| Published Application/Species/Dilution | Reference |
|---|
- western blot; human; 1:1000; fig s3
- western blot; mouse; 1:1000; fig s3
| Casasola A, Scalzo D, Nandakumar V, Halow J, Recillas-Targa F, Groudine M, et al. Prelamin A processing, accumulation and distribution in normal cells and laminopathy disorders. Nucleus. 2016;7:84-102 pubmed publisher |
- western blot; mouse; 1:3000; fig 4
| Dinger K, Kasper P, Hucklenbruch-Rother E, Vohlen C, Jobst E, Janoschek R, et al. Early-onset obesity dysregulates pulmonary adipocytokine/insulin signaling and induces asthma-like disease in mice. Sci Rep. 2016;6:24168 pubmed publisher |
- western blot; human; fig 2
| Franzese O, Palermo B, Di Donna C, Sperduti I, Ferraresi V, Stabile H, et al. Polyfunctional Melan-A-specific tumor-reactive CD8(+) T cells elicited by dacarbazine treatment before peptide-vaccination depends on AKT activation sustained by ICOS. Oncoimmunology. 2016;5:e1114203 pubmed publisher |
- western blot; rat; 1:1000; fig 6
| Jiao K, Zeng G, Niu L, Yang H, Ren G, Xu X, et al. Activation of α2A-adrenergic signal transduction in chondrocytes promotes degenerative remodelling of temporomandibular joint. Sci Rep. 2016;6:30085 pubmed publisher |
- western blot; mouse; 1:1000; fig 1
| Zhang H, Kang E, Wang Y, Yang C, Yu H, Wang Q, et al. Brain-specific Crmp2 deletion leads to neuronal development deficits and behavioural impairments in mice. Nat Commun. 2016;7: pubmed publisher |
- western blot; human; fig 1
| Murakami-Tonami Y, Ikeda H, Yamagishi R, Inayoshi M, Inagaki S, Kishida S, et al. SGO1 is involved in the DNA damage response in MYCN-amplified neuroblastoma cells. Sci Rep. 2016;6:31615 pubmed publisher |
- western blot; mouse; 1:2000; fig 2
| Miao H, Ou J, Peng Y, Zhang X, Chen Y, Hao L, et al. Macrophage ABHD5 promotes colorectal cancer growth by suppressing spermidine production by SRM. Nat Commun. 2016;7:11716 pubmed publisher |
- western blot; human; 1:1000; fig 3
| Sahu N, Stephan J, Cruz D, Merchant M, Haley B, Bourgon R, et al. Functional screening implicates miR-371-3p and peroxiredoxin 6 in reversible tolerance to cancer drugs. Nat Commun. 2016;7:12351 pubmed publisher |
- western blot; mouse; 1:1000; fig 1
| Yang Y, Zhang Y, Iwamoto H, Hosaka K, Seki T, Andersson P, et al. Discontinuation of anti-VEGF cancer therapy promotes metastasis through a liver revascularization mechanism. Nat Commun. 2016;7:12680 pubmed publisher |
- western blot; human; 1:5000; fig 3
| Li Q, Guo Y, Chen F, Liu J, Jin P. Stromal cell-derived factor-1 promotes human adipose tissue-derived stem cell survival and chronic wound healing. Exp Ther Med. 2016;12:45-50 pubmed |
- western blot; human; fig 3
| Zhang J, Lachance V, Schaffner A, Li X, Fedick A, Kaye L, et al. A Founder Mutation in VPS11 Causes an Autosomal Recessive Leukoencephalopathy Linked to Autophagic Defects. PLoS Genet. 2016;12:e1005848 pubmed publisher |
- western blot; rat; 1:1000; fig 7B
| Fang J, Jia C, Zheng Z, Ye X, Wei B, Huang L, et al. Periprostatic implantation of neural differentiated mesenchymal stem cells restores cavernous nerve injury-mediated erectile dysfunction. Am J Transl Res. 2016;8:2549-61 pubmed |
- western blot; mouse; 1:1000; fig 4
