product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-Jak2 (Tyr1007/1008) (C80C3) Rabbit mAb
catalog :
3776S
quantity :
100 ul
price :
274 USD
clonality :
monoclonal
host :
rabbit
antigen modification :
phosphorylated
reactivity :
human, mouse, rat, cow
application :
western blot
more info or order :
Cell Signaling Technology product webpage
citations: 12
Published Application/Species/DilutionReference
  • western blot; mouse; fig s5
Krause C, Popp O, Thirunarayanan N, Dittmar G, Lipp M, Müller G. MicroRNA-34a promotes genomic instability by a broad suppression of genome maintenance mechanisms downstream of the oncogene KSHV-vGPCR. Oncotarget. 2016;7:10414-32 pubmed publisher
  • western blot; human; fig 2d
Roncero A, Lopez-Nieva P, Cobos-Fernández M, Villa-Morales M, González-Sánchez L, Lopez-Lorenzo J, et al. Contribution of JAK2 mutations to T-cell lymphoblastic lymphoma development. Leukemia. 2016;30:94-103 pubmed publisher
  • western blot; rat; fig 2
Zhang Y, Hu S, Chen Y, Guo M, Wang S. Hepatocyte growth factor inhibits hypoxia/reoxygenation-induced activation of xanthine oxidase in endothelial cells through the JAK2 signaling pathway. Int J Mol Med. 2016;38:1055-62 pubmed publisher
  • western blot; human; fig 3
Wu L, Guo L, Liang Y, Liu X, Jiang L, Wang L. Curcumin suppresses stem-like traits of lung cancer cells via inhibiting the JAK2/STAT3 signaling pathway. Oncol Rep. 2015;34:3311-7 pubmed publisher
  • western blot; mouse
Huang S, Lee C, Wang H, Chang Y, Lin C, Chen C, et al. 6-Dehydrogingerdione restrains lipopolysaccharide-induced inflammatory responses in RAW 264.7 macrophages. J Agric Food Chem. 2014;62:9171-9 pubmed publisher
Russell M, Cooper A, Dhayal S, Morgan N. Differential effects of interleukin-13 and interleukin-6 on Jak/STAT signaling and cell viability in pancreatic β-cells. Islets. 2013;5:95-105 pubmed publisher
Zhang H, Yea K, Xie J, Ruiz D, Wilson I, Lerner R. Selecting agonists from single cells infected with combinatorial antibody libraries. Chem Biol. 2013;20:734-41 pubmed publisher
Bhattacharyya S, Zhao Y, Kay T, Muglia L. Glucocorticoids target suppressor of cytokine signaling 1 (SOCS1) and type 1 interferons to regulate Toll-like receptor-induced STAT1 activation. Proc Natl Acad Sci U S A. 2011;108:9554-9 pubmed publisher
Metlakunta A, Sahu M, Yasukawa H, Dhillon S, Belsham D, Yoshimura A, et al. Neuronal suppressor of cytokine signaling-3 deficiency enhances hypothalamic leptin-dependent phosphatidylinositol 3-kinase signaling. Am J Physiol Regul Integr Comp Physiol. 2011;300:R1185-93 pubmed publisher
Ahluwalia M, Donovan H, Singh N, Butcher L, Erusalimsky J. Anagrelide represses GATA-1 and FOG-1 expression without interfering with thrombopoietin receptor signal transduction. J Thromb Haemost. 2010;8:2252-61 pubmed publisher
Singh S, Verma R, Pradeep A, Leu K, Mortensen R, Young P, et al. Dynamic ligand modulation of EPO receptor pools, and dysregulation by polycythemia-associated EPOR alleles. PLoS ONE. 2012;7:e29064 pubmed publisher
Weigert O, Lane A, Bird L, Kopp N, Chapuy B, Van Bodegom D, et al. Genetic resistance to JAK2 enzymatic inhibitors is overcome by HSP90 inhibition. J Exp Med. 2012;209:259-73 pubmed publisher
product information
SKU :
3776S
Product-Name :
Phospho-Jak2 (Tyr1007/1008) (C80C3) Rabbit mAb
Size :
100 ul
Price-(USD) :
274 USD
Species-x-Reactivity :
H, M, R, (Mk, B)
Applications :
Western blot
Product-Category :
Immunology and Inflammation
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
125
Host :
Rabbit
Target :
Jak2 (Tyr1007/Tyr1008) phosphate
Primary-Protein :
JAK2
Alt-Names :
JAK-2,JAK2,JTK10,Janus kinase 2,Janus kinase 2 (a protein tyrosine kinase),Tyrosine-protein kinase JAK2
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.