as an ERBB2-dependent oncogene. FEBS Lett. 2012;586:1708-14 pubmed publisher |
| Zhu T, Dou Z, Qin B, Jin C, Wang X, Xu L, et al. Phosphorylation of microtubule-binding protein Hec1 by mitotic kinase Aurora B specifies spindle checkpoint kinase Mps1 signaling at the kinetochore. J Biol Chem. 2013;288:36149-59 pubmed publisher |
| Takasugi N, Sasaki T, Ebinuma I, Osawa S, Isshiki H, Takeo K, et al. FTY720/fingolimod, a sphingosine analogue, reduces amyloid-β production in neurons. PLoS ONE. 2013;8:e64050 pubmed publisher |
| Hirota J, Im H, Rahman M, Rumzhum N, Manetsch M, Pascoe C, et al. The nucleotide-binding domain and leucine-rich repeat protein-3 inflammasome is not activated in airway smooth muscle upon toll-like receptor-2 ligation. Am J Respir Cell Mol Biol. 2013;49:517-24 pubmed publisher |
| Gallo M, De Luca A, Lamura L, Normanno N. Zoledronic acid blocks the interaction between mesenchymal stem cells and breast cancer cells: implications for adjuvant therapy of breast cancer. Ann Oncol. 2012;23:597-604 pubmed publisher |
| Lucas C, Cordero-Nieves H, Erbe R, McAlees J, Bhatia S, Hodes R, et al. Prohibitins and the cytoplasmic domain of CD86 cooperate to mediate CD86 signaling in B lymphocytes. J Immunol. 2013;190:723-36 pubmed publisher |
| Takahashi A, Morita M, Yokoyama K, Suzuki T, Yamamoto T. Tob2 inhibits peroxisome proliferator-activated receptor γ2 expression by sequestering Smads and C/EBPα during adipocyte differentiation. Mol Cell Biol. 2012;32:5067-77 pubmed publisher |
| Ono M, Yamada K, Endo A, Avolio F, Lamond A. Analysis of human protein replacement stable cell lines established using snoMEN-PR vector. PLoS ONE. 2013;8:e62305 pubmed publisher |
| Wei C, Bhattaram V, Igwe J, Fleming E, Tirnauer J. The LKB1 tumor suppressor controls spindle orientation and localization of activated AMPK in mitotic epithelial cells. PLoS ONE. 2012;7:e41118 pubmed publisher |
| Jalili A, Mertz K, Romanov J, Wagner C, Kalthoff F, Stuetz A, et al. NVP-LDE225, a potent and selective SMOOTHENED antagonist reduces melanoma growth in vitro and in vivo. PLoS ONE. 2013;8:e69064 pubmed publisher |
| Bernasconi M, Ueda S, Krukowski P, Bornhauser B, Ladell K, Dorner M, et al. Early gene expression changes by Epstein-Barr virus infection of B-cells indicate CDKs and survivin as therapeutic targets for post-transplant lymphoproliferative diseases. Int J Cancer. 2013;133:2341-50 pubmed publisher |
| Landmann F, Foster J, Slatko B, Sullivan W. Efficient in vitro RNA interference and immunofluorescence-based phenotype analysis in a human parasitic nematode, Brugia malayi. Parasit Vectors. 2012;5:16 pubmed publisher |
| Shimizu K, Sawasaki T. Nek5, a novel substrate for caspase-3, promotes skeletal muscle differentiation by up-regulating caspase activity. FEBS Lett. 2013;587:2219-25 pubmed publisher |
| Ma G, Yasunaga J, Fan J, Yanagawa S, Matsuoka M. HTLV-1 bZIP factor dysregulates the Wnt pathways to support proliferation and migration of adult T-cell leukemia cells. Oncogene. 2013;32:4222-30 pubmed publisher |
| Liu S, Sawada T, Lee S, Yu W, Silverio G, Alapatt P, et al. Parkinson's disease-associated kinase PINK1 regulates Miro protein level and axonal transport of mitochondria. PLoS Genet. 2012;8:e1002537 pubmed publisher |
| Dolečková I, Rárová L, Gruz J, Vondrusová M, Strnad M, Krystof V. Antiproliferative and antiangiogenic effects of flavone eupatorin, an active constituent of chloroform extract of Orthosiphon stamineus leaves. Fitoterapia. 2012;83:1000-7 pubmed publisher |
| Li S, Leshchyns'ka I, Chernyshova Y, Schachner M, Sytnyk V. The neural cell adhesion molecule (NCAM) associates with and signals through p21-activated kinase 1 (Pak1). J Neurosci. 2013;33:790-803 pubmed publisher |
| Latorre V, Sevilla L, Sanchis A, Perez P. Selective ablation of glucocorticoid receptor in mouse keratinocytes increases susceptibility to skin tumorigenesis. J Invest Dermatol. 2013;133:2771-9 pubmed publisher |
| Manetsch M, Seidel P, Heintz U, Che W, Hughes J, Ge Q, et al. TLR2 ligand engagement upregulates airway smooth muscle TNFα-induced cytokine production. Am J Physiol Lung Cell Mol Physiol. 2012;302:L838-45 pubmed publisher |
| Consonni A, Cipolla L, Guidetti G, Canobbio I, Ciraolo E, Hirsch E, et al. Role and regulation of phosphatidylinositol 3-kinase β in platelet integrin α2β1 signaling. Blood. 2012;119:847-56 pubmed publisher |
