product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
α-Tubulin (DM1A) Mouse mAb
catalog :
3873
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
DM1A
reactivity :
Dictyostelium discoideum, human, mouse, rat, zebrafish , cat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, other
citations: 154
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:1000; loading ...; fig 2b
Queiroz A, Dantas E, Ramsamooj S, Murthy A, Ahmed M, Zunica E, et al. Blocking ActRIIB and restoring appetite reverses cachexia and improves survival in mice with lung cancer. Nat Commun. 2022;13:4633 pubmed publisher
  • western blot; zebrafish ; loading ...; fig 2a
Łysyganicz P, Pooranachandran N, Liu X, Adamson K, Zielonka K, Elworthy S, et al. Loss of Deacetylation Enzymes Hdac6 and Sirt2 Promotes Acetylation of Cytoplasmic Tubulin, but Suppresses Axonemal Acetylation in Zebrafish Cilia. Front Cell Dev Biol. 2021;9:676214 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 1d
Ercolano G, Gomez Cadena A, Dumauthioz N, Vanoni G, Kreutzfeldt M, Wyss T, et al. PPARɣ drives IL-33-dependent ILC2 pro-tumoral functions. Nat Commun. 2021;12:2538 pubmed publisher
  • western blot; mouse; 1:5000; loading ...; fig s6f
Mu W, Li S, Xu J, Guo X, Wu H, Chen Z, et al. Hypothalamic Rax+ tanycytes contribute to tissue repair and tumorigenesis upon oncogene activation in mice. Nat Commun. 2021;12:2288 pubmed publisher
  • western blot; human; fig 3e
Choi S, Kim D, Ahn Y, Lee E, Park J. Suppression of Foxo3-Gatm by miR-132-3p Accelerates Cyst Formation by Up-Regulating ROS in Autosomal Dominant Polycystic Kidney Disease. Biomol Ther (Seoul). 2021;29:311-320 pubmed publisher
  • immunocytochemistry; human; 1:5000; loading ...; fig 3g
Lian B, Pei Y, Jiang Y, Xue M, Li D, Li X, et al. Truncated HDAC9 identified by integrated genome-wide screen as the key modulator for paclitaxel resistance in triple-negative breast cancer. Theranostics. 2020;10:11092-11109 pubmed publisher
  • immunocytochemistry; human; 1:2000; loading ...; fig 2d
Mehta S, Algie M, Al Jabry T, McKinney C, Kannan S, Verma C, et al. Critical Role for Cold Shock Protein YB-1 in Cytokinesis. Cancers (Basel). 2020;12: pubmed publisher
  • western blot; human; loading ...; fig 5d
Yin S, Song M, Zhao R, Liu X, Kang W, Lee J, et al. Xanthohumol Inhibits the Growth of Keratin 18-Overexpressed Esophageal Squamous Cell Carcinoma in vitro and in vivo. Front Cell Dev Biol. 2020;8:366 pubmed publisher
  • western blot; human; loading ...; fig 4b
Dmitrieva N, Walts A, Nguyen D, Grubb A, Zhang X, Wang X, et al. Impaired angiogenesis and extracellular matrix metabolism in autosomal-dominant hyper-IgE syndrome. J Clin Invest. 2020;130:4167-4181 pubmed publisher
  • western blot; human; loading ...
