Beclin-1 Antibody | Cell Signaling Technology 3738S product information

product summary

company name :

Cell Signaling Technology

product type :

antibody

product name :

Beclin-1 Antibody

catalog :

3738S

quantity :

100 ul

price :

235 USD

clonality :

polyclonal

host :

rabbit

reactivity :

human, mouse, rat

application :

western blot, immunoprecipitation, immunohistochemistry - free floating section

more info or order :

Cell Signaling Technology product webpage

citations: 18

Published Application/Species/Dilution	Reference
western blot (knockdown validation); human; 1:1000; fig 4e	Granato M, Gilardini Montani M, Filardi M, Faggioni A, Cirone M. Capsaicin triggers immunogenic PEL cell death, stimulates DCs and reverts PEL-induced immune suppression. Oncotarget. 2015;6:29543-54 pubmed publisher
western blot (knockdown validation); human; 1:1000; fig 5	Granato M, Santarelli R, Filardi M, Gonnella R, Farina A, Torrisi M, et al. The activation of KSHV lytic cycle blocks autophagy in PEL cells. Autophagy. 2015;11:1978-1986 pubmed
western blot; human; 1:1000; fig s2	Wu X, Fleming A, Ricketts T, Pavel M, Virgin H, Menzies F, et al. Autophagy regulates Notch degradation and modulates stem cell development and neurogenesis. Nat Commun. 2016;7:10533 pubmed publisher
western blot; rat	Triplett J, Tramutola A, Swomley A, Kirk J, Grimes K, Lewis K, et al. Age-related changes in the proteostasis network in the brain of the naked mole-rat: Implications promoting healthy longevity. Biochim Biophys Acta. 2015;1852:2213-24 pubmed publisher
immunohistochemistry - free floating section; rat	Gorojod R, Alaimo A, Porte Alcon S, Pomilio C, Saravia F, Kotler M. The autophagic- lysosomal pathway determines the fate of glial cells under manganese- induced oxidative stress conditions. Free Radic Biol Med. 2015;87:237-51 pubmed publisher
western blot; mouse	Mir S, George N, Zahoor L, Harms R, Guinn Z, SARVETNICK N. Inhibition of autophagic turnover in β-cells by fatty acids and glucose leads to apoptotic cell death. J Biol Chem. 2015;290:6071-85 pubmed publisher
western blot; mouse; 1:1000	Chang A, Ulrich A, Suliman H, Piantadosi C. Redox regulation of mitophagy in the lung during murine Staphylococcus aureus sepsis. Free Radic Biol Med. 2015;78:179-89 pubmed publisher
western blot; rat; 1:500	Ortiz F, Acuna-Castroviejo D, Doerrier C, Dayoub J, Lopez L, Venegas C, et al. Melatonin blunts the mitochondrial/NLRP3 connection and protects against radiation-induced oral mucositis. J Pineal Res. 2015;58:34-49 pubmed publisher
western blot; mouse; fig 5, 7	Zemljic-Harpf A, Godoy J, Platoshyn O, Asfaw E, Busija A, Domenighetti A, et al. Vinculin directly binds zonula occludens-1 and is essential for stabilizing connexin-43-containing gap junctions in cardiac myocytes. J Cell Sci. 2014;127:1104-16 pubmed publisher
	Dong W, Xiao S, Cheng M, Ye X, Zheng G. Minocycline induces protective autophagy in vascular endothelial cells exposed to an in vitro model of ischemia/reperfusion-induced injury. Biomed Rep. 2016;4:173-177 pubmed
	Liang S, Figtree G, Aiqun M, Ping Z. GAPDH-knockdown reduce rotenone-induced H9C2 cells death via autophagy and anti-oxidative stress pathway. Toxicol Lett. 2015;234:162-71 pubmed publisher
	Shen C, Wang C, Fan F, Yang Z, Cao Q, Liu X, et al. Acetaldehyde dehydrogenase 2 (ALDH2) deficiency exacerbates pressure overload-induced cardiac dysfunction by inhibiting Beclin-1 dependent autophagy pathway. Biochim Biophys Acta. 2015;1852:310-8 pubmed publisher
	Correa R, Valdes Y, Peart T, Fazio E, Bertrand M, McGee J, et al. Combination of AKT inhibition with autophagy blockade effectively reduces ascites-derived ovarian cancer cell viability. Carcinogenesis. 2014;35:1951-61 pubmed publisher
	Gutierrez E, Richardson D, Jansson P. The anticancer agent di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone (Dp44mT) overcomes prosurvival autophagy by two mechanisms: persistent induction of autophagosome synthesis and impairment of lysosomal integrity. J Biol Chem. 2014;289:33568-89 pubmed publisher
	Hung T, Hsieh T, Chen S, Li M, Yeh Y. Autophagy in the human placenta throughout gestation. PLoS ONE. 2013;8:e83475 pubmed publisher
	Hung T, Chen S, Lo L, Li M, Yeh Y, Hsieh T. Increased autophagy in placentas of intrauterine growth-restricted pregnancies. PLoS ONE. 2012;7:e40957 pubmed publisher
	Shi C, Kehrl J. MyD88 and Trif target Beclin 1 to trigger autophagy in macrophages. J Biol Chem. 2008;283:33175-82 pubmed publisher
	Yang J, Takahashi Y, Cheng E, Liu J, Terranova P, Zhao B, et al. GSK-3beta promotes cell survival by modulating Bif-1-dependent autophagy and cell death. J Cell Sci. 2010;123:861-70 pubmed publisher

product information

SKU :

3738S

Product-Name :

Beclin-1 Antibody

Size :

100 ul

Price-(USD) :

235 USD

Species-x-Reactivity :

H, M, R

Applications :

Immunoprecipitation

Product-Category :

Autophagy

Shipping-Temp :

AMBIENT

Storage-Temp :

-20°C

Product-Type :

Polyclonal Antibody

MW :

Host :

Rabbit

Target :

Beclin 1

Primary-Protein :

beclin 1

Alt-Names :

ATG6,ATG6 autophagy related 6 homolog,BECN1,Beclin-1,Coiled-coil myosin-like BCL2-interacting protein,GT197,Protein GT197,VPS30,beclin 1 (coiled-coil, moesin-like BCL2 interacting protein),beclin 1 (coiled-coil, moesin-like BCL2-interacting protein),beclin 1, autophagy related,beclin1

more info or order :

Cell Signaling Technology product webpage