| Mehrabian M, Brethour D, Williams D, Wang H, Arnould H, Schneider B, et al. Prion Protein Deficiency Causes Diverse Proteome Shifts in Cell Models That Escape Detection in Brain Tissue. PLoS ONE. 2016;11:e0156779 pubmed publisher |
- western blot; rat; 1:4000; fig 7
| Dong Y, Bao C, Yu J, Liu X. Receptor-interacting protein kinase 3-mediated programmed cell necrosis in rats subjected to focal cerebral ischemia-reperfusion injury. Mol Med Rep. 2016;14:728-36 pubmed publisher |
- western blot; rat; 1:20,000; fig 6
| Li J, Su Y, Wang H, Zhao Y, Liao X, Wang X, et al. Repeated Blockade of NMDA Receptors During Adolescence Impairs Reversal Learning and Disrupts GABAergic Interneurons in Rat Medial Prefrontal Cortex. Front Mol Neurosci. 2016;9:17 pubmed publisher |
- western blot; human; fig 1
| Lim S, Liu H, Madeira da Silva L, Arora R, Liu Z, Phillips J, et al. Immunoregulatory Protein B7-H3 Reprograms Glucose Metabolism in Cancer Cells by ROS-Mediated Stabilization of HIF1α. Cancer Res. 2016;76:2231-42 pubmed publisher |
- western blot; mouse; 1:1000; fig 2
| Ma Y, Guo H, Zhang L, Tao L, Yin A, Liu Z, et al. Estrogen replacement therapy-induced neuroprotection against brain ischemia-reperfusion injury involves the activation of astrocytes via estrogen receptor β. Sci Rep. 2016;6:21467 pubmed publisher |
- western blot; human; fig 4
| Zhuang L, Yang Y, Ma X, Han B, Wang Z, Zhao Q, et al. MicroRNA-92b promotes hepatocellular carcinoma progression by targeting Smad7 and is mediated by long non-coding RNA XIST. Cell Death Dis. 2016;7:e2203 pubmed publisher |
- western blot; human; fig 8
| Yu J, Berga S, Johnston-MacAnanny E, Sidell N, Bagchi I, Bagchi M, et al. Endometrial Stromal Decidualization Responds Reversibly to Hormone Stimulation and Withdrawal. Endocrinology. 2016;157:2432-46 pubmed publisher |
- western blot; human; 1:1000; fig 2
| Ortuno D, Carlisle H, Miller S. Does inactivation of USP14 enhance degradation of proteasomal substrates that are associated with neurodegenerative diseases?. F1000Res. 2016;5:137 pubmed publisher |
- western blot; human; fig s3
- western blot; mouse; fig 4
| Yang Y, Andersson P, Hosaka K, Zhang Y, Cao R, Iwamoto H, et al. The PDGF-BB-SOX7 axis-modulated IL-33 in pericytes and stromal cells promotes metastasis through tumour-associated macrophages. Nat Commun. 2016;7:11385 pubmed publisher |
- western blot; human; fig 5
| Mester T, Raychaudhuri N, Gillespie E, Chen H, Smith T, Douglas R. CD40 Expression in Fibrocytes Is Induced by TSH: Potential Synergistic Immune Activation. PLoS ONE. 2016;11:e0162994 pubmed publisher |
- western blot; mouse; 1:10,000; fig 7
| Velázquez R, Shaw D, Caccamo A, Oddo S. Pim1 inhibition as a novel therapeutic strategy for Alzheimer's disease. Mol Neurodegener. 2016;11:52 pubmed publisher |
- western blot; human; 1:5000; fig 2
| Ortmann B, Bensaddek D, Carvalhal S, Moser S, Mudie S, Griffis E, et al. CDK-dependent phosphorylation of PHD1 on serine 130 alters its substrate preference in cells. J Cell Sci. 2016;129:191-205 pubmed publisher |
- western blot; human; fig 1a
| Moniz S, Bandarra D, Biddlestone J, Campbell K, Komander D, Bremm A, et al. Cezanne regulates E2F1-dependent HIF2α expression. J Cell Sci. 2015;128:3082-93 pubmed publisher |