Garshott D, Sundaramoorthy E, Leonard M, Bennett E. Distinct regulatory ribosomal ubiquitylation events are reversible and hierarchically organized. elife. 2020;9: pubmed publisher
  • western blot; rat; 1:10,000; loading ...; fig 8b
Moreno Blas D, Gorostieta Salas E, Pommer Alba A, Muciño Hernández G, Gerónimo Olvera C, Maciel Barón L, et al. Cortical neurons develop a senescence-like phenotype promoted by dysfunctional autophagy. Aging (Albany NY). 2019;11:6175-6198 pubmed publisher
  • immunohistochemistry - frozen section; human; loading ...; fig 1j
  • immunohistochemistry - paraffin section; human; 1:8000; loading ...; fig s10a
Nam S, Gupta V, Lee H, Lee J, Wisdom K, Varma S, et al. Cell cycle progression in confining microenvironments is regulated by a growth-responsive TRPV4-PI3K/Akt-p27Kip1 signaling axis. Sci Adv. 2019;5:eaaw6171 pubmed publisher
  • western blot; human; loading ...; fig 5d
Choi J, Zhong X, McAlpine W, Liao T, Zhang D, Fang B, et al. LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling. Science. 2019;364: pubmed publisher
  • western blot; mouse; fig s1b
Knox T, Sahakian E, Banik D, Hadley M, Palmer E, Noonepalle S, et al. Selective HDAC6 inhibitors improve anti-PD-1 immune checkpoint blockade therapy by decreasing the anti-inflammatory phenotype of macrophages and down-regulation of immunosuppressive proteins in tumor cells. Sci Rep. 2019;9:6136 pubmed publisher
  • other; mouse; 1:1000; loading ...; fig e1d
Ranek M, Kokkonen Simon K, Chen A, Dunkerly Eyring B, Vera M, Oeing C, et al. PKG1-modified TSC2 regulates mTORC1 activity to counter adverse cardiac stress. Nature. 2019;566:264-269 pubmed publisher
  • western blot; Dictyostelium discoideum; loading ...; fig 3d
Nichols J, Paschke P, Peak Chew S, Williams T, Tweedy L, Skehel M, et al. The Atypical MAP Kinase ErkB Transmits Distinct Chemotactic Signals through a Core Signaling Module. Dev Cell. 2019;48:491-505.e9 pubmed publisher
  • western blot; human; loading ...; fig 1a
Unni A, Harbourne B, Oh M, Wild S, Ferrarone J, Lockwood W, et al. Hyperactivation of ERK by multiple mechanisms is toxic to RTK-RAS mutation-driven lung adenocarcinoma cells. elife. 2018;7: pubmed publisher
  • western blot; mouse; 1:2500; loading ...; fig 1a
Kaliszewski M, Kennedy A, Blaes S, Shaffer R, Knott A, Song W, et al. SOD1 Lysine 123 Acetylation in the Adult Central Nervous System. Front Cell Neurosci. 2016;10:287 pubmed publisher
  • western blot; human; fig 2
Hrgovic I, Doll M, Kleemann J, Wang X, Zoeller N, Pinter A, et al. The histone deacetylase inhibitor trichostatin a decreases lymphangiogenesis by inducing apoptosis and cell cycle arrest via p21-dependent pathways. BMC Cancer. 2016;16:763 pubmed
  • western blot; human; 1:1000; tbl s6
Mair B, Konopka T, Kerzendorfer C, Sleiman K, Salic S, Serra V, et al. Gain- and Loss-of-Function Mutations in the Breast Cancer Gene GATA3 Result in Differential Drug Sensitivity. PLoS Genet. 2016;12:e1006279 pubmed publisher
  • immunocytochemistry; rat; 1:200; loading ...; fig 2a
  • western blot; rat; 1:1000; loading ...; fig 2c
Robison P, Caporizzo M, Ahmadzadeh H, Bogush A, Chen C, Margulies K, et al. Detyrosinated microtubules buckle and bear load in contracting cardiomyocytes. Science. 2016;352:aaf0659 pubmed publisher
