product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
SHP-1 (C14H6) Rabbit mAb
catalog :
3759
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
C14H6
reactivity :
human, mouse, rat
application :
western blot, immunoprecipitation, immunohistochemistry - frozen section
citations: 11
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:10,000; loading ...; fig s1
Pluvinage J, Haney M, Smith B, Sun J, Iram T, Bonanno L, et al. CD22 blockade restores homeostatic microglial phagocytosis in ageing brains. Nature. 2019;568:187-192 pubmed publisher
  • western blot; mouse; loading ...; fig s4g
Grohmann M, Wiede F, Dodd G, Gurzov E, Ooi G, Butt T, et al. Obesity Drives STAT-1-Dependent NASH and STAT-3-Dependent HCC. Cell. 2018;175:1289-1306.e20 pubmed publisher
  • western blot; human; 1:1000; loading ...
Deng M, Gui X, Kim J, Xie L, Chen W, Li Z, et al. LILRB4 signalling in leukaemia cells mediates T cell suppression and tumour infiltration. Nature. 2018;562:605-609 pubmed publisher
  • western blot; mouse; 1:1000; fig 1
Uto T, Fukaya T, Takagi H, Arimura K, Nakamura T, Kojima N, et al. Clec4A4 is a regulatory receptor for dendritic cells that impairs inflammation and T-cell immunity. Nat Commun. 2016;7:11273 pubmed publisher
  • immunohistochemistry - frozen section; rat; 1:1500
Chen Z, Shojaee S, Buchner M, Geng H, Lee J, Klemm L, et al. Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia. Nature. 2015;521:357-61 pubmed publisher
Deng H, Hu N, Wang C, Chen M, Zhao M. Interaction between CD177 and platelet endothelial cell adhesion molecule-1 downregulates membrane-bound proteinase-3 (PR3) expression on neutrophils and attenuates neutrophil activation induced by PR3-ANCA. Arthritis Res Ther. 2018;20:213 pubmed publisher
Dutta D, Barr V, Akpan I, Mittelstadt P, Singha L, Samelson L, et al. Recruitment of calcineurin to the TCR positively regulates T cell activation. Nat Immunol. 2017;18:196-204 pubmed publisher
Amantini C, Morelli M, Santoni M, Soriani A, Cardinali C, Farfariello V, et al. Sorafenib induces cathepsin B-mediated apoptosis of bladder cancer cells by regulating the Akt/PTEN pathway. The Akt inhibitor, perifosine, enhances the sorafenib-induced cytotoxicity against bladder cancer cells. Oncoscience. 2015;2:395-409 pubmed
Lanahan A, Zhang X, Fantin A, Zhuang Z, Rivera Molina F, Speichinger K, et al. The neuropilin 1 cytoplasmic domain is required for VEGF-A-dependent arteriogenesis. Dev Cell. 2013;25:156-68 pubmed publisher
Borhis G, Ahmed P, Mbiribindi B, Naiyer M, Davis D, Purbhoo M, et al. A peptide antagonist disrupts NK cell inhibitory synapse formation. J Immunol. 2013;190:2924-30 pubmed publisher
Blaser C, Wittwer M, Grandgirard D, Leib S. Adjunctive dexamethasone affects the expression of genes related to inflammation, neurogenesis and apoptosis in infant rat pneumococcal meningitis. PLoS ONE. 2011;6:e17840 pubmed publisher
product information
SKU :
3759S
Product-Name :
SHP-1 (C14H6) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, (R)
Applications :
Western blot
Product-Category :
Immunology and Inflammation
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
68
Host :
Rabbit
Target :
SHP-1
Primary-Protein :
SHP-1
Alt-Names :
HCP,HCPH,HPTP1C,Hematopoietic cell protein-tyrosine phosphatase,PTN6,PTP-1C,PTP1C,PTPN6,Protein-tyrosine phosphatase 1C,Protein-tyrosine phosphatase SHP-1,SH-PTP1,SHP-1,SHP-1L,SHP1,Tyrosine-protein phosphatase non-receptor type 6,hematopoietic cell phosphatase,protein tyrosine phosphatase, non-receptor type 6
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.