| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot; scFv; 1:2000
| Liu M, Li Y, Liu A, Li R, Su Y, Du J, et al. The exon junction complex regulates the splicing of cell polarity gene dlg1 to control Wingless signaling in development. elife. 2016;5: pubmed publisher |
- immunoprecipitation; scFv; 1:1000; fig s5
- western blot; scFv; 1:1000; fig s5
| Durand S, Franks T, Lykke Andersen J. Hyperphosphorylation amplifies UPF1 activity to resolve stalls in nonsense-mediated mRNA decay. Nat Commun. 2016;7:12434 pubmed publisher |
- western blot; human; fig 1
| Raducu M, Fung E, Serres S, Infante P, Barberis A, Fischer R, et al. SCF (Fbxl17) ubiquitylation of Sufu regulates Hedgehog signaling and medulloblastoma development. EMBO J. 2016;35:1400-16 pubmed publisher |
- immunocytochemistry; rat; fig 2a
- immunoprecipitation; African green monkey; fig 10g
- western blot; African green monkey; 1:1000; fig 10g
| Shih Y, Hsueh Y. VCP and ATL1 regulate endoplasmic reticulum and protein synthesis for dendritic spine formation. Nat Commun. 2016;7:11020 pubmed publisher |
- immunoprecipitation; mouse; fig 3c
| Zhang Q, Zhao K, Shen Q, Han Y, Gu Y, Li X, et al. Tet2 is required to resolve inflammation by recruiting Hdac2 to specifically repress IL-6. Nature. 2015;525:389-393 pubmed publisher |
- western blot; scFv; fig 3
| Ibeawuchi S, Agbor L, Quelle F, Sigmund C. Hypertension-causing Mutations in Cullin3 Protein Impair RhoA Protein Ubiquitination and Augment the Association with Substrate Adaptors. J Biol Chem. 2015;290:19208-17 pubmed publisher |
- western blot; scFv; fig 1
| Lim J, Lachenmayer M, Wu S, Liu W, Kundu M, Wang R, et al. Proteotoxic stress induces phosphorylation of p62/SQSTM1 by ULK1 to regulate selective autophagic clearance of protein aggregates. PLoS Genet. 2015;11:e1004987 pubmed publisher |
- western blot; scFv; fig 6
| Gee H, Kim J, Lee M. Analysis of conventional and unconventional trafficking of CFTR and other membrane proteins. Methods Mol Biol. 2015;1270:137-54 pubmed publisher |
- western blot; mouse; 1:1000; fig 5,6
| Hsiao H, Hsu T, Liu W, Hsieh W, Chou T, Wu Y, et al. Deltex1 antagonizes HIF-1α and sustains the stability of regulatory T cells in vivo. Nat Commun. 2015;6:6353 pubmed publisher |
| Matsuno M, Horiuchi J, Yuasa Y, Ofusa K, Miyashita T, Masuda T, et al. Long-term memory formation in Drosophila requires training-dependent glial transcription. J Neurosci. 2015;35:5557-65 pubmed publisher |
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| Wang Y, Zhang Y, Zhu Y, Zhang P. Lipolytic inhibitor G0/G1 switch gene 2 inhibits reactive oxygen species production and apoptosis in endothelial cells. Am J Physiol Cell Physiol. 2015;308:C496-504 pubmed publisher |
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| Horbach T, Chi T, Götz C, Sharma S, Juffer A, Dimova E, et al. GSK3β-dependent phosphorylation alters DNA binding, transactivity and half-life of the transcription factor USF2. PLoS ONE. 2014;9:e107914 pubmed publisher |
| Han L, Diehl A, Nguyen N, Korangath P, Teo W, Cho S, et al. The Notch pathway inhibits TGFβ signaling in breast cancer through HEYL-mediated crosstalk. Cancer Res. 2014;74:6509-18 pubmed publisher |
| Ali M, Chernova T, Newnam G, Yin L, Shanks J, Karpova T, et al. Stress-dependent proteolytic processing of the actin assembly protein Lsb1 modulates a yeast prion. J Biol Chem. 2014;289:27625-39 pubmed publisher |