  • immunocytochemistry; human; 1:4000; fig 4
Adam M, Matt S, Christian S, Hess Stumpp H, Haegebarth A, Hofmann T, et al. SIAH ubiquitin ligases regulate breast cancer cell migration and invasion independent of the oxygen status. Cell Cycle. 2015;14:3734-47 pubmed publisher
  • western blot; human; fig 2
O Hayre M, Inoue A, Kufareva I, Wang Z, Mikelis C, Drummond R, et al. Inactivating mutations in GNA13 and RHOA in Burkitt's lymphoma and diffuse large B-cell lymphoma: a tumor suppressor function for the Gα13/RhoA axis in B cells. Oncogene. 2016;35:3771-80 pubmed publisher
  • western blot; mouse; 1:1000; fig 5
Vogel S, Bodenstein R, Chen Q, Feil S, Feil R, Rheinlaender J, et al. Platelet-derived HMGB1 is a critical mediator of thrombosis. J Clin Invest. 2015;125:4638-54 pubmed publisher
  • western blot; human
Fujimura K, Choi S, Wyse M, Strnadel J, Wright T, Klemke R. Eukaryotic Translation Initiation Factor 5A (EIF5A) Regulates Pancreatic Cancer Metastasis by Modulating RhoA and Rho-associated Kinase (ROCK) Protein Expression Levels. J Biol Chem. 2015;290:29907-19 pubmed publisher
  • immunocytochemistry; human; fig 3c
Seashore Ludlow B, Rees M, Cheah J, Cokol M, Price E, Coletti M, et al. Harnessing Connectivity in a Large-Scale Small-Molecule Sensitivity Dataset. Cancer Discov. 2015;5:1210-23 pubmed publisher
  • western blot; mouse; fig s1
Piroli G, Manuel A, Clapper A, Walla M, Baatz J, Palmiter R, et al. Succination is Increased on Select Proteins in the Brainstem of the NADH dehydrogenase (ubiquinone) Fe-S protein 4 (Ndufs4) Knockout Mouse, a Model of Leigh Syndrome. Mol Cell Proteomics. 2016;15:445-61 pubmed publisher
  • western blot; mouse; 1:10,000; fig s1
Jiang Q, Paramasivam M, Aressy B, Wu J, Bellani M, Tong W, et al. MERIT40 cooperates with BRCA2 to resolve DNA interstrand cross-links. Genes Dev. 2015;29:1955-68 pubmed publisher
  • western blot; mouse; fig 1
  • western blot; human; fig 3
Lee S, Litan A, Li Z, Graves B, Lindsey S, Barwe S, et al. Na,K-ATPase β1-subunit is a target of sonic hedgehog signaling and enhances medulloblastoma tumorigenicity. Mol Cancer. 2015;14:159 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 8b
Yan K, Li L, Wang X, Hong R, Zhang Y, Yang H, et al. The deubiquitinating enzyme complex BRISC is required for proper mitotic spindle assembly in mammalian cells. J Cell Biol. 2015;210:209-24 pubmed publisher
  • western blot; mouse; 1:1000; fig 2
Zeng X, Wang H, Bai F, Zhou X, Li S, Ren L, et al. Identification of matrine as a promising novel drug for hepatic steatosis and glucose intolerance with HSP72 as an upstream target. Br J Pharmacol. 2015;172:4303-18 pubmed publisher
  • western blot; mouse; 1:2000; fig 5
Iglesias Bartolomé R, Torres D, Marone R, Feng X, Martin D, Simaan M, et al. Inactivation of a Gα(s)-PKA tumour suppressor pathway in skin stem cells initiates basal-cell carcinogenesis. Nat Cell Biol. 2015;17:793-803 pubmed publisher
  • western blot; human; 1:1000; fig 6
Popp M, Maquat L. Attenuation of nonsense-mediated mRNA decay facilitates the response to chemotherapeutics. Nat Commun. 2015;6:6632 pubmed publisher
  • western blot; mouse; 1:1000
Areta J, Hawley J, Ye J, Chan M, Coffey V. Increasing leucine concentration stimulates mechanistic target of rapamycin signaling and cell growth in C2C12 skeletal muscle cells. Nutr Res. 2014;34:1000-7 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 5b
