product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
E2F-1 Antibody
catalog :
3742
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunoprecipitation, chromatin immunoprecipitation
more info or order :
Cell Signaling Technology product webpage
citations: 14
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; human; loading ...; fig s3e
Xu Q, Ge Q, Zhou Y, Yang B, Yang Q, Jiang S, et al. MELK promotes Endometrial carcinoma progression via activating mTOR signaling pathway. EBioMedicine. 2020;51:102609 pubmed publisher
  • western blot; human; loading ...; fig 1
Reuther C, Heinzle V, Nölting S, Herterich S, Hahner S, Halilovic E, et al. The HDM2 (MDM2) Inhibitor NVP-CGM097 Inhibits Tumor Cell Proliferation and Shows Additive Effects with 5-Fluorouracil on the p53-p21-Rb-E2F1 Cascade in the p53wild type Neuroendocrine Tumor Cell Line GOT1. Neuroendocrinology. 2018;106:1-19 pubmed publisher
  • western blot; human; 1:3000; loading ...; fig 7a
Fang J, Coon B, Gillis N, Chen Z, Qiu J, Chittenden T, et al. Shear-induced Notch-Cx37-p27 axis arrests endothelial cell cycle to enable arterial specification. Nat Commun. 2017;8:2149 pubmed publisher
  • western blot; human; fig s3a
Mu P, Zhang Z, Benelli M, Karthaus W, Hoover E, Chen C, et al. SOX2 promotes lineage plasticity and antiandrogen resistance in TP53- and RB1-deficient prostate cancer. Science. 2017;355:84-88 pubmed publisher
  • western blot; human; 1:2000; loading ...; fig 4c
Luo X, Peng J, Su L, Wang D, Yu Y. Fangchinoline inhibits the proliferation of SPC-A-1 lung cancer cells by blocking cell cycle progression. Exp Ther Med. 2016;11:613-618 pubmed
  • western blot; human; 1:1000; fig 3
Ortmann B, Bensaddek D, Carvalhal S, Moser S, Mudie S, Griffis E, et al. CDK-dependent phosphorylation of PHD1 on serine 130 alters its substrate preference in cells. J Cell Sci. 2016;129:191-205 pubmed publisher
Lv W, Yang L, Xu C, Shi Z, Shao J, Xian M, et al. Cadmium Disrupts the Balance between Hydrogen Peroxide and Superoxide Radical by Regulating Endogenous Hydrogen Sulfide in the Root Tip of Brassica rapa. Front Plant Sci. 2017;8:232 pubmed publisher
Hancock J. Harnessing Evolutionary Toxins for Signaling: Reactive Oxygen Species, Nitric Oxide and Hydrogen Sulfide in Plant Cell Regulation. Front Plant Sci. 2017;8:189 pubmed publisher
Ju H, Ying H, Tian T, Ling J, Fu J, Lu Y, et al. Mutant Kras- and p16-regulated NOX4 activation overcomes metabolic checkpoints in development of pancreatic ductal adenocarcinoma. Nat Commun. 2017;8:14437 pubmed publisher
Wu Y, Ma S, Xia Y, Lu Y, Xiao S, Cao Y, et al. Loss of GCN5 leads to increased neuronal apoptosis by upregulating E2F1- and Egr-1-dependent BH3-only protein Bim. Cell Death Dis. 2017;8:e2570 pubmed publisher
Yang C, Li Z, Bhatt T, Dickler M, Giri D, Scaltriti M, et al. Acquired CDK6 amplification promotes breast cancer resistance to CDK4/6 inhibitors and loss of ER signaling and dependence. Oncogene. 2017;36:2255-2264 pubmed publisher
Zhou Y, Frings O, Branca R, Boekel J, Le Sage C, Fredlund E, et al. microRNAs with AAGUGC seed motif constitute an integral part of an oncogenic signaling network. Oncogene. 2017;36:731-745 pubmed publisher
Ankers J, Awais R, Jones N, Boyd J, Ryan S, Adamson A, et al. Dynamic NF-κB and E2F interactions control the priority and timing of inflammatory signalling and cell proliferation. elife. 2016;5: pubmed publisher
Urrego D, Movsisyan N, Ufartes R, Pardo L. Periodic expression of Kv10.1 driven by pRb/E2F1 contributes to G2/M progression of cancer and non-transformed cells. Cell Cycle. 2016;15:799-811 pubmed publisher
product information
SKU :
3742S
Product-Name :
E2F-1 Antibody
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, (R)
Applications :
Chromatin Immunoprecipitation
Product-Category :
Cell Cycle / Checkpoint Control
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
70
Host :
Rabbit
Target :
E2F1
Primary-Protein :
E2F1
Alt-Names :
E2F transcription factor 1,E2F-1,E2F1,PBR3,PRB-binding protein E2F-1,RBAP-1,RBAP1,RBBP-3,RBBP3,RBP3,Retinoblastoma-associated protein 1,Retinoblastoma-binding protein 3,Transcription factor E2F1
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.