| Aten T, Redmond M, Weaver S, Love C, Joy R, Lapp A, et al. Tyrosine phosphorylation of the orphan receptor ESDN/DCBLD2 serves as a scaffold for the signaling adaptor CrkL. FEBS Lett. 2013;587:2313-8 pubmed publisher |
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| Oderup C, Lajevic M, Butcher E. Canonical and noncanonical Wnt proteins program dendritic cell responses for tolerance. J Immunol. 2013;190:6126-34 pubmed publisher |
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| Sáez de Guinoa J, Barrio L, Carrasco Y. Vinculin arrests motile B cells by stabilizing integrin clustering at the immune synapse. J Immunol. 2013;191:2742-51 pubmed publisher |
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| Ben M'barek K, Pla P, Orvoen S, Benstaali C, Godin J, Gardier A, et al. Huntingtin mediates anxiety/depression-related behaviors and hippocampal neurogenesis. J Neurosci. 2013;33:8608-20 pubmed publisher |
| Ishibashi Y, Matsui T, Ojima A, Nishino Y, Nakashima S, Maeda S, et al. Glucagon-like peptide-1 inhibits angiotensin II-induced mesangial cell damage via protein kinase A. Microvasc Res. 2012;84:395-8 pubmed publisher |
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| Li X, Lv B, Xie J, Liu J, Zhou X, Wang J. AGEs induce Alzheimer-like tau pathology and memory deficit via RAGE-mediated GSK-3 activation. Neurobiol Aging. 2012;33:1400-10 pubmed publisher |
| Xu W, Allbritton N, Lawrence D. SRC kinase regulation in progressively invasive cancer. PLoS ONE. 2012;7:e48867 pubmed publisher |
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| Sugimoto J, ROMANI A, Valentin-Torres A, Luciano A, Ramirez Kitchen C, Funderburg N, et al. Magnesium decreases inflammatory cytokine production: a novel innate immunomodulatory mechanism. J Immunol. 2012;188:6338-46 pubmed publisher |
| Ai L, Skehan R, Saydi J, Lin T, Brown K. Ataxia-Telangiectasia, Mutated (ATM)/Nuclear Factor κ light chain enhancer of activated B cells (NFκB) signaling controls basal and DNA damage-induced transglutaminase 2 expression. J Biol Chem. 2012;287:18330-41 pubmed publisher |
| Katayama R, Aoyama A, Yamori T, Qi J, Oh-hara T, Song Y, et al. Cytotoxic activity of tivantinib (ARQ 197) is not due solely to c-MET inhibition. Cancer Res. 2013;73:3087-96 pubmed publisher |
| Bior B, Ballif B. Dab1 stabilizes its interaction with Cin85 by suppressing Cin85 phosphorylation at serine 587. FEBS Lett. 2013;587:60-6 pubmed publisher |
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| Kim K, Lee K, Rhee K. CEP90 is required for the assembly and centrosomal accumulation of centriolar satellites, which is essential for primary cilia formation. PLoS ONE. 2012;7:e48196 pubmed publisher |
| Manser C, Vagnoni A, Guillot F, Davies J, Miller C. Cdk5/p35 phosphorylates lemur tyrosine kinase-2 to regulate protein phosphatase-1C phosphorylation and activity. J Neurochem. 2012;121:343-8 pubmed publisher |
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| Lee J, Pearson J, Maser B, Ingham R. Cleavage of the JunB transcription factor by caspases generates a carboxyl-terminal fragment that inhibits activator protein-1 transcriptional activity. J Biol Chem. 2013;288:21482-95 pubmed publisher |
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| González-Gugel E, Villa-Morales M, Santos J, Bueno M, Malumbres M, Rodriguez-Pinilla S, et al. Down-regulation of specific miRNAs enhances the expression of the gene Smoothened and contributes to T-cell lymphoblastic lymphoma development. Carcinogenesis. 2013;34:902-8 pubmed publisher |
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| Manetsch M, Rahman M, Patel B, Ramsay E, Rumzhum N, Alkhouri H, et al. Long-acting β2-agonists increase fluticasone propionate-induced mitogen-activated protein kinase phosphatase 1 (MKP-1) in airway smooth muscle cells. PLoS ONE. 2013;8:e59635 pubmed publisher |
| Li X, Du L, Cheng X, Jiang X, Zhang Y, Lv B, et al. Glycation exacerbates the neuronal toxicity of β-amyloid. Cell Death Dis. 2013;4:e673 pubmed publisher |
| Lyons P, Sapio M, Fricker L. Zebrafish cytosolic carboxypeptidases 1 and 5 are essential for embryonic development. J Biol Chem. 2013;288:30454-62 pubmed publisher |