Peterson E, Menon V, Gatti L, Kipping R, Dewasinghe D, Perego P, et al. Nucleolar targeting by platinum: p53-independent apoptosis follows rRNA inhibition, cell-cycle arrest, and DNA compaction. Mol Pharm. 2015;12:287-97 pubmed publisher
  • western blot; mouse; 1:2000; fig 3
Pooya S, Liu X, Kumar V, Anderson J, Imai F, Zhang W, et al. The tumour suppressor LKB1 regulates myelination through mitochondrial metabolism. Nat Commun. 2014;5:4993 pubmed publisher
  • western blot; human
Jeong H, Lee S, Yum J, Yeo C, Lee K. Smurf2 regulates the degradation of YY1. Biochim Biophys Acta. 2014;1843:2005-11 pubmed publisher
  • western blot; human
  • western blot; mouse
Luo J, Hosoki K, Bacsi A, Radak Z, Hegde M, Sur S, et al. 8-Oxoguanine DNA glycosylase-1-mediated DNA repair is associated with Rho GTPase activation and α-smooth muscle actin polymerization. Free Radic Biol Med. 2014;73:430-8 pubmed publisher
  • western blot; mouse; 1:10,000
Morabito M, Berman D, Schneider R, Zhang Y, Leibel R, Small S. Hyperleucinemia causes hippocampal retromer deficiency linking diabetes to Alzheimer's disease. Neurobiol Dis. 2014;65:188-92 pubmed publisher
  • western blot; cat; 1:750
Maniscalco L, Millan Y, Iussich S, Denina M, Sánchez Cespedes R, Gattino F, et al. Activation of mammalian target of rapamycin (mTOR) in triple negative feline mammary carcinomas. BMC Vet Res. 2013;9:80 pubmed publisher
  • western blot; human
Areta J, Burke L, Ross M, Camera D, West D, Broad E, et al. Timing and distribution of protein ingestion during prolonged recovery from resistance exercise alters myofibrillar protein synthesis. J Physiol. 2013;591:2319-31 pubmed publisher
  • western blot; human
Ford C, Jary E, Ma S, Nixdorf S, Heinzelmann Schwarz V, Ward R. The Wnt gatekeeper SFRP4 modulates EMT, cell migration and downstream Wnt signalling in serous ovarian cancer cells. PLoS ONE. 2013;8:e54362 pubmed publisher
  • western blot; rat
Feng H, Kang C, Dickman J, Koenig R, Awoyinka I, Zhang Y, et al. Training-induced mitochondrial adaptation: role of peroxisome proliferator-activated receptor ? coactivator-1?, nuclear factor-?B and ?-blockade. Exp Physiol. 2013;98:784-95 pubmed publisher
Kendall G, Watson S, Xu L, LaVigne C, Murchison W, Rakheja D, et al. PAX3-FOXO1 transgenic zebrafish models identify HES3 as a mediator of rhabdomyosarcoma tumorigenesis. elife. 2018;7: pubmed publisher
Kedves A, Gleim S, Liang X, Bonal D, Sigoillot F, Harbinski F, et al. Recurrent ubiquitin B silencing in gynecological cancers establishes dependence on ubiquitin C. J Clin Invest. 2017;127:4554-4568 pubmed publisher
Moder M, Velimezi G, Owusu M, Mazouzi A, Wiedner M, Ferreira da Silva J, et al. Parallel genome-wide screens identify synthetic viable interactions between the BLM helicase complex and Fanconi anemia. Nat Commun. 2017;8:1238 pubmed publisher
Mai W, Gosa L, Daniëls V, Ta L, Tsang J, Higgins B, et al. Cytoplasmic p53 couples oncogene-driven glucose metabolism to apoptosis and is a therapeutic target in glioblastoma. Nat Med. 2017;23:1342-1351 pubmed publisher
Dite T, Ling N, Scott J, Hoque A, Galic S, Parker B, et al. The autophagy initiator ULK1 sensitizes AMPK to allosteric drugs. Nat Commun. 2017;8:571 pubmed publisher