| Wu C, Niu L, Yan Z, Wang C, Liu N, Dai Y, et al. Pcdh11x Negatively Regulates Dendritic Branching. J Mol Neurosci. 2015;56:822-8 pubmed publisher |
- western blot; human; fig 2
| Crauwels P, Bohn R, Thomas M, Gottwalt S, Jäckel F, Krämer S, et al. Apoptotic-like Leishmania exploit the host's autophagy machinery to reduce T-cell-mediated parasite elimination. Autophagy. 2015;11:285-97 pubmed publisher |
- western blot; human; fig 2
| Momeny M, Saunus J, Marturana F, McCart Reed A, Black D, Sala G, et al. Heregulin-HER3-HER2 signaling promotes matrix metalloproteinase-dependent blood-brain-barrier transendothelial migration of human breast cancer cell lines. Oncotarget. 2015;6:3932-46 pubmed |
| Mir S, George N, Zahoor L, Harms R, Guinn Z, SARVETNICK N. Inhibition of autophagic turnover in β-cells by fatty acids and glucose leads to apoptotic cell death. J Biol Chem. 2015;290:6071-85 pubmed publisher |
- other; human; fig 3
- western blot; human; 1:3; fig s17
| Chan-Penebre E, Kuplast K, Majer C, Boriack-Sjodin P, Wigle T, Johnston L, et al. A selective inhibitor of PRMT5 with in vivo and in vitro potency in MCL models. Nat Chem Biol. 2015;11:432-7 pubmed publisher |
- western blot; human; 1:5000
| Grice S, Sleigh J, Motley W, Liu J, Burgess R, Talbot K, et al. Dominant, toxic gain-of-function mutations in gars lead to non-cell autonomous neuropathology. Hum Mol Genet. 2015;24:4397-406 pubmed publisher |
- western blot; human; fig 2
| Zucal C, D'Agostino V, Casini A, Mantelli B, Thongon N, Soncini D, et al. EIF2A-dependent translational arrest protects leukemia cells from the energetic stress induced by NAMPT inhibition. BMC Cancer. 2015;15:855 pubmed publisher |
| Meadows S, Cleaver O. Annexin A3 Regulates Early Blood Vessel Formation. PLoS ONE. 2015;10:e0132580 pubmed publisher |
- western blot; rat; 1:1000
| Jin S, Liu Y, Deng S, Liao L, Lin T, Ning Q, et al. Neuroprotective effects of activated protein C on intrauterine inflammation-induced neonatal white matter injury are associated with the downregulation of fibrinogen-like protein 2/fibroleukin prothrombinase and the inhibition of pro-inflammatory cytokine. Int J Mol Med. 2015;35:1199-212 pubmed publisher |
- western blot; human; 1:750; fig 4
| Boros G, Miko E, Muramatsu H, Weissman D, Emri E, van der Horst G, et al. Identification of Cyclobutane Pyrimidine Dimer-Responsive Genes Using UVB-Irradiated Human Keratinocytes Transfected with In Vitro-Synthesized Photolyase mRNA. PLoS ONE. 2015;10:e0131141 pubmed publisher |
- western blot; mouse; 1:3000; fig s10
| Yan S, Xu Z, Lou F, Zhang L, Ke F, Bai J, et al. NF-κB-induced microRNA-31 promotes epidermal hyperplasia by repressing protein phosphatase 6 in psoriasis. Nat Commun. 2015;6:7652 pubmed publisher |
| Guerrouahen B, Pasquier J, Kaoud N, Maleki M, Beauchamp M, Yasmeen A, et al. Akt-activated endothelium constitutes the niche for residual disease and resistance to bevacizumab in ovarian cancer. Mol Cancer Ther. 2014;13:3123-36 pubmed publisher |
- western blot; human; fig 1
| Mudie S, Bandarra D, Batie M, Biddlestone J, Moniz S, Ortmann B, et al. PITX1, a specificity determinant in the HIF-1α-mediated transcriptional response to hypoxia. Cell Cycle. 2014;13:3878-91 pubmed publisher |
