product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-SHP-2 (Tyr542) Antibody
catalog :
3751
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
antigen modification :
phosphorylated
reactivity :
human, mouse, rat
application :
western blot, immunoprecipitation, other
more info or order :
Cell Signaling Technology product webpage
citations: 8
Published Application/Species/Sample/DilutionReference
  • other; human; loading ...; fig 4c
Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed publisher
  • western blot; mouse; loading ...; fig s5d
Li B, Wang X, Choi I, Wang Y, Liu S, Pham A, et al. miR-146a modulates autoreactive Th17 cell differentiation and regulates organ-specific autoimmunity. J Clin Invest. 2017;127:3702-3716 pubmed publisher
  • western blot; human
Machado Neto J, Lazarini M, Favaro P, de Melo Campos P, Scopim Ribeiro R, Franchi Junior G, et al. ANKHD1 silencing inhibits Stathmin 1 activity, cell proliferation and migration of leukemia cells. Biochim Biophys Acta. 2015;1853:583-93 pubmed publisher
  • western blot; human
Paugh B, Zhu X, Qu C, Endersby R, Diaz A, Zhang J, et al. Novel oncogenic PDGFRA mutations in pediatric high-grade gliomas. Cancer Res. 2013;73:6219-29 pubmed publisher
Davies K, Mahale S, Astling D, Aisner D, Le A, Hinz T, et al. Resistance to ROS1 inhibition mediated by EGFR pathway activation in non-small cell lung cancer. PLoS ONE. 2013;8:e82236 pubmed publisher
Craig J, Mikhailenko I, Noyes N, Migliorini M, Strickland D. The LDL receptor-related protein 1 (LRP1) regulates the PDGF signaling pathway by binding the protein phosphatase SHP-2 and modulating SHP-2- mediated PDGF signaling events. PLoS ONE. 2013;8:e70432 pubmed publisher
Veniant M, Hale C, Helmering J, Chen M, Stanislaus S, Busby J, et al. FGF21 promotes metabolic homeostasis via white adipose and leptin in mice. PLoS ONE. 2012;7:e40164 pubmed publisher
Krall J, Beyer E, MacBeath G. High- and low-affinity epidermal growth factor receptor-ligand interactions activate distinct signaling pathways. PLoS ONE. 2011;6:e15945 pubmed publisher
product information
SKU :
3751S
Product-Name :
Phospho-SHP-2 (Tyr542) Antibody
Size :
100 ul
Price-(USD) :
274 USD
Species-x-Reactivity :
H, M, R, (Mk, C, X)
Applications :
Immunoprecipitation
Product-Category :
MAP Kinase Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
72
Host :
Rabbit
Target :
SHP-2 (Tyr546) phosphate
Primary-Protein :
SHP-2
Alt-Names :
BPTP3,CFC,MGC14433,NS1,PTN11,PTP-1D,PTP-2C,PTP2C,PTPN11,Protein-tyrosine phosphatase 1D,Protein-tyrosine phosphatase 2C,SH-PTP2,SH-PTP3,SHP-2,SHPTP2,Shp2,Tyrosine-protein phosphatase non-receptor type 11,protein tyrosine phosphatase, non-receptor type 11,protein tyrosine phosphatase-2
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.