Han J, Valdez J, Ho D, Lee C, Kim H, Wang X, et al. Nuclear factor-erythroid-2 related transcription factor-1 (Nrf1) is regulated by O-GlcNAc transferase. Free Radic Biol Med. 2017;110:196-205 pubmed publisher
Ortinski P, O Donovan B, Dong X, Kantor B. Integrase-Deficient Lentiviral Vector as an All-in-One Platform for Highly Efficient CRISPR/Cas9-Mediated Gene Editing. Mol Ther Methods Clin Dev. 2017;5:153-164 pubmed publisher
Guedouari H, Daigle T, Scorrano L, Hébert Chatelain E. Sirtuin 5 protects mitochondria from fragmentation and degradation during starvation. Biochim Biophys Acta Mol Cell Res. 2017;1864:169-176 pubmed publisher
Krishnan V, Stoppel D, Nong Y, Johnson M, Nadler M, Ozkaynak E, et al. Autism gene Ube3a and seizures impair sociability by repressing VTA Cbln1. Nature. 2017;543:507-512 pubmed publisher
Pirnie S, Osman A, Zhu Y, Carmichael G. An Ultraconserved Element (UCE) controls homeostatic splicing of ARGLU1 mRNA. Nucleic Acids Res. 2017;45:3473-3486 pubmed publisher
Quinn S, Graves S, Dains McGahee C, Friedman E, Hassan H, Witkowski P, et al. Adenylyl cyclase 3/adenylyl cyclase-associated protein 1 (CAP1) complex mediates the anti-migratory effect of forskolin in pancreatic cancer cells. Mol Carcinog. 2017;56:1344-1360 pubmed publisher
Rose J, Huang P, Camp N, Ye J, Leidal A, Goreshnik I, et al. A computationally engineered RAS rheostat reveals RAS-ERK signaling dynamics. Nat Chem Biol. 2017;13:119-126 pubmed publisher
Chung D, Frausto R, Chiu S, Lin B, Aldave A. Investigating the Molecular Basis of PPCD3: Characterization of ZEB1 Regulation of COL4A3 Expression. Invest Ophthalmol Vis Sci. 2016;57:4136-43 pubmed publisher
Meitinger F, Anzola J, Kaulich M, Richardson A, Stender J, Benner C, et al. 53BP1 and USP28 mediate p53 activation and G1 arrest after centrosome loss or extended mitotic duration. J Cell Biol. 2016;214:155-66 pubmed publisher
Shin J, Nunomiya A, Kitajima Y, Dan T, Miyata T, Nagatomi R. Prolyl hydroxylase domain 2 deficiency promotes skeletal muscle fiber-type transition via a calcineurin/NFATc1-dependent pathway. Skelet Muscle. 2016;6:5 pubmed publisher
Beckta J, Dever S, Gnawali N, Khalil A, Sule A, Golding S, et al. Mutation of the BRCA1 SQ-cluster results in aberrant mitosis, reduced homologous recombination, and a compensatory increase in non-homologous end joining. Oncotarget. 2015;6:27674-87 pubmed publisher
Nakakido M, Deng Z, Suzuki T, Dohmae N, Nakamura Y, Hamamoto R. Dysregulation of AKT Pathway by SMYD2-Mediated Lysine Methylation on PTEN. Neoplasia. 2015;17:367-73 pubmed publisher
Matsuno M, Horiuchi J, Yuasa Y, Ofusa K, Miyashita T, Masuda T, et al. Long-term memory formation in Drosophila requires training-dependent glial transcription. J Neurosci. 2015;35:5557-65 pubmed publisher
Ainsua Enrich E, Serrano Candelas E, Álvarez Errico D, Picado C, Sayós J, Rivera J, et al. The adaptor 3BP2 is required for KIT receptor expression and human mast cell survival. J Immunol. 2015;194:4309-18 pubmed publisher
Tavernier N, Noatynska A, Panbianco C, Martino L, Van Hove L, Schwager F, et al. Cdk1 phosphorylates SPAT-1/Bora to trigger PLK-1 activation and drive mitotic entry in C. elegans embryos. J Cell Biol. 2015;208:661-9 pubmed publisher
