product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-PKM2 (Tyr105) Antibody
catalog :
3827
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
antigen modification :
phosphorylated
reactivity :
human, mouse, rat
application :
western blot, immunoprecipitation
citations: 4
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:1000; loading ...; fig 6a
Santacatterina F, Sánchez Aragó M, Catalán García M, Garrabou G, de Arenas C, Grau J, et al. Pyruvate kinase M2 and the mitochondrial ATPase Inhibitory Factor 1 provide novel biomarkers of dermatomyositis: a metabolic link to oncogenesis. J Transl Med. 2017;15:29 pubmed publisher
  • immunoprecipitation; human; fig 8
  • western blot; human; 1:1000; fig 7a
Iansante V, Choy P, Fung S, Liu Y, Chai J, Dyson J, et al. PARP14 promotes the Warburg effect in hepatocellular carcinoma by inhibiting JNK1-dependent PKM2 phosphorylation and activation. Nat Commun. 2015;6:7882 pubmed publisher
de Wit R, Mujić Delić A, van Senten J, Fraile Ramos A, Siderius M, Smit M. Human cytomegalovirus encoded chemokine receptor US28 activates the HIF-1α/PKM2 axis in glioblastoma cells. Oncotarget. 2016;7:67966-67985 pubmed publisher
Son S, Kim S, Moon E, Kim D, Pyo S, Um S. Prognostic significance and function of the vacuolar H+-ATPase subunit V1E1 in esophageal squamous cell carcinoma. Oncotarget. 2016;7:49334-49348 pubmed publisher
product information
SKU :
3827S
Product-Name :
Phospho-PKM2 (Tyr105) Antibody
Size :
100 ul
Price-(USD) :
274 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Western blot
Product-Category :
Metabolism
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
60
Host :
Rabbit
Target :
PKM2 (Tyr105) phosphate
Primary-Protein :
PKM2
Alt-Names :
CTHBP,Cytosolic thyroid hormone-binding protein,KPYM,MGC3932,OIP-3,OIP3,Opa-interacting protein 3,PK, muscle type,PK2,PK3,PKM,PKM2,Pyruvate kinase 2/3,Pyruvate kinase isozymes M1/M2,Pyruvate kinase muscle isozyme,TCB,THBP1,Thyroid hormone-binding protein 1,Tumor M2-PK,p58,pyruvate kinase, muscle,thyroid hormone-binding protein, cytosolic
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.