| Chen X, Chinchilla P, Fombonne J, Ho L, Guix C, Keen J, et al. Patched-1 proapoptotic activity is downregulated by modification of K1413 by the E3 ubiquitin-protein ligase Itchy homolog. Mol Cell Biol. 2014;34:3855-66 pubmed publisher |
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| Alcántara Hernández R, Hernández Méndez A, García Sáinz J. The phosphoinositide-dependent protein kinase 1 inhibitor, UCN-01, induces fragmentation: possible role of metalloproteinases. Eur J Pharmacol. 2014;740:88-96 pubmed publisher |
| Hsu T, Hsiao H, Wu P, Liu W, Lai M. Deltex1 promotes protein kinase C? degradation and sustains Casitas B-lineage lymphoma expression. J Immunol. 2014;193:1672-80 pubmed publisher |
| Tsai C, Larson C, Safaei R, Howell S. Molecular modulation of the copper and cisplatin transport function of CTR1 and its interaction with IRS-4. Biochem Pharmacol. 2014;90:379-87 pubmed publisher |
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| Yu F, Hong Y, Qu J, Chen F, Li T. The large intracellular loop of ptch1 mediates the non-canonical Hedgehog pathway through cyclin B1 in nevoid basal cell carcinoma syndrome. Int J Mol Med. 2014;34:507-12 pubmed publisher |
| Santiago Lima A, Hoogeveen Westerveld M, Nakashima A, Maat Kievit A, van den Ouweland A, Halley D, et al. Identification of regions critical for the integrity of the TSC1-TSC2-TBC1D7 complex. PLoS ONE. 2014;9:e93940 pubmed publisher |
| Herbáth M, Szekeres Z, Kovesdi D, Papp K, Erdei A, Prechl J. Coadministration of antigen-conjugated and free CpG: effects of in vitro and in vivo interactions in a murine model. Immunol Lett. 2014;160:178-85 pubmed publisher |
| Verma P, Pfister J, Mallick S, D Mello S. HSF1 protects neurons through a novel trimerization- and HSP-independent mechanism. J Neurosci. 2014;34:1599-612 pubmed publisher |
| Hattori T, Uchida C, Takahashi H, Yamamoto N, Naito M, Taya Y. Distinct and site-specific phosphorylation of the retinoblastoma protein at serine 612 in differentiated cells. PLoS ONE. 2014;9:e86709 pubmed publisher |
| Oshiro N, Rapley J, Avruch J. Amino acids activate mammalian target of rapamycin (mTOR) complex 1 without changing Rag GTPase guanyl nucleotide charging. J Biol Chem. 2014;289:2658-74 pubmed publisher |
| Wu Y, Kuo W, Wu Y, Yang K, Chen S, Jiang S, et al. Participation of c-FLIP in NLRP3 and AIM2 inflammasome activation. Cell Death Differ. 2014;21:451-61 pubmed publisher |
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| Zheng Y, Wang Z, Bie W, Brauer P, Perez White B, Li J, et al. PTK6 activation at the membrane regulates epithelial-mesenchymal transition in prostate cancer. Cancer Res. 2013;73:5426-37 pubmed publisher |
| Yu F, Gao W, Yokochi T, Suenaga Y, Ando K, Ohira M, et al. RUNX3 interacts with MYCN and facilitates protein degradation in neuroblastoma. Oncogene. 2014;33:2601-9 pubmed publisher |
| Smith V, Sharma N, Watkins R, Read M, Ryan G, Kwan P, et al. Manipulation of PBF/PTTG1IP phosphorylation status; a potential new therapeutic strategy for improving radioiodine uptake in thyroid and other tumors. J Clin Endocrinol Metab. 2013;98:2876-86 pubmed publisher |
| Takasugi N, Sasaki T, Ebinuma I, Osawa S, Isshiki H, Takeo K, et al. FTY720/fingolimod, a sphingosine analogue, reduces amyloid-? production in neurons. PLoS ONE. 2013;8:e64050 pubmed publisher |
| Duong C, Westwood J, Yong C, Murphy A, Devaud C, John L, et al. Engineering T cell function using chimeric antigen receptors identified using a DNA library approach. PLoS ONE. 2013;8:e63037 pubmed publisher |