Zhou J, Fujiwara T, Ye S, Li X, Zhao H. Ubiquitin E3 Ligase LNX2 is Critical for Osteoclastogenesis In Vitro by Regulating M-CSF/RANKL Signaling and Notch2. Calcif Tissue Int. 2015;96:465-75 pubmed publisher
Ito T, Taniguchi H, Fukagai K, Okamuro S, Kobayashi A. Inhibitory mechanism of FAT4 gene expression in response to actin dynamics during Src-induced carcinogenesis. PLoS ONE. 2015;10:e0118336 pubmed publisher
Vilquin P, Donini C, Villedieu M, Grisard E, Corbo L, Bachelot T, et al. MicroRNA-125b upregulation confers aromatase inhibitor resistance and is a novel marker of poor prognosis in breast cancer. Breast Cancer Res. 2015;17:13 pubmed publisher
Boggs A, Vitolo M, Whipple R, Charpentier M, Goloubeva O, Ioffe O, et al. ?-Tubulin acetylation elevated in metastatic and basal-like breast cancer cells promotes microtentacle formation, adhesion, and invasive migration. Cancer Res. 2015;75:203-15 pubmed publisher
Shang X, Wang Q, Liu X, Yao X, Cao F, Wang Q, et al. Fluorocitrate induced the alterations of memory-related proteins and tau hyperphosphorylation in SD rats. Neurosci Lett. 2015;584:230-5 pubmed publisher
Nagao Kitamoto H, Setoguchi T, Kitamoto S, Nakamura S, Tsuru A, Nagata M, et al. Ribosomal protein S3 regulates GLI2-mediated osteosarcoma invasion. Cancer Lett. 2015;356:855-61 pubmed publisher
Mardilovich K, Gabrielsen M, McGarry L, Orange C, Patel R, Shanks E, et al. Elevated LIM kinase 1 in nonmetastatic prostate cancer reflects its role in facilitating androgen receptor nuclear translocation. Mol Cancer Ther. 2015;14:246-58 pubmed publisher
Gray E, Petsalaki E, James D, Bagshaw R, Stacey M, Rocks O, et al. Src homology 2 domain containing protein 5 (SH2D5) binds the breakpoint cluster region protein, BCR, and regulates levels of Rac1-GTP. J Biol Chem. 2014;289:35397-408 pubmed publisher
Aoyama A, Katayama R, Oh hara T, Sato S, Okuno Y, Fujita N. Tivantinib (ARQ 197) exhibits antitumor activity by directly interacting with tubulin and overcomes ABC transporter-mediated drug resistance. Mol Cancer Ther. 2014;13:2978-90 pubmed publisher
Liu Y, Liu X, Hao W, Decker Y, Schomburg R, Fülöp L, et al. IKKβ deficiency in myeloid cells ameliorates Alzheimer's disease-related symptoms and pathology. J Neurosci. 2014;34:12982-99 pubmed publisher
Handke B, Szabad J, Lidsky P, Hafen E, Lehner C. Towards long term cultivation of Drosophila wing imaginal discs in vitro. PLoS ONE. 2014;9:e107333 pubmed publisher
Đermadi D, Valo S, Pussila M, Reyhani N, Sarantaus L, Lalowski M, et al. Inherited cancer predisposition sensitizes colonic mucosa to address Western diet effects and putative cancer-predisposing changes on mouse proteome. J Nutr Biochem. 2014;25:1196-1206 pubmed publisher
Chan M, Gravel M, Bramoullé A, Bridon G, Avizonis D, Shore G, et al. Synergy between the NAMPT inhibitor GMX1777(8) and pemetrexed in non-small cell lung cancer cells is mediated by PARP activation and enhanced NAD consumption. Cancer Res. 2014;74:5948-54 pubmed publisher
Matsumoto Y, Inden M, Tamura A, Hatano R, Tsukita S, Asano S. Ezrin mediates neuritogenesis via down-regulation of RhoA activity in cultured cortical neurons. PLoS ONE. 2014;9:e105435 pubmed publisher
