Bak Antibody | Cell Signaling Technology 3814 product information

product summary

company name :

Cell Signaling Technology

product type :

antibody

product name :

Bak Antibody

catalog :

3814

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot

more info or order :

Cell Signaling Technology product webpage

citations: 11

Published Application/Species/Sample/Dilution	Reference
western blot; human; 1:1000; loading ...; fig 3g	Zheleznyak A, Mixdorf M, Marsala L, Prior J, Yang X, Cui G, et al. Orthogonal targeting of osteoclasts and myeloma cells for radionuclide stimulated dynamic therapy induces multidimensional cell death pathways. Theranostics. 2021;11:7735-7754 pubmed publisher
western blot; mouse; loading ...; fig 2a	Nozaki Y, Hikita H, Tanaka S, Fukumoto K, Urabe M, Sato K, et al. Persistent hepatocyte apoptosis promotes tumorigenesis from diethylnitrosamine-transformed hepatocytes through increased oxidative stress, independent of compensatory liver regeneration. Sci Rep. 2021;11:3363 pubmed publisher
western blot; mouse; 1:500; loading ...; fig 6a	Modi J, Menzie Suderam J, Xu H, Trujillo P, Medley K, Marshall M, et al. Mode of action of granulocyte-colony stimulating factor (G-CSF) as a novel therapy for stroke in a mouse model. J Biomed Sci. 2020;27:19 pubmed publisher
western blot; human; loading ...; fig 2b	Park S, Jwa E, Shin S, Ju E, Park I, Pak J, et al. Ibulocydine sensitizes human hepatocellular carcinoma cells to TRAIL-induced apoptosis via calpain-mediated Bax cleavage. Int J Biochem Cell Biol. 2017;83:47-55 pubmed publisher
western blot; human; 1:1000; loading ...; fig 5a	Wei R, Lin S, Wu W, Chen L, Li C, Chen H, et al. A microtubule inhibitor, ABT-751, induces autophagy and delays apoptosis in Huh-7 cells. Toxicol Appl Pharmacol. 2016;311:88-98 pubmed publisher
western blot; human; loading ...; fig 4a	Zhao J, Niu X, Li X, Edwards H, Wang G, Wang Y, et al. Inhibition of CHK1 enhances cell death induced by the Bcl-2-selective inhibitor ABT-199 in acute myeloid leukemia cells. Oncotarget. 2016;7:34785-99 pubmed publisher
western blot; human; fig 3	O Neill K, Huang K, Zhang J, Chen Y, Luo X. Inactivation of prosurvival Bcl-2 proteins activates Bax/Bak through the outer mitochondrial membrane. Genes Dev. 2016;30:973-88 pubmed publisher
western blot; human; fig 1	Gilormini M, Malesys C, Armandy E, Manas P, Guy J, Magne N, et al. Preferential targeting of cancer stem cells in the radiosensitizing effect of ABT-737 on HNSCC. Oncotarget. 2016;7:16731-44 pubmed publisher
	Kale J, Kutuk O, Brito G, Andrews T, Leber B, Letai A, et al. Phosphorylation switches Bax from promoting to inhibiting apoptosis thereby increasing drug resistance. EMBO Rep. 2018;19: pubmed publisher
	Kueh H, Zhu Y, Shi J. A simplified Bcl-2 network model reveals quantitative determinants of cell-to-cell variation in sensitivity to anti-mitotic chemotherapeutics. Sci Rep. 2016;6:36585 pubmed publisher
	Klanova M, Andera L, Brazina J, Svadlenka J, Benesova S, Soukup J, et al. Targeting of BCL2 Family Proteins with ABT-199 and Homoharringtonine Reveals BCL2- and MCL1-Dependent Subgroups of Diffuse Large B-Cell Lymphoma. Clin Cancer Res. 2016;22:1138-49 pubmed publisher

product information

SKU :

3814S

Product-Name :

Bak Antibody

Size :

100 ul

Price-(USD) :

235 USD

Species-x-Reactivity :

H, M, R, Mk

Applications :

Western blot

Product-Category :

Apoptosis

Shipping-Temp :

AMBIENT

Storage-Temp :

-20°C

Product-Type :

Polyclonal Antibody

MW :

Host :

Rabbit

Target :

Bak1

Primary-Protein :

Bak1

Alt-Names :

Apoptosis regulator BAK,BAK,BAK-LIKE,BAK1,BCL2-antagonist/killer 1,BCL2-like 7 protein,BCL2L7,Bcl-2 homologous antagonist/killer,Bcl-2-like protein 7,Bcl2-L-7,CDN1,MGC117255,MGC3887,pro-apoptotic protein BAK

more info or order :

Cell Signaling Technology product webpage