| Sarkar D, Edwards S, Mauser J, Suarez A, Serowoky M, Hudok N, et al. Increased redox-sensitive green fluorescent protein reduction potential in the endoplasmic reticulum following glutathione-mediated dimerization. Biochemistry. 2013;52:3332-45 pubmed publisher |
| Kim J, Huh J, Hwang M, Kwon E, Jung D, Brinkmann M, et al. Acidic amino acid residues in the juxtamembrane region of the nucleotide-sensing TLRs are important for UNC93B1 binding and signaling. J Immunol. 2013;190:5287-95 pubmed publisher |
| Schäfer A, Schubert S, Gratchev A, Seebode C, Apel A, Laspe P, et al. Characterization of three XPG-defective patients identifies three missense mutations that impair repair and transcription. J Invest Dermatol. 2013;133:1841-9 pubmed publisher |
| Hughes C, Sinha U, Pandey A, Eble J, O Callaghan C, Watson S. Critical Role for an acidic amino acid region in platelet signaling by the HemITAM (hemi-immunoreceptor tyrosine-based activation motif) containing receptor CLEC-2 (C-type lectin receptor-2). J Biol Chem. 2013;288:5127-35 pubmed publisher |
| Panjwani N, Mulvihill E, Longuet C, Yusta B, Campbell J, Brown T, et al. GLP-1 receptor activation indirectly reduces hepatic lipid accumulation but does not attenuate development of atherosclerosis in diabetic male ApoE(-/-) mice. Endocrinology. 2013;154:127-39 pubmed publisher |
| Hibino T, Sakaguchi M, Miyamoto S, Yamamoto M, Motoyama A, Hosoi J, et al. S100A9 is a novel ligand of EMMPRIN that promotes melanoma metastasis. Cancer Res. 2013;73:172-83 pubmed publisher |
| Vajjhala P, Mirams R, Hill J. Multiple binding sites on the pyrin domain of ASC protein allow self-association and interaction with NLRP3 protein. J Biol Chem. 2012;287:41732-43 pubmed publisher |
| Zheng Y, Gierut J, Wang Z, Miao J, Asara J, Tyner A. Protein tyrosine kinase 6 protects cells from anoikis by directly phosphorylating focal adhesion kinase and activating AKT. Oncogene. 2013;32:4304-12 pubmed publisher |
| Chen Y, Chen C, Hu H, Hsueh Y. CTTNBP2, but not CTTNBP2NL, regulates dendritic spinogenesis and synaptic distribution of the striatin-PP2A complex. Mol Biol Cell. 2012;23:4383-92 pubmed publisher |
| Scheib J, Sullivan C, Carter B. Jedi-1 and MEGF10 signal engulfment of apoptotic neurons through the tyrosine kinase Syk. J Neurosci. 2012;32:13022-31 pubmed |
| Tamura H, Kawata M, Hamaguchi S, Ishikawa Y, Shiosaka S. Processing of neuregulin-1 by neuropsin regulates GABAergic neuron to control neural plasticity of the mouse hippocampus. J Neurosci. 2012;32:12657-72 pubmed publisher |
| Sun J, Sun Q, Brown M, Dudgeon C, Chandler J, Xu X, et al. The multi-targeted kinase inhibitor sunitinib induces apoptosis in colon cancer cells via PUMA. PLoS ONE. 2012;7:e43158 pubmed publisher |
| Walker K, Kang E, Whalen M, Shen Y, Tesco G. Depletion of GGA1 and GGA3 mediates postinjury elevation of BACE1. J Neurosci. 2012;32:10423-37 pubmed publisher |
| Jeyaraj S, Unger N, Eid A, Mitra S, Paul El Dahdah N, Quilliam L, et al. Cyclic AMP-Rap1A signaling activates RhoA to induce ?(2c)-adrenoceptor translocation to the cell surface of microvascular smooth muscle cells. Am J Physiol Cell Physiol. 2012;303:C499-511 pubmed publisher |
| Emami Nemini A, Gohla A, Urlaub H, Lohse M, Klenk C. The guanine nucleotide exchange factor Vav2 is a negative regulator of parathyroid hormone receptor/Gq signaling. Mol Pharmacol. 2012;82:217-25 pubmed publisher |
| Smith V, Read M, Turnell A, Sharma N, Lewy G, Fong J, et al. PTTG-binding factor (PBF) is a novel regulator of the thyroid hormone transporter MCT8. Endocrinology. 2012;153:3526-36 pubmed publisher |
| Gutekunst C, Stewart E, Franz C, English A, Gross R. PlexinA4 distribution in the adult rat spinal cord and dorsal root ganglia. J Chem Neuroanat. 2012;44:1-13 pubmed publisher |
| Prox J, Willenbrock M, Weber S, Lehmann T, Schmidt Arras D, Schwanbeck R, et al. Tetraspanin15 regulates cellular trafficking and activity of the ectodomain sheddase ADAM10. Cell Mol Life Sci. 2012;69:2919-32 pubmed publisher |
| Huet S, Fanget I, Jouannot O, Meireles P, Zeiske T, Larochette N, et al. Myrip couples the capture of secretory granules by the actin-rich cell cortex and their attachment to the plasma membrane. J Neurosci. 2012;32:2564-77 pubmed publisher |
| Dastidar S, Bardai F, Ma C, Price V, Rawat V, Verma P, et al. Isoform-specific toxicity of Mecp2 in postmitotic neurons: suppression of neurotoxicity by FoxG1. J Neurosci. 2012;32:2846-55 pubmed publisher |
| Pratt Z, Zhang J, Sugden B. The latent membrane protein 1 (LMP1) oncogene of Epstein-Barr virus can simultaneously induce and inhibit apoptosis in B cells. J Virol. 2012;86:4380-93 pubmed publisher |
| Eisenach P, de Sampaio P, Murphy G, Roghi C. Membrane type 1 matrix metalloproteinase (MT1-MMP) ubiquitination at Lys581 increases cellular invasion through type I collagen. J Biol Chem. 2012;287:11533-45 pubmed publisher |
| Mórotz G, De Vos K, Vagnoni A, Ackerley S, Shaw C, Miller C. Amyotrophic lateral sclerosis-associated mutant VAPBP56S perturbs calcium homeostasis to disrupt axonal transport of mitochondria. Hum Mol Genet. 2012;21:1979-88 pubmed publisher |
| Li X, Lu Y, Liang K, Hsu J, Albarracin C, Mills G, et al. Brk/PTK6 sustains activated EGFR signaling through inhibiting EGFR degradation and transactivating EGFR. Oncogene. 2012;31:4372-83 pubmed publisher |
| Manser C, Vagnoni A, Guillot F, Davies J, Miller C. Cdk5/p35 phosphorylates lemur tyrosine kinase-2 to regulate protein phosphatase-1C phosphorylation and activity. J Neurochem. 2012;121:343-8 pubmed publisher |
| Tanida I, Yamasaki M, Komatsu M, Ueno T. The FAP motif within human ATG7, an autophagy-related E1-like enzyme, is essential for the E2-substrate reaction of LC3 lipidation. Autophagy. 2012;8:88-97 pubmed publisher |
| Kim M, Ju J, Jang K, Oh S, Song J, Kim C, et al. Protein kinase C? negatively regulates Notch1-dependent transcription via a kinase-independent mechanism in vitro. Biochim Biophys Acta. 2012;1823:387-97 pubmed publisher |
| Pfreimer M, Vatter P, Langer T, Wieland T, Gierschik P, Moepps B. LARG links histamine-H1-receptor-activated Gq to Rho-GTPase-dependent signaling pathways. Cell Signal. 2012;24:652-63 pubmed publisher |
| Zheng Y, Asara J, Tyner A. Protein-tyrosine kinase 6 promotes peripheral adhesion complex formation and cell migration by phosphorylating p130 CRK-associated substrate. J Biol Chem. 2012;287:148-58 pubmed publisher |
| Kanter J, Tang C, Oram J, Bornfeldt K. Acyl-CoA synthetase 1 is required for oleate and linoleate mediated inhibition of cholesterol efflux through ATP-binding cassette transporter A1 in macrophages. Biochim Biophys Acta. 2012;1821:358-64 pubmed publisher |
| Moon K, Zhang X, Zhou Q, Geahlen R. The protein-tyrosine kinase Syk interacts with the C-terminal region of tensin2. Biochim Biophys Acta. 2012;1823:199-205 pubmed publisher |
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