product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
TGF-β (56E4) Rabbit mAb
catalog :
3709
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
56E4
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry
citations: 12
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; 1:100; loading ...; fig 2a
  • western blot; mouse; 1:1000; loading ...; fig 2h, 4c
van de Vlekkert D, Demmers J, Nguyen X, Campos Y, Machado E, Annunziata I, et al. Excessive exosome release is the pathogenic pathway linking a lysosomal deficiency to generalized fibrosis. Sci Adv. 2019;5:eaav3270 pubmed publisher
  • western blot; rat; 1:100; loading ...; fig 1d
Hoa N, Ge L, Korach K, Levin E. Estrogen receptor beta maintains expression of KLF15 to prevent cardiac myocyte hypertrophy in female rodents. Mol Cell Endocrinol. 2018;470:240-250 pubmed publisher
  • western blot; human; 1:2000; loading ...; fig 8a
Wu K, Zhao Z, Ma J, Chen J, Peng J, Yang S, et al. Deregulation of miR-193b affects the growth of colon cancer cells via transforming growth factor-? and regulation of the SMAD3 pathway. Oncol Lett. 2017;13:2557-2562 pubmed publisher
  • western blot; human; 1:500; loading ...; fig 2b
Hoare M, Ito Y, Kang T, Weekes M, Matheson N, Patten D, et al. NOTCH1 mediates a switch between two distinct secretomes during senescence. Nat Cell Biol. 2016;18:979-92 pubmed publisher
  • western blot; mouse; loading ...; fig 3d, 4a
Yi H, Eun H, Lee Y, Jung J, Park S, Park K, et al. Treatment with 4-methylpyrazole modulated stellate cells and natural killer cells and ameliorated liver fibrosis in mice. PLoS ONE. 2015;10:e0127946 pubmed publisher
  • western blot; human; 1:1000
Chen F, Zhuang M, Peng J, Wang X, Huang T, Li S, et al. Baicalein inhibits migration and invasion of gastric cancer cells through suppression of the TGF-β signaling pathway. Mol Med Rep. 2014;10:1999-2003 pubmed publisher
Tsai C, Kao Y, Chiang I, Wang J, Young T. Chitosan Treatment Delays the Induction of Senescence in Human Foreskin Fibroblast Strains. PLoS ONE. 2015;10:e0140747 pubmed publisher
Maier A, Peille A, Vuaroqueaux V, Lahn M. Anti-tumor activity of the TGF-β receptor kinase inhibitor galunisertib (LY2157299 monohydrate) in patient-derived tumor xenografts. Cell Oncol (Dordr). 2015;38:131-44 pubmed publisher
Hu J, Jo M, Eastman B, Gilder A, Bui J, Gonias S. uPAR induces expression of transforming growth factor β and interleukin-4 in cancer cells to promote tumor-permissive conditioning of macrophages. Am J Pathol. 2014;184:3384-93 pubmed publisher
Yuan X, Wei Q, Komaki R, Liu Z, Yang J, Tucker S, et al. TGF?1 Polymorphisms Predict Distant Metastasis-Free Survival in Patients with Inoperable Non-Small-Cell Lung Cancer after Definitive Radiotherapy. PLoS ONE. 2013;8:e65659 pubmed publisher
Meinen S, Lin S, Ruegg M. Angiotensin II type 1 receptor antagonists alleviate muscle pathology in the mouse model for laminin-?2-deficient congenital muscular dystrophy (MDC1A). Skelet Muscle. 2012;2:18 pubmed publisher
Shrivastav A, Suri S, Mohr R, Janardhan K, Sharma R, Singh B. Expression and activity of N-myristoyltransferase in lung inflammation of cattle and its role in neutrophil apoptosis. Vet Res. 2010;41:9 pubmed publisher
product information
SKU :
3709S
Product-Name :
TGF-β (56E4) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, (M, R, Pg)
Applications :
Western blot
Product-Category :
Developmental Biology
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
12, 45-60
Host :
Rabbit
Target :
TGF-beta1/TGF-beta2/TGF-beta3
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.