- western blot; rat; 1:1000
| Killinger B, Shah M, Moszczynska A. Co-administration of betulinic acid and methamphetamine causes toxicity to dopaminergic and serotonergic nerve terminals in the striatum of late adolescent rats. J Neurochem. 2014;128:764-75 pubmed publisher |
| Zhan Z, Xie X, Cao H, Zhou X, Zhang X, Fan H, et al. Autophagy facilitates TLR4- and TLR3-triggered migration and invasion of lung cancer cells through the promotion of TRAF6 ubiquitination. Autophagy. 2014;10:257-68 pubmed publisher |
- western blot; human; 1:5000
| Warren C, Griffin L, Little A, Huang I, Farzan M, Pyeon D. The antiviral restriction factors IFITM1, 2 and 3 do not inhibit infection of human papillomavirus, cytomegalovirus and adenovirus. PLoS ONE. 2014;9:e96579 pubmed publisher |
| Chen H, Mester T, Raychaudhuri N, Kauh C, Gupta S, Smith T, et al. Teprotumumab, an IGF-1R blocking monoclonal antibody inhibits TSH and IGF-1 action in fibrocytes. J Clin Endocrinol Metab. 2014;99:E1635-40 pubmed publisher |
- western blot; mouse; 1:1000
| Naidoo N, Davis J, Zhu J, Yabumoto M, Singletary K, Brown M, et al. Aging and sleep deprivation induce the unfolded protein response in the pancreas: implications for metabolism. Aging Cell. 2014;13:131-41 pubmed publisher |
| Hasanali Z, Epner E, Feith D, Loughran T, Sample C. Vorinostat downregulates CD30 and decreases brentuximab vedotin efficacy in human lymphocytes. Mol Cancer Ther. 2014;13:2784-92 pubmed publisher |
| Kainulainen M, Habjan M, Hubel P, Busch L, Lau S, Colinge J, et al. Virulence factor NSs of rift valley fever virus recruits the F-box protein FBXO3 to degrade subunit p62 of general transcription factor TFIIH. J Virol. 2014;88:3464-73 pubmed publisher |
| Gillespie E, Raychaudhuri N, Papageorgiou K, Atkins S, Lu Y, Charara L, et al. Interleukin-6 production in CD40-engaged fibrocytes in thyroid-associated ophthalmopathy: involvement of Akt and NF-κB. Invest Ophthalmol Vis Sci. 2012;53:7746-53 pubmed publisher |
| Wen S, Jadhav K, Williamson D, Rideout T. Treadmill Exercise Training Modulates Hepatic Cholesterol Metabolism and Circulating PCSK9 Concentration in High-Fat-Fed Mice. J Lipids. 2013;2013:908048 pubmed publisher |
| Lin R, Yu K, Li X, Tao J, Lin Y, Zhao C, et al. Electroacupuncture ameliorates post-stroke learning and memory through minimizing ultrastructural brain damage and inhibiting the expression of MMP-2 and MMP-9 in cerebral ischemia-reperfusion injured rats. Mol Med Rep. 2016;14:225-33 pubmed publisher |
| Yang R, Zhong L, Yang X, Jiang K, Li L, Song H, et al. Neutrophil elastase enhances the proliferation and decreases apoptosis of leukemia cells via activation of PI3K/Akt signaling. Mol Med Rep. 2016;13:4175-82 pubmed publisher |
| Wang H, Teriete P, Hu A, Raveendra-Panickar D, Pendelton K, Lazo J, et al. Direct inhibition of c-Myc-Max heterodimers by celastrol and celastrol-inspired triterpenoids. Oncotarget. 2015;6:32380-95 pubmed publisher |
| Wang H, Sharma L, Lu J, Finch P, Fletcher S, Prochownik E. Structurally diverse c-Myc inhibitors share a common mechanism of action involving ATP depletion. Oncotarget. 2015;6:15857-70 pubmed |
| Hwang S, Disatnik M, Mochly-Rosen D. Impaired GAPDH-induced mitophagy contributes to the pathology of Huntington's disease. EMBO Mol Med. 2015;7:1307-26 pubmed publisher |
| Wright D, Renoir T, Smith Z, Frazier A, Francis P, Thorburn D, et al. N-Acetylcysteine improves mitochondrial function and ameliorates behavioral deficits in the R6/1 mouse model of Huntington's disease. Transl Psychiatry. 2015;5:e492 pubmed publisher |
| Li J, Lam M. Registered report: the microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44. elife. 2015;4:e06434 pubmed publisher |
| Fan C, Wang Y, Liu Z, Sun Y, Wang X, Wei G, et al. Metformin exerts anticancer effects through the inhibition of the Sonic hedgehog signaling pathway in breast cancer. Int J Mol Med. 2015;36:204-14 pubmed publisher |
| Korhonova M, Doricakova A, Dvorak Z. Optical Isomers of Atorvastatin, Rosuvastatin and Fluvastatin Enantiospecifically Activate Pregnane X Receptor PXR and Induce CYP2A6, CYP2B6 and CYP3A4 in Human Hepatocytes. PLoS ONE. 2015;10:e0137720 pubmed publisher |
| Hung M, Leonard J. Stabilization of exosome-targeting peptides via engineered glycosylation. J Biol Chem. 2015;290:8166-72 pubmed publisher |
| Levring T, Kongsbak M, Rode A, Woetmann A, Ødum N, Bonefeld C, et al. Human CD4+ T cells require exogenous cystine for glutathione and DNA synthesis. Oncotarget. 2015;6:21853-64 pubmed |
| Li M, Yang Y, He Z, Zhou Z, Yang T, Guo P, et al. MicroRNA-561 promotes acetaminophen-induced hepatotoxicity in HepG2 cells and primary human hepatocytes through downregulation of the nuclear receptor corepressor dosage-sensitive sex-reversal adrenal hypoplasia congenital critical region on the X chromos. Drug Metab Dispos. 2014;42:44-61 pubmed publisher |
| Wang F, Awan U, Wang Y, Wang L, Qing H, Ma H, et al. Damage of neuroblastoma cell SH-SY5Y mediated by MPP+ inhibits proliferation of T-cell leukemia Jurkat by co-culture system. Int J Mol Sci. 2014;15:10738-50 pubmed publisher |
| Zhou Q, Jiang L, Xu C, Luo D, Zeng C, Liu P, et al. Ginsenoside Rg1 inhibits platelet activation and arterial thrombosis. Thromb Res. 2014;133:57-65 pubmed publisher |
| Fortin D, Tillo S, Yang G, Rah J, Melander J, Bai S, et al. Live imaging of endogenous PSD-95 using ENABLED: a conditional strategy to fluorescently label endogenous proteins. J Neurosci. 2014;34:16698-712 pubmed publisher |
| Cai M, Liu P, Wei L, Wang J, Qi J, Feng S, et al. Atp6v1c1 may regulate filament actin arrangement in breast cancer cells. PLoS ONE. 2014;9:e84833 pubmed publisher |
| Baxter P, Lin Q, Mao H, Kogiso M, Zhao X, Liu Z, et al. Silencing BMI1 eliminates tumor formation of pediatric glioma CD133+ cells not by affecting known targets but by down-regulating a novel set of core genes. Acta Neuropathol Commun. 2014;2:160 pubmed publisher |
| Logan R, Kong A, Krise J. Time-dependent effects of hydrophobic amine-containing drugs on lysosome structure and biogenesis in cultured human fibroblasts. J Pharm Sci. 2014;103:3287-96 pubmed publisher |
| Gajdosechova L, Krskova K, Segarra A, Špolcová A, Suski M, Olszanecki R, et al. Hypooxytocinaemia in obese Zucker rats relates to oxytocin degradation in liver and adipose tissue. J Endocrinol. 2014;220:333-43 pubmed publisher |
| Burcham G, Cresswell G, Snyder P, Chen L, Liu X, Crist S, et al. Impact of prostate inflammation on lesion development in the POET3(+)Pten(+/-) mouse model of prostate carcinogenesis. Am J Pathol. 2014;184:3176-91 pubmed publisher |
| Torocsik D, Kovacs D, Camera E, Lovászi M, Cseri K, Nagy G, et al. Leptin promotes a proinflammatory lipid profile and induces inflammatory pathways in human SZ95 sebocytes. Br J Dermatol. 2014;171:1326-35 pubmed publisher |
| Bracarense A, Lucioli J, Grenier B, Drociunas Pacheco G, Moll W, Schatzmayr G, et al. Chronic ingestion of deoxynivalenol and fumonisin, alone or in interaction, induces morphological and immunological changes in the intestine of piglets. Br J Nutr. 2012;107:1776-86 pubmed publisher |
| Srivastava A, Srivastava P, Al-Khedhairy A, Musarrat J, Shukla Y. Allethrin-induced genotoxicity and oxidative stress in Swiss albino mice. Mutat Res. 2012;747:22-8 pubmed publisher |
| Lai Y, Cheng J, Cheng D, Feasel M, Beste K, Peng J, et al. SOX4 interacts with plakoglobin in a Wnt3a-dependent manner in prostate cancer cells. BMC Cell Biol. 2011;12:50 pubmed publisher |
| Tarassishin L, Loudig O, Bauman A, Shafit-Zagardo B, Suh H, Lee S. Interferon regulatory factor 3 inhibits astrocyte inflammatory gene expression through suppression of the proinflammatory miR-155 and miR-155*. Glia. 2011;59:1911-22 pubmed publisher |
| Balakrishnan B, Sen D, Hareendran S, Roshini V, David S, Srivastava A, et al. Activation of the cellular unfolded protein response by recombinant adeno-associated virus vectors. PLoS ONE. 2013;8:e53845 pubmed publisher |
| Liao R, Jung J, Tchaicha J, Wilkerson M, Sivachenko A, Beauchamp E, et al. Inhibitor-sensitive FGFR2 and FGFR3 mutations in lung squamous cell carcinoma. Cancer Res. 2013;73:5195-205 pubmed publisher |
| Zheng Y, Zhang H, Zhang X, Feng D, Luo X, Zeng C, et al. MiR-100 regulates cell differentiation and survival by targeting RBSP3, a phosphatase-like tumor suppressor in acute myeloid leukemia. Oncogene. 2012;31:80-92 pubmed publisher |
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| Siegfried A, Berchtold S, Manncke B, Deuschle E, Reber J, Ott T, et al. IFIT2 is an effector protein of type I IFN-mediated amplification of lipopolysaccharide (LPS)-induced TNF-α secretion and LPS-induced endotoxin shock. J Immunol. 2013;191:3913-21 pubmed publisher |
| Logan R, Kong A, Krise J. Evaluating the roles of autophagy and lysosomal trafficking defects in intracellular distribution-based drug-drug interactions involving lysosomes. J Pharm Sci. 2013;102:4173-80 pubmed publisher |
| Ueno T, Endo S, Saito R, Hirose M, Hirai S, Suzuki H, et al. The sirtuin inhibitor tenovin-6 upregulates death receptor 5 and enhances cytotoxic effects of 5-fluorouracil and oxaliplatin in colon cancer cells. Oncol Res. 2013;21:155-64 pubmed publisher |
| Hu H, Li Z, Zhu X, Lin R, Lin J, Peng J, et al. Gua Lou Gui Zhi decoction suppresses LPS-induced activation of the TLR4/NF-κB pathway in BV-2 murine microglial cells. Int J Mol Med. 2013;31:1327-32 pubmed publisher |
| Tarassishin L, Suh H, Lee S. Interferon regulatory factor 3 plays an anti-inflammatory role in microglia by activating the PI3K/Akt pathway. J Neuroinflammation. 2011;8:187 pubmed publisher |