Nagao Kitamoto H, Nagata M, Nagano S, Kitamoto S, Ishidou Y, Yamamoto T, et al. GLI2 is a novel therapeutic target for metastasis of osteosarcoma. Int J Cancer. 2015;136:1276-84 pubmed publisher
Shimizu K, Uematsu A, Imai Y, Sawasaki T. Pctaire1/Cdk16 promotes skeletal myogenesis by inducing myoblast migration and fusion. FEBS Lett. 2014;588:3030-7 pubmed publisher
Kudo Sakamoto Y, Akazawa H, Ito K, Takano J, Yano M, Yabumoto C, et al. Calpain-dependent cleavage of N-cadherin is involved in the progression of post-myocardial infarction remodeling. J Biol Chem. 2014;289:19408-19 pubmed publisher
Aguilar H, Urruticoechea A, Halonen P, Kiyotani K, Mushiroda T, Barril X, et al. VAV3 mediates resistance to breast cancer endocrine therapy. Breast Cancer Res. 2014;16:R53 pubmed publisher
Arase M, Horiguchi K, Ehata S, Morikawa M, Tsutsumi S, Aburatani H, et al. Transforming growth factor-?-induced lncRNA-Smad7 inhibits apoptosis of mouse breast cancer JygMC(A) cells. Cancer Sci. 2014;105:974-82 pubmed publisher
Sánchez Contreras M, Baker M, Finch N, Nicholson A, Wojtas A, Wszolek Z, et al. Genetic screening and functional characterization of PDGFRB mutations associated with basal ganglia calcification of unknown etiology. Hum Mutat. 2014;35:964-71 pubmed publisher
Akiyama T, Shiraishi T, Qin J, Konno H, Akiyama N, Shinzawa M, et al. Mitochondria-nucleus shuttling FK506-binding protein 51 interacts with TRAF proteins and facilitates the RIG-I-like receptor-mediated expression of type I IFN. PLoS ONE. 2014;9:e95992 pubmed publisher
Sharifi H, Furuya A, Jellinger R, Nekorchuk M, de Noronha C. Cullin4A and cullin4B are interchangeable for HIV Vpr and Vpx action through the CRL4 ubiquitin ligase complex. J Virol. 2014;88:6944-58 pubmed publisher
Kondo S, Bottos A, Allegood J, Masson R, Maurer F, Genoud C, et al. Memo has a novel role in S1P signaling and is [corrected] crucial for vascular development. PLoS ONE. 2014;9:e94114 pubmed publisher
Thorburn J, Andrysik Z, Staskiewicz L, Gump J, Maycotte P, Oberst A, et al. Autophagy controls the kinetics and extent of mitochondrial apoptosis by regulating PUMA levels. Cell Rep. 2014;7:45-52 pubmed publisher
Pinz S, Unser S, Brueggemann S, Besl E, Al Rifai N, Petkes H, et al. The synthetic ?-bromo-2',3,4,4'-tetramethoxychalcone (?-Br-TMC) inhibits the JAK/STAT signaling pathway. PLoS ONE. 2014;9:e90275 pubmed publisher
Hosono Y, Abe T, Higuchi M, Kajii K, Sakuraba S, Tada S, et al. Tipin functions in the protection against topoisomerase I inhibitor. J Biol Chem. 2014;289:11374-84 pubmed publisher
Almenar Queralt A, Falzone T, Shen Z, Lillo C, Killian R, Arreola A, et al. UV irradiation accelerates amyloid precursor protein (APP) processing and disrupts APP axonal transport. J Neurosci. 2014;34:3320-39 pubmed publisher
Okita N, Ishikawa N, Mizunoe Y, Oku M, Nagai W, Suzuki Y, et al. Inhibitory effect of p53 on mitochondrial content and function during adipogenesis. Biochem Biophys Res Commun. 2014;446:91-7 pubmed publisher
Ting C, Huang H, Huang T, Wu C, Chen J. The mechanisms by which pardaxin, a natural cationic antimicrobial peptide, targets the endoplasmic reticulum and induces c-FOS. Biomaterials. 2014;35:3627-40 pubmed publisher
Hagenbeek T, Wu X, Choy L, Sanchez Irizarry C, Seshagiri S, Stinson J, et al. Murine Pten(-/-) T-ALL requires non-redundant PI3K/mTOR and DLL4/Notch1 signals for maintenance and ?c/TCR signals for thymic exit. Cancer Lett. 2014;346:237-48 pubmed publisher
Galvão J, Davis B, Tilley M, Normando E, Duchen M, Cordeiro M. Unexpected low-dose toxicity of the universal solvent DMSO. FASEB J. 2014;28:1317-30 pubmed publisher
Kovacevic Grujicic N, Mojsin M, Popovic J, Petrovic I, Topalovic V, Stevanovic M. Cyclic AMP response element binding (CREB) protein acts as a positive regulator of SOX3 gene expression in NT2/D1 cells. BMB Rep. 2014;47:197-202 pubmed
El Mesery M, Trebing J, Schafer V, Weisenberger D, Siegmund D, Wajant H. CD40-directed scFv-TRAIL fusion proteins induce CD40-restricted tumor cell death and activate dendritic cells. Cell Death Dis. 2013;4:e916 pubmed publisher
Miyagawa K, Kondo T, Goto R, Matsuyama R, Ono K, Kitano S, et al. Effects of combination therapy with vildagliptin and valsartan in a mouse model of type 2 diabetes. Cardiovasc Diabetol. 2013;12:160 pubmed publisher
Zhu T, Dou Z, Qin B, Jin C, Wang X, Xu L, et al. Phosphorylation of microtubule-binding protein Hec1 by mitotic kinase Aurora B specifies spindle checkpoint kinase Mps1 signaling at the kinetochore. J Biol Chem. 2013;288:36149-59 pubmed publisher
Grivas P, Day K, Karatsinides A, Paul A, Shakir N, Owainati I, et al. Evaluation of the antitumor activity of dacomitinib in models of human bladder cancer. Mol Med. 2013;19:367-76 pubmed publisher
Du L, Xie J, Cheng X, Li X, Kong F, Jiang X, et al. Activation of sirtuin 1 attenuates cerebral ventricular streptozotocin-induced tau hyperphosphorylation and cognitive injuries in rat hippocampi. Age (Dordr). 2014;36:613-23 pubmed publisher
Cheung H, Dunbar C, Mórotz G, Cheng W, Chan H, Miller C, et al. FE65 interacts with ADP-ribosylation factor 6 to promote neurite outgrowth. FASEB J. 2014;28:337-49 pubmed publisher
Benasciutti E, Mariani E, Oliva L, Scolari M, Perilli E, Barras E, et al. MHC class II transactivator is an in vivo regulator of osteoclast differentiation and bone homeostasis co-opted from adaptive immunity. J Bone Miner Res. 2014;29:290-303 pubmed publisher
Lyons P, Sapio M, Fricker L. Zebrafish cytosolic carboxypeptidases 1 and 5 are essential for embryonic development. J Biol Chem. 2013;288:30454-62 pubmed publisher
Seidl M, Nunes F, Fels B, Hildebrandt I, Schmitz W, Schulze Osthoff K, et al. A novel intronic promoter of the Crem gene induces small ICER (smICER) isoforms. FASEB J. 2014;28:143-52 pubmed publisher
Niedan S, Kauer M, Aryee D, Kofler R, Schwentner R, Meier A, et al. Suppression of FOXO1 is responsible for a growth regulatory repressive transcriptional sub-signature of EWS-FLI1 in Ewing sarcoma. Oncogene. 2014;33:3927-38 pubmed publisher
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product information
SKU :
3873S
Product-Name :
α-Tubulin (DM1A) Mouse mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Immunofluorescence (Immunocytochemistry)
Product-Category :
Cytoskeletal Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
52
Host :
Mouse
Target :
tubulin alpha
Primary-Protein :
TUBA1B
Alt-Names :
Alpha-tubulin ubiquitous,K-ALPHA-1,TBA1B,TUBA1B,Tubulin K-alpha-1,Tubulin alpha-1B chain,Tubulin alpha-ubiquitous chain,alpha tubulin,tubulin, alpha 1b,tubulin, alpha, ubiquitous
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.