| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot knockout validation; human; fig 2a
| Botto S, Abraham J, Mizuno N, Pryke K, Gall B, Landais I, et al. Human Cytomegalovirus Immediate Early 86-kDa Protein Blocks Transcription and Induces Degradation of the Immature Interleukin-1β Protein during Virion-Mediated Activation of the AIM2 Inflammasome. MBio. 2019;10: pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 4g
| Jin X, Morro B, Tørresen O, Moiche V, Solbakken M, Jakobsen K, et al. Innovation in Nucleotide-Binding Oligomerization-Like Receptor and Toll-Like Receptor Sensing Drives the Major Histocompatibility Complex-II Free Atlantic Cod Immune System. Front Immunol. 2020;11:609456 pubmed publisher |
- western blot; mouse; loading ...; fig 3a
| Zhang X, Wang R, Hu D, Sun X, Fujioka H, Lundberg K, et al. Oligodendroglial glycolytic stress triggers inflammasome activation and neuropathology in Alzheimer's disease. Sci Adv. 2020;6: pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 1b
| Cai S, Ge M, Mennone A, Hoque R, Ouyang X, Boyer J. Inflammasome Is Activated in the Liver of Cholestatic Patients and Aggravates Hepatic Injury in Bile Duct-Ligated Mouse. Cell Mol Gastroenterol Hepatol. 2020;9:679-688 pubmed publisher |
- western blot; human; loading ...; fig 2j
| Managò A, Audrito V, Mazzola F, Sorci L, Gaudino F, Gizzi K, et al. Extracellular nicotinate phosphoribosyltransferase binds Toll like receptor 4 and mediates inflammation. Nat Commun. 2019;10:4116 pubmed publisher |
- western blot; human; loading ...; fig 2a, 3b
| Lin L, Xu L, Lv W, Han L, Xiang Y, Fu L, et al. An NLRP3 inflammasome-triggered cytokine storm contributes to Streptococcal toxic shock-like syndrome (STSLS). PLoS Pathog. 2019;15:e1007795 pubmed publisher |
- western blot; human; 1:1000; fig 1
| Lagrange B, Benaoudia S, Wallet P, Magnotti F, Provost A, Michal F, et al. Human caspase-4 detects tetra-acylated LPS and cytosolic Francisella and functions differently from murine caspase-11. Nat Commun. 2018;9:242 pubmed publisher |
- western blot; human; 1:1000; fig 3c
| Wang Y, Yin B, Li D, Wang G, Han X, Sun X. GSDME mediates caspase-3-dependent pyroptosis in gastric cancer. Biochem Biophys Res Commun. 2018;495:1418-1425 pubmed publisher |
- western blot; human; loading ...; fig 7h
| Tsugita M, Morimoto N, Tashiro M, Kinoshita K, Nakayama M. SR-B1 Is a Silica Receptor that Mediates Canonical Inflammasome Activation. Cell Rep. 2017;18:1298-1311 pubmed publisher |
- western blot; human; 1:200; loading ...; fig 5a
| Wang L, Cano M, Datta S, Wei H, Ebrahimi K, Gorashi Y, et al. Pentraxin 3 recruits complement factor H to protect against oxidative stress-induced complement and inflammasome overactivation. J Pathol. 2016;240:495-506 pubmed publisher |
- western blot; human; loading ...; fig 3c
| Wei Q, Guo P, Mu K, Zhang Y, Zhao W, Huai W, et al. Estrogen suppresses hepatocellular carcinoma cells through ERβ-mediated upregulation of the NLRP3 inflammasome. Lab Invest. 2015;95:804-16 pubmed publisher |
| Weng L, Mitoma H, Trichot C, Tricot C, Bao M, Liu Y, et al. The E3 ubiquitin ligase tripartite motif 33 is essential for cytosolic RNA-induced NLRP3 inflammasome activation. J Immunol. 2014;193:3676-82 pubmed publisher |
| Yang Q, Yu C, Yang Z, Wei Q, Mu K, Zhang Y, et al. Deregulated NLRP3 and NLRP1 inflammasomes and their correlations with disease activity in systemic lupus erythematosus. J Rheumatol. 2014;41:444-52 pubmed publisher |
| Kim N, Kim D, Song Y. SARS-CoV-2 Nonstructural Proteins 1 and 13 Suppress Caspase-1 and the NLRP3 Inflammasome Activation. Microorganisms. 2021;9: pubmed publisher |
| Goddard P, Sanchez Garrido J, Slater S, Kalyan M, Ruano Gallego D, Marches O, et al. Enteropathogenic Escherichia coli Stimulates Effector-Driven Rapid Caspase-4 Activation in Human Macrophages. Cell Rep. 2019;27:1008-1017.e6 pubmed publisher |
| Ryzhakov G, West N, Franchini F, Clare S, Ilott N, Sansom S, et al. Alpha kinase 1 controls intestinal inflammation by suppressing the IL-12/Th1 axis. Nat Commun. 2018;9:3797 pubmed publisher |
| Sharma M, Braun R. Cyclical expression of GDNF is required for spermatogonial stem cell homeostasis. Development. 2018;145: pubmed publisher |
| Jiao X, Velasco Velázquez M, Wang M, Li Z, Rui H, Peck A, et al. CCR5 Governs DNA Damage Repair and Breast Cancer Stem Cell Expansion. Cancer Res. 2018;78:1657-1671 pubmed publisher |
| Camilli G, Eren E, Williams D, Aimanianda V, Meunier E, Quintin J. Impaired phagocytosis directs human monocyte activation in response to fungal derived β-glucan particles. Eur J Immunol. 2018;48:757-770 pubmed publisher |
| Jeffery E, Church C, Holtrup B, Colman L, Rodeheffer M. Rapid depot-specific activation of adipocyte precursor cells at the onset of obesity. Nat Cell Biol. 2015;17:376-85 pubmed publisher |
