product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
APPL1 (D83H4) XP® Rabbit mAb
catalog :
3858
clonality :
monoclonal
host :
rabbit
conjugate :
nonconjugated
clone name :
D83H4
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation
citations: 9
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:1000; loading ...; fig ex1m
Rapino F, Delaunay S, Rambow F, Zhou Z, Tharun L, de Tullio P, et al. Codon-specific translation reprogramming promotes resistance to targeted therapy. Nature. 2018;558:605-609 pubmed publisher
  • western blot; human; 1:1000; fig 4a
Jung Y, Lee J, Sohn K, Lee Y, Seo Y, Kim C, et al. Adiponectin Signaling Regulates Lipid Production in Human Sebocytes. PLoS ONE. 2017;12:e0169824 pubmed publisher
  • immunohistochemistry; rat; fig 2a
Fernandez Monreal M, Sánchez Castillo C, Esteban J. APPL1 gates long-term potentiation through its plekstrin homology domain. J Cell Sci. 2016;129:2793-803 pubmed publisher
  • immunocytochemistry; human; fig 1
  • western blot; human; fig 2
Reis C, Chen P, Srinivasan S, Aguet F, Mettlen M, Schmid S. Crosstalk between Akt/GSK3β signaling and dynamin-1 regulates clathrin-mediated endocytosis. EMBO J. 2015;34:2132-46 pubmed publisher
  • western blot; mouse; 1:1000; fig s6
Braccini L, Ciraolo E, Campa C, Perino A, Longo D, Tibolla G, et al. PI3K-C2γ is a Rab5 effector selectively controlling endosomal Akt2 activation downstream of insulin signalling. Nat Commun. 2015;6:7400 pubmed publisher
  • immunocytochemistry; human; 10 ug/ml; fig s7
Phillips Krawczak C, Singla A, Starokadomskyy P, Deng Z, Osborne D, Li H, et al. COMMD1 is linked to the WASH complex and regulates endosomal trafficking of the copper transporter ATP7A. Mol Biol Cell. 2015;26:91-103 pubmed publisher
  • western blot; rat
Gulli R, Tishinsky J, Macdonald T, Robinson L, Wright D, Dyck D. Exercise restores insulin, but not adiponectin, response in skeletal muscle of high-fat fed rodents. Am J Physiol Regul Integr Comp Physiol. 2012;303:R1062-70 pubmed publisher
Sneeggen M, Pedersen N, Campsteijn C, Haugsten E, Stenmark H, Schink K. WDFY2 restrains matrix metalloproteinase secretion and cell invasion by controlling VAMP3-dependent recycling. Nat Commun. 2019;10:2850 pubmed publisher
Wang N, Li Z, Zhao H, Tao Y, Xu L, Lu J, et al. Molecular targeting of the oncoprotein PLK1 in pediatric acute myeloid leukemia: RO3280, a novel PLK1 inhibitor, induces apoptosis in leukemia cells. Int J Mol Sci. 2015;16:1266-92 pubmed publisher
product information
SKU :
3858S
Product-Name :
APPL1 (D83H4) XP® Rabbit mAb
Size :
100 ul
Price-(USD) :
260 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Immunofluorescence (Immunocytochemistry)
Product-Category :
Protein Folding and Trafficking
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
82
Host :
Rabbit
Target :
APPL1
Primary-Protein :
APPL
Alt-Names :
AKT2 interactor,APPL,APPL1,Adapter protein containing PH domain, PTB domain and leucine zipper motif 1,DCC-interacting protein 13-alpha,DIP13A,DIP13alpha,DP13A,Dip13-alpha,KIAA1428,adaptor protein containing pH domain, PTB domain and leucine zipper motif 1,adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1,signaling adaptor protein DIP13alpha
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.