Cyclin D2 (D52F9) Rabbit mAb | Cell Signaling Technology 3741 product information

product summary

company name :

Cell Signaling Technology

product type :

antibody

product name :

Cyclin D2 (D52F9) Rabbit mAb

catalog :

3741

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

D52F9

reactivity :

human, mouse, rat

application :

western blot, immunoprecipitation, western blot knockout validation

more info or order :

Cell Signaling Technology product webpage

citations: 16

Published Application/Species/Sample/Dilution	Reference
western blot knockout validation; mouse; loading ...; fig 2a	Zhang J, Bu X, Wang H, Zhu Y, Geng Y, Nihira N, et al. Cyclin D-CDK4 kinase destabilizes PD-L1 via cullin 3-SPOP to control cancer immune surveillance. Nature. 2018;553:91-95 pubmed publisher
western blot; mouse; loading ...; fig 4b	Chen A, Santana A, Doudican N, Roudiani N, Laursen K, Therrien J, et al. MAGE-A3 is a prognostic biomarker for poor clinical outcome in cutaneous squamous cell carcinoma with perineural invasion via modulation of cell proliferation. PLoS ONE. 2020;15:e0241551 pubmed publisher
western blot; human; loading ...; fig 1e	Cornell L, Wander S, Visal T, Wagle N, Shapiro G. MicroRNA-Mediated Suppression of the TGF-β Pathway Confers Transmissible and Reversible CDK4/6 Inhibitor Resistance. Cell Rep. 2019;26:2667-2680.e7 pubmed publisher
western blot; human; 1:1000; loading ...; fig 4c	Li X, Liu F, Lin B, Luo H, Liu M, Wu J, et al. miR?150 inhibits proliferation and tumorigenicity via retarding G1/S phase transition in nasopharyngeal carcinoma. Int J Oncol. 2017;: pubmed publisher
western blot; human; loading ...; fig 2c	Juhasz A, Markel S, Gaur S, Liu H, Lu J, Jiang G, et al. NADPH oxidase 1 supports proliferation of colon cancer cells by modulating reactive oxygen species-dependent signal transduction. J Biol Chem. 2017;292:7866-7887 pubmed publisher
western blot; human; fig s3	Jeong O, Chae Y, Jung H, Park S, Cho S, Kook H, et al. Long noncoding RNA linc00598 regulates CCND2 transcription and modulates the G1 checkpoint. Sci Rep. 2016;6:32172 pubmed publisher
western blot; human; 1:1000; fig 3b	Hanna J, Garcia M, Go J, Finkelstein D, Kodali K, Pagala V, et al. PAX7 is a required target for microRNA-206-induced differentiation of fusion-negative rhabdomyosarcoma. Cell Death Dis. 2016;7:e2256 pubmed publisher
western blot; mouse; 1:2000; fig 2 western blot; human; 1:2000; fig 3	Heaven M, Flint D, Randall S, Sosunov A, Wilson L, Barnes S, et al. Composition of Rosenthal Fibers, the Protein Aggregate Hallmark of Alexander Disease. J Proteome Res. 2016;15:2265-82 pubmed publisher
western blot; human; 1:1000; fig 5	Zeng Q, Tao X, Huang F, Wu T, Wang J, Jiang X, et al. Overexpression of miR-155 promotes the proliferation and invasion of oral squamous carcinoma cells by regulating BCL6/cyclin D2. Int J Mol Med. 2016;37:1274-80 pubmed publisher
western blot; mouse; 1:500; fig s4	Xu C, Ochi H, Fukuda T, Sato S, Sunamura S, Takarada T, et al. Circadian Clock Regulates Bone Resorption in Mice. J Bone Miner Res. 2016;31:1344-55 pubmed publisher
western blot; human; 1:1000; loading ...; fig 5d	Mo X, Cao Q, Liang H, Liu J, Li H, Liu F. MicroRNA-610 suppresses the proliferation of human glioblastoma cells by repressing CCND2 and AKT3. Mol Med Rep. 2016;13:1961-6 pubmed publisher
western blot; mouse	Crowther A, Gama V, Bevilacqua A, Chang S, Yuan H, Deshmukh M, et al. Tonic activation of Bax primes neural progenitors for rapid apoptosis through a mechanism preserved in medulloblastoma. J Neurosci. 2013;33:18098-108 pubmed publisher
	Gieseler Halbach S, Meltendorf S, Pierau M, Weinert S, Heidel F, Fischer T, et al. RSK-mediated nuclear accumulation of the cold-shock Y-box protein-1 controls proliferation of T cells and T-ALL blasts. Cell Death Differ. 2017;24:371-383 pubmed publisher
	Potapova T, Seidel C, Box A, Rancati G, Li R. Transcriptome analysis of tetraploid cells identifies cyclin D2 as a facilitator of adaptation to genome doubling in the presence of p53. Mol Biol Cell. 2016;27:3065-3084 pubmed
	Witt D, Burfeind P, von Hardenberg S, Opitz L, Salinas Riester G, Bremmer F, et al. Valproic acid inhibits the proliferation of cancer cells by re-expressing cyclin D2. Carcinogenesis. 2013;34:1115-24 pubmed publisher
	Balakrishnan A, Chaillet J. Role of the inositol polyphosphate-4-phosphatase type II Inpp4b in the generation of ovarian teratomas. Dev Biol. 2013;373:118-29 pubmed publisher

product information

SKU :

3741S

Product-Name :

Cyclin D2 (D52F9) Rabbit mAb

Size :

100 ul

Price-(USD) :

235 USD

Species-x-Reactivity :

H, M, R

Applications :

Immunoprecipitation

Product-Category :

Cell Cycle / Checkpoint Control

Shipping-Temp :

AMBIENT

Storage-Temp :

-20°C

Product-Type :

Monoclonal Antibody

MW :

Host :

Rabbit

Target :

Cyclin D2

Primary-Protein :

CCND2

Alt-Names :

CCND2,G1/S-specific cyclin D2,G1/S-specific cyclin-D2,KIAK0002,MGC102758,cyclin D2

more info or order :

Cell Signaling Technology product webpage