product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Rig-I (D14G6) Rabbit mAb
catalog :
3743S
quantity :
100 ul
price :
235 USD
clonality :
monoclonal
host :
rabbit
reactivity :
human, mouse
application :
western blot, immunoprecipitation
citations: 10
Published Application/Species/DilutionReference
  • western blot; human; fig 1
Hou Z, Zhang J, Han Q, Su C, Qu J, Xu D, et al. Hepatitis B virus inhibits intrinsic RIG-I and RIG-G immune signaling via inducing miR146a. Sci Rep. 2016;6:26150 pubmed publisher
  • western blot; Hepatitis C virus
Panas M, Kedersha N, McInerney G. Methods for the characterization of stress granules in virus infected cells. Methods. 2015;90:57-64 pubmed publisher
  • western blot; mouse; fig 1
West A, Khoury-Hanold W, Staron M, Tal M, Pineda C, Lang S, et al. Mitochondrial DNA stress primes the antiviral innate immune response. Nature. 2015;520:553-7 pubmed publisher
  • western blot; mouse
Yang S, Deng P, Zhu Z, Zhu J, Wang G, Zhang L, et al. Adenosine deaminase acting on RNA 1 limits RIG-I RNA detection and suppresses IFN production responding to viral and endogenous RNAs. J Immunol. 2014;193:3436-45 pubmed publisher
  • western blot; human
Chattergoon M, Latanich R, Quinn J, Winter M, Buckheit R, Blankson J, et al. HIV and HCV activate the inflammasome in monocytes and macrophages via endosomal Toll-like receptors without induction of type 1 interferon. PLoS Pathog. 2014;10:e1004082 pubmed publisher
  • western blot; human; 1:1,000
Xia M, Gonzalez P, Li C, Meng G, Jiang A, Wang H, et al. Mitophagy enhances oncolytic measles virus replication by mitigating DDX58/RIG-I-like receptor signaling. J Virol. 2014;88:5152-64 pubmed publisher
  • immunoprecipitation; human; fig 3
Liedmann S, Hrincius E, Guy C, Anhlan D, Dierkes R, Carter R, et al. Viral suppressors of the RIG-I-mediated interferon response are pre-packaged in influenza virions. Nat Commun. 2014;5:5645 pubmed publisher
Kolokoltsova O, Grant A, Huang C, Smith J, Poussard A, Tian B, et al. RIG-I enhanced interferon independent apoptosis upon Junin virus infection. PLoS ONE. 2014;9:e99610 pubmed publisher
Chiba Y, Mizoguchi I, Mitobe K, Higuchi K, Nagai H, Nishigori C, et al. IL-27 enhances the expression of TRAIL and TLR3 in human melanomas and inhibits their tumor growth in cooperation with a TLR3 agonist poly(I:C) partly in a TRAIL-dependent manner. PLoS ONE. 2013;8:e76159 pubmed publisher
Wang Y, Tong X, Ye X. Ndfip1 negatively regulates RIG-I-dependent immune signaling by enhancing E3 ligase Smurf1-mediated MAVS degradation. J Immunol. 2012;189:5304-13 pubmed publisher
product information
SKU :
3743S
Product-Name :
Rig-I (D14G6) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Immunoprecipitation
Product-Category :
Immunology and Inflammation
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
102
Host :
Rabbit
Target :
RIG-I
Primary-Protein :
DDX58
Alt-Names :
DDX58,DEAD (Asp-Glu-Ala-Asp) box polypeptide 58,DEAD box protein 58,DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide,DKFZp434J1111,DKFZp686N19181,FLJ13599,Probable ATP-dependent RNA helicase DDX58,RIG-1,RIG-I,RNA helicase RIG-I,Retinoic acid-inducible gene 1 protein,Retinoic acid-inducible gene I protein,retinoic acid inducible gene I
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.