product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-ASK1 (Thr845) Antibody
catalog :
3765
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
antigen modification :
phosphorylated
reactivity :
human, mouse
application :
western blot
citations: 14
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 6a
Chen X, Ma W, Yao Y, Zhang Q, Li J, Wu X, et al. Serum deprivation-response protein induces apoptosis in hepatocellular carcinoma through ASK1-JNK/p38 MAPK pathways. Cell Death Dis. 2021;12:425 pubmed publisher
  • western blot; mouse; loading ...; fig 6f
Chen S, Zhang H, Li J, Shi J, Tang H, Zhang Y, et al. Tripartite Motif-Containing 27 Attenuates Liver Ischemia/Reperfusion Injury by Suppressing Transforming Growth Factor β-Activated Kinase 1 (TAK1) by TAK1 Binding Protein 2/3 Degradation. Hepatology. 2021;73:738-758 pubmed publisher
  • western blot; human; loading ...; fig 1a
Park H, Shin D, Sim J, Aum S, Lee M. IRE1α kinase-mediated unconventional protein secretion rescues misfolded CFTR and pendrin. Sci Adv. 2020;6:eaax9914 pubmed publisher
  • western blot; mouse; fig s10
Wassermann Dozorets R, Rubinstein M. C/EBPβ LIP augments cell death by inducing osteoglycin. Cell Death Dis. 2017;8:e2733 pubmed publisher
  • western blot; human; 1:1000; fig 3d
Lin C, Lin W, Cho R, Wang C, Hsiao L, Yang C. TNF-?-Induced cPLA2 Expression via NADPH Oxidase/Reactive Oxygen Species-Dependent NF-?B Cascade on Human Pulmonary Alveolar Epithelial Cells. Front Pharmacol. 2016;7:447 pubmed
  • western blot; mouse; fig 5b
  • western blot; human; fig 5b
Dunnill C, Ibraheem K, Mohamed A, Southgate J, Georgopoulos N. A redox state-dictated signalling pathway deciphers the malignant cell specificity of CD40-mediated apoptosis. Oncogene. 2017;36:2515-2528 pubmed publisher
  • western blot; human; 1:100; fig st1
Treindl F, Ruprecht B, Beiter Y, Schultz S, Döttinger A, Staebler A, et al. A bead-based western for high-throughput cellular signal transduction analyses. Nat Commun. 2016;7:12852 pubmed publisher
  • western blot; human; loading ...; fig 5a
Beauvais D, Jung O, Yang Y, Sanderson R, Rapraeger A. Syndecan-1 (CD138) Suppresses Apoptosis in Multiple Myeloma by Activating IGF1 Receptor: Prevention by SynstatinIGF1R Inhibits Tumor Growth. Cancer Res. 2016;76:4981-93 pubmed publisher
  • western blot; mouse; loading ...; fig 7c
Yu Z, Chen T, Li X, Yang M, Tang S, Zhu X, et al. Lys29-linkage of ASK1 by Skp1-Cullin 1-Fbxo21 ubiquitin ligase complex is required for antiviral innate response. elife. 2016;5: pubmed publisher
  • western blot; human; 1:750; fig s4
Federspiel J, Codreanu S, Palubinsky A, Winland A, Betanzos C, McLaughlin B, et al. Assembly Dynamics and Stoichiometry of the Apoptosis Signal-regulating Kinase (ASK) Signalosome in Response to Electrophile Stress. Mol Cell Proteomics. 2016;15:1947-61 pubmed publisher
  • western blot; human; loading ...; fig 3a
Lv H, Zhang Z, Wu X, Wang Y, Li C, Gong W, et al. Preclinical Evaluation of Liposomal C8 Ceramide as a Potent anti-Hepatocellular Carcinoma Agent. PLoS ONE. 2016;11:e0145195 pubmed publisher
Giuliano C, Lin A, Smith J, Palladino A, Sheltzer J. MELK expression correlates with tumor mitotic activity but is not required for cancer growth. elife. 2018;7: pubmed publisher
Tang K, Zhao Y, Li H, Zhu M, Li W, Liu W, et al. Translocase of Inner Membrane 50 Functions as a Novel Protective Regulator of Pathological Cardiac Hypertrophy. J Am Heart Assoc. 2017;6: pubmed publisher
Lee C, Shin S, Lee J, Seo H, Lim K, Kim H, et al. MicroRNA-Mediated Down-Regulation of Apoptosis Signal-Regulating Kinase 1 (ASK1) Attenuates the Apoptosis of Human Mesenchymal Stem Cells (MSCs) Transplanted into Infarcted Heart. Int J Mol Sci. 2016;17: pubmed
product information
SKU :
3765S
Product-Name :
Phospho-ASK1 (Thr845) Antibody
Size :
100 ul
Price-(USD) :
274 USD
Species-x-Reactivity :
H, (M)
Applications :
Western blot
Product-Category :
MAP Kinase Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
155
Host :
Rabbit
Target :
ASK1 (Thr918) phosphate
Primary-Protein :
ASK1
Alt-Names :
ASK-1,ASK1,MAP/ERK kinase kinase 5,MAP3K5,MAPK/ERK kinase kinase 5,MAPKKK5,MEK kinase 5,MEKK 5,MEKK5,Mitogen-activated protein kinase kinase kinase 5 variant,apoptosis signal regulating kinase 1,apoptosis signal-regulating kinase 1,mitogen-activated protein kinase kinase kinase 5
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.