product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
LIMK1 Antibody
catalog :
3842
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunoprecipitation, proximity ligation assay
citations: 15
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:100; loading ...; fig 9a
Vaswani A, Weykopf B, Hagemann C, Fried H, Brüstle O, Blaess S. Correct setup of the substantia nigra requires Reelin-mediated fast, laterally-directed migration of dopaminergic neurons. elife. 2019;8: pubmed publisher
  • proximity ligation assay; rat; 1:100; loading ...; fig 6d
  • western blot; rat; 1:1000; loading ...; fig 6a
Rajgor D, Sanderson T, Amici M, Collingridge G, Hanley J. NMDAR-dependent Argonaute 2 phosphorylation regulates miRNA activity and dendritic spine plasticity. EMBO J. 2018;37: pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 6a
Xiao Y, Ma H, Wan P, Qin D, Wang X, Zhang X, et al. Trp-Asp (WD) Repeat Domain 1 Is Essential for Mouse Peri-implantation Development and Regulates Cofilin Phosphorylation. J Biol Chem. 2017;292:1438-1448 pubmed publisher
  • western blot; rat; 1:1000; fig 3
Lauterborn J, Kramar E, Rice J, Babayan A, Cox C, Karsten C, et al. Cofilin Activation Is Temporally Associated with the Cessation of Growth in the Developing Hippocampus. Cereb Cortex. 2017;27:2640-2651 pubmed publisher
  • western blot; human; 1:200; fig st1
Treindl F, Ruprecht B, Beiter Y, Schultz S, Döttinger A, Staebler A, et al. A bead-based western for high-throughput cellular signal transduction analyses. Nat Commun. 2016;7:12852 pubmed publisher
  • western blot; rat; 1:1000
Briz V, Zhu G, Wang Y, Liu Y, Avetisyan M, Bi X, et al. Activity-dependent rapid local RhoA synthesis is required for hippocampal synaptic plasticity. J Neurosci. 2015;35:2269-82 pubmed publisher
  • western blot; human; 1:2000; fig s1
Li G, Zhou J, Budhraja A, Hu X, Chen Y, Cheng Q, et al. Mitochondrial translocation and interaction of cofilin and Drp1 are required for erucin-induced mitochondrial fission and apoptosis. Oncotarget. 2015;6:1834-49 pubmed
  • western blot; human; fig 5
D Hulst G, Sylow L, Hespel P, Deldicque L. Acute systemic insulin intolerance does not alter the response of the Akt/GSK-3 pathway to environmental hypoxia in human skeletal muscle. Eur J Appl Physiol. 2015;115:1219-31 pubmed publisher
  • western blot; human; 1:1000
Shi L, Zhang B, Sun X, Lu S, Liu Z, Liu Y, et al. MiR-204 inhibits human NSCLC metastasis through suppression of NUAK1. Br J Cancer. 2014;111:2316-27 pubmed publisher
  • immunohistochemistry; human; fig 1
  • western blot; human; fig 3
Mardilovich K, Gabrielsen M, McGarry L, Orange C, Patel R, Shanks E, et al. Elevated LIM kinase 1 in nonmetastatic prostate cancer reflects its role in facilitating androgen receptor nuclear translocation. Mol Cancer Ther. 2015;14:246-58 pubmed publisher
Tada H, Miyazaki T, Takemoto K, Takase K, Jitsuki S, Nakajima W, et al. Neonatal isolation augments social dominance by altering actin dynamics in the medial prefrontal cortex. Proc Natl Acad Sci U S A. 2016;113:E7097-E7105 pubmed publisher
Kempf S, Casciati A, Buratovic S, Janik D, von Toerne C, Ueffing M, et al. The cognitive defects of neonatally irradiated mice are accompanied by changed synaptic plasticity, adult neurogenesis and neuroinflammation. Mol Neurodegener. 2014;9:57 pubmed publisher
Shiobara T, Usui T, Han J, Isoda H, Nagumo Y. The reversible increase in tight junction permeability induced by capsaicin is mediated via cofilin-actin cytoskeletal dynamics and decreased level of occludin. PLoS ONE. 2013;8:e79954 pubmed publisher
Wu N, Sulpice E, Obeïd P, Benzina S, Kermarrec F, Combe S, et al. The miR-17 family links p63 protein to MAPK signaling to promote the onset of human keratinocyte differentiation. PLoS ONE. 2012;7:e45761 pubmed publisher
Park J, Arakawa Takeuchi S, Jinno S, Okayama H. Rho-associated kinase connects a cell cycle-controlling anchorage signal to the mammalian target of rapamycin pathway. J Biol Chem. 2011;286:23132-41 pubmed publisher
product information
SKU :
3842S
Product-Name :
LIMK1 Antibody
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Immunoprecipitation
Product-Category :
Cytoskeletal Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
70
Host :
Rabbit
Target :
LIMK1
Primary-Protein :
LIMK1
Alt-Names :
LIM domain kinase 1,LIM motif-containing protein kinase,LIMK,LIMK-1,LIMK1
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.