product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
TGF-β Receptor I Antibody
catalog :
3712
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, rat
application :
western blot
citations: 13
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 2k
Matkar P, Singh K, Rudenko D, Kim Y, Kuliszewski M, Prud homme G, et al. Novel regulatory role of neuropilin-1 in endothelial-to-mesenchymal transition and fibrosis in pancreatic ductal adenocarcinoma. Oncotarget. 2016;7:69489-69506 pubmed publisher
  • western blot; human; 1:1000; fig 3
Bassey Archibong B, Kwiecien J, Milosavljevic S, Hallett R, Rayner L, Erb M, et al. Kaiso depletion attenuates transforming growth factor-? signaling and metastatic activity of triple-negative breast cancer cells. Oncogenesis. 2016;5:e208 pubmed publisher
  • western blot; human; 1:1000; fig s3
Buczek M, Miles A, Green W, Johnson C, Boocock D, Pockley A, et al. Cytoplasmic PML promotes TGF-β-associated epithelial-mesenchymal transition and invasion in prostate cancer. Oncogene. 2016;35:3465-75 pubmed publisher
  • western blot; human; fig s1
Bauer J, Ozden O, Akagi N, Carroll T, Principe D, Staudacher J, et al. Activin and TGFβ use diverging mitogenic signaling in advanced colon cancer. Mol Cancer. 2015;14:182 pubmed publisher
  • western blot; human; fig 6
Zhao L, Liu S, Che X, Hou K, Ma Y, Li C, et al. Bufalin inhibits TGF-β-induced epithelial-to-mesenchymal transition and migration in human lung cancer A549 cells by downregulating TGF-β receptors. Int J Mol Med. 2015;36:645-52 pubmed publisher
  • western blot; rat; fig 4
Xu T, Pan Z, Dong M, Yu C, Niu Y. Ferulic acid suppresses activation of hepatic stellate cells through ERK1/2 and Smad signaling pathways in vitro. Biochem Pharmacol. 2015;93:49-58 pubmed publisher
  • western blot; human; fig s3
Gray A, Stephens C, Bigelow R, Coleman D, Cardelli J. The polyphenols (-)-epigallocatechin-3-gallate and luteolin synergistically inhibit TGF-β-induced myofibroblast phenotypes through RhoA and ERK inhibition. PLoS ONE. 2014;9:e109208 pubmed publisher
Hong S, Noh H, Teng Y, Shao J, Rehmani H, Ding H, et al. SHOX2 is a direct miR-375 target and a novel epithelial-to-mesenchymal transition inducer in breast cancer cells. Neoplasia. 2014;16:279-90.e1-5 pubmed publisher
Bar Klein G, Cacheaux L, Kamintsky L, Prager O, Weissberg I, Schoknecht K, et al. Losartan prevents acquired epilepsy via TGF-? signaling suppression. Ann Neurol. 2014;75:864-75 pubmed publisher
Lv J, Zhao Z, Chen Y, Wang Q, Tao Y, Yang L, et al. The chinese herbal decoction danggui buxue tang inhibits angiogenesis in a rat model of liver fibrosis. Evid Based Complement Alternat Med. 2012;2012:284963 pubmed publisher
Moyano J, Greciano P, Buschmann M, Koch M, Matlin K. Autocrine transforming growth factor-{beta}1 activation mediated by integrin {alpha}V{beta}3 regulates transcriptional expression of laminin-332 in Madin-Darby canine kidney epithelial cells. Mol Biol Cell. 2010;21:3654-68 pubmed publisher
Van Themsche C, Chaudhry P, Leblanc V, Parent S, Asselin E. XIAP gene expression and function is regulated by autocrine and paracrine TGF-beta signaling. Mol Cancer. 2010;9:216 pubmed publisher
Wang Q, Tao Y, Yuan J, Shen L, Liu C. Salvianolic acid B prevents epithelial-to-mesenchymal transition through the TGF-beta1 signal transduction pathway in vivo and in vitro. BMC Cell Biol. 2010;11:31 pubmed publisher
product information
SKU :
3712S
Product-Name :
TGF-β Receptor I Antibody
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, R, Mi, (Pg)
Applications :
Western blot
Product-Category :
Developmental Biology
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
52
Host :
Rabbit
Target :
TGFbR1
Primary-Protein :
TGFBR1
Alt-Names :
AAT5,ACVRLK4,ALK-5,ALK5,Activin receptor-like kinase 5,LDS1A,LDS2A,SKR4,Serine/threonine-protein kinase receptor R4,TGF-beta receptor type I,TGF-beta receptor type-1,TGF-beta type I receptor,TGFBR1,TGFR-1,TGFR1,TbetaR-I,Transforming growth factor-beta receptor type I,activin A receptor type II-like kinase, 53kD,activin A receptor type II-like kinase, 53kDa,transforming growth factor beta receptor I,transforming growth factor, beta receptor 1,transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53